Jost B Jonas1, Rupert R A Bourne2, Richard A White3, Seth R Flaxman4, Jill Keeffe5, Janet Leasher6, Kovin Naidoo7, Konrad Pesudovs8, Holly Price2, Tien Y Wong9, Serge Resnikoff10, Hugh R Taylor11. 1. Department of Ophthalmology, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany. Electronic address: Jost.Jonas@medma.uni-heidelberg.de. 2. Vision and Eye Research Unit, Anglia Ruskin University, Cambridge, United Kingdom. 3. Department of Genes and Environment, Division of Epidemiology, Norwegian Institute of Public Health, Oslo, Norway. 4. School of Computer Science and Heinz College, Carnegie Mellon University, Pittsburgh, Pennsylvania. 5. L.V. Prasad Eye Institute, Hyderabad, India. 6. Nova South Eastern University, Fort Lauderdale, Florida. 7. African Vision Research Institute, University of Kwazulu-Natal, South Africa, and the Brien Holden Vision Institute, Sydney, Australia. 8. NHMRC Centre for Clinical Eye Research, Flinders University, Adelaide, Australia. 9. Singapore Eye Research Institute, Singapore. 10. Brien Holden Vision Institute, Sydney, Australia. 11. Melbourne School of Population and Global Health, University of Melbourne, Australia.
Abstract
PURPOSE: To estimate the number of people visually impaired or blind due to macular diseases except those caused by diabetic maculopathy. DESIGN: Meta-analysis. METHODS: Based on the Global Burden of Disease Study 2010 and ongoing literature research, we examined how many people were affected by vision impairment (presenting visual acuity <6/18, ≥3/60) and blindness (presenting visual acuity <3/60) due to macular diseases, with diabetic maculopathy excluded. RESULTS: In 2010, of 32.4 million blind people and 191 million vision-impaired people, 2.1 million (95% uncertainty interval [UI]: 1.9, 2.7) people were blind, and 6.0 million (95% UI: 5.2, 8.1) million were visually impaired due to macular diseases. In 2010, macular diseases caused 6.6% (95% UI: 6.0, 7.9) of all blindness and 3.1% (95% UI: 2.7, 4.0) of all vision impairment, worldwide. These figures were lower in regions with young populations than in high-income regions. Between 1990 and 2010, the number of people who were blind or visually impaired due to macular diseases increased by 36%, or 0.6 million people (95% UI: 0.5, 0.8) and by 81%, or 2.7 million (95% UI: 2.6, 3.9) people, respectively, whereas the global population increased by 30%. Age-standardized global prevalence of macula-related blindness and vision impairment in adults 50 years of age and older decreased from 0.2% (95% UI: 0.2, 0.2) in 1990 to 0.1% (95% UI: 0.1, 0.2) in 2010 and remained unchanged from 0.4% (95% UI: 0.3, 0.5) to 0.4% (95% UI: 0.4, 0.6), respectively. CONCLUSIONS: In 2010, 2.1 million people were blind and 6.0 million people were visually impaired due to macular diseases, except those caused by diabetic maculopathy. Of every 15 blind people, 1 was blind due to macular disease, and of every 32 visually impaired people, 1 was visually impaired due to macular disease.
PURPOSE: To estimate the number of people visually impaired or blind due to macular diseases except those caused by diabetic maculopathy. DESIGN: Meta-analysis. METHODS: Based on the Global Burden of Disease Study 2010 and ongoing literature research, we examined how many people were affected by vision impairment (presenting visual acuity <6/18, ≥3/60) and blindness (presenting visual acuity <3/60) due to macular diseases, with diabetic maculopathy excluded. RESULTS: In 2010, of 32.4 million blind people and 191 million vision-impaired people, 2.1 million (95% uncertainty interval [UI]: 1.9, 2.7) people were blind, and 6.0 million (95% UI: 5.2, 8.1) million were visually impaired due to macular diseases. In 2010, macular diseases caused 6.6% (95% UI: 6.0, 7.9) of all blindness and 3.1% (95% UI: 2.7, 4.0) of all vision impairment, worldwide. These figures were lower in regions with young populations than in high-income regions. Between 1990 and 2010, the number of people who were blind or visually impaired due to macular diseases increased by 36%, or 0.6 million people (95% UI: 0.5, 0.8) and by 81%, or 2.7 million (95% UI: 2.6, 3.9) people, respectively, whereas the global population increased by 30%. Age-standardized global prevalence of macula-related blindness and vision impairment in adults 50 years of age and older decreased from 0.2% (95% UI: 0.2, 0.2) in 1990 to 0.1% (95% UI: 0.1, 0.2) in 2010 and remained unchanged from 0.4% (95% UI: 0.3, 0.5) to 0.4% (95% UI: 0.4, 0.6), respectively. CONCLUSIONS: In 2010, 2.1 million people were blind and 6.0 million people were visually impaired due to macular diseases, except those caused by diabetic maculopathy. Of every 15 blind people, 1 was blind due to macular disease, and of every 32 visually impairedpeople, 1 was visually impaired due to macular disease.
Authors: Anna C S Tan; Polina Astroz; Kunal K Dansingani; Jason S Slakter; Lawrence A Yannuzzi; Christine A Curcio; K Bailey Freund Journal: Invest Ophthalmol Vis Sci Date: 2017-04-01 Impact factor: 4.799
Authors: Márta Kasza; J Meleg; J Vardai; B Nagy; E Szalai; J Damjanovich; A Csutak; B Ujhelyi; V Nagy Journal: Graefes Arch Clin Exp Ophthalmol Date: 2016-07-04 Impact factor: 3.117