Literature DB >> 24973350

Soft tissue injury of the lower extremity complicated by type II necrotising fasciitis highlighting the need for astute clinical practices and proper treatment.

Alexander Sabre1, Carlos G Robles1, Patricia Krisar-White2, Laurie Farricielli3.   

Abstract

Necrotising fasciitis (NF) is a soft tissue bacterial-derived infection characterised clinically by fulminant tissue destruction of the poorly blood-supplied muscle fascia and overlying subcutaneous fat. Although these infections first appear as minor superficial manifestations, they are capricious in nature and often lead to sepsis, organ failure and high mortality. We report a case of type II necrotising fasciitis in a 39-year-old Caucasian female patient who presented to the emergency department with cellulitis of her right foot and lower leg that rapidly developed into tissue necrosis. The patient course is of unique interest due to progressive history over a 104 days time frame with complications following surgical treatments and outpatient follow-up. We highlight the importance of early detection and pertinent clinical awareness from a wide range of medical specialties that were involved in this case, and how this process is critical, in order to properly diagnose and treat NF-derived tissue infections. 2014 BMJ Publishing Group Ltd.

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Mesh:

Year:  2014        PMID: 24973350      PMCID: PMC4078426          DOI: 10.1136/bcr-2014-204720

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  8 in total

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Authors:  Frédérique Sablier; Tayeb Slaouti; Pierre-Alexandre Drèze; Pierre Emmanuel El Fouly; Daniel Allemeersch; Laurence Van Melderen; Pierre R Smeesters
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Review 2.  Mechanisms and clinical applications of the vacuum-assisted closure (VAC) Device: a review.

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Journal:  Ann Surg       Date:  2006-11       Impact factor: 12.969

Review 4.  Streptococcal infections of skin and soft tissues.

Authors:  A L Bisno; D L Stevens
Journal:  N Engl J Med       Date:  1996-01-25       Impact factor: 91.245

5.  Group A streptococcal myonecrosis: increased vimentin expression after skeletal-muscle injury mediates the binding of Streptococcus pyogenes.

Authors:  Amy E Bryant; Clifford R Bayer; Jeremy D Huntington; Dennis L Stevens
Journal:  J Infect Dis       Date:  2006-05-10       Impact factor: 5.226

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Authors:  Marc G Jeschke; Christoph Rose; Peter Angele; Bernd Füchtmeier; Michael N Nerlich; Ulrich Bolder
Journal:  Plast Reconstr Surg       Date:  2004-02       Impact factor: 4.730

7.  Clinical and microbiological features of necrotizing fasciitis.

Authors:  I Brook; E H Frazier
Journal:  J Clin Microbiol       Date:  1995-09       Impact factor: 5.948

8.  Severe group A streptococcal infections associated with a toxic shock-like syndrome and scarlet fever toxin A.

Authors:  D L Stevens; M H Tanner; J Winship; R Swarts; K M Ries; P M Schlievert; E Kaplan
Journal:  N Engl J Med       Date:  1989-07-06       Impact factor: 91.245

  8 in total

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