BACKGROUND/AIM: The etiology of autism spectrum disorder (ASD) is unknown, even though it is hypothesized that a viral infection could trigger this disorder. The aim of this study was to evaluate the seropositivity rate and antibody level of Herpes Simplex Virus 1 (HSV1) and Herpes Simplex Virus 2 (HSV2) in children with ASD compared to same-aged healthy controls. PATIENTS AND METHODS: We compared seropositivity rate and levels of antibodies to HSV1/2 in 54 children with ASD (19 with autistic disorder and 35 with non-autistic ASD) and in 46 controls. RESULTS: Seropositivity rate and levels of anti-HSV1/2 were not dissimilar between cases and controls. Exposure to HSV2 was minimal. CONCLUSION: Rate of contact with HSV1 and HSV2 assessed by the mean of detection of specific antibodies was similar between children with ASD and healthy controls.
BACKGROUND/AIM: The etiology of autism spectrum disorder (ASD) is unknown, even though it is hypothesized that a viral infection could trigger this disorder. The aim of this study was to evaluate the seropositivity rate and antibody level of Herpes Simplex Virus 1 (HSV1) and Herpes Simplex Virus 2 (HSV2) in children with ASD compared to same-aged healthy controls. PATIENTS AND METHODS: We compared seropositivity rate and levels of antibodies to HSV1/2 in 54 children with ASD (19 with autistic disorder and 35 with non-autistic ASD) and in 46 controls. RESULTS: Seropositivity rate and levels of anti-HSV1/2 were not dissimilar between cases and controls. Exposure to HSV2 was minimal. CONCLUSION: Rate of contact with HSV1 and HSV2 assessed by the mean of detection of specific antibodies was similar between children with ASD and healthy controls.
Authors: Emanuela Zappulo; Maria Pia Riccio; Sandro Binda; Laura Pellegrinelli; Fabrizio Pregliasco; Antonio Riccardo Buonomo; Biagio Pinchera; Giordano D'Urso; Carmela Bravaccio; Guglielmo Borgia; Ivan Gentile Journal: In Vivo Date: 2018 Sep-Oct Impact factor: 2.155
Authors: Maria Pia Riccio; Gennaro Catone; Rosamaria Siracusano; Luisa Occhiati; Pia Bernardo; Emilia Sarnataro; Giuseppina Corrado; Carmela Bravaccio Journal: AIMS Public Health Date: 2020-10-15