Yimin Zhao1, Sailimuhan Asimi1, Kejian Wu1, Jusheng Zheng1, Duo Li2. 1. Department of Food Science and Nutrition, Zhejiang University, Hangzhou, People's Republic of China. 2. Department of Food Science and Nutrition, Zhejiang University, Hangzhou, People's Republic of China. Electronic address: duoli@zju.edu.cn.
Abstract
BACKGROUND & AIMS: The results of randomized controlled trials in relation to the effect of regular black tea consumption on serum cholesterol concentration were inconsistent. We aimed to investigate and quantify the effect of black tea consumption on serum concentrations of total, LDL and HDL cholesterol. METHODS: We systematically searched and identified relevant literatures in PubMed, Scopus and the Cochrane Library. Inclusion and exclusion of studies, data extraction, quality assessment and meta-analysis were conducted according to the PRISMA statement. RESULTS: Ten eligible studies with 411 participants were identified in the present meta-analysis. No significant heterogeneity was found between studies. Consumption of black tea significantly reduced LDL cholesterol concentration (-4.64 mg/dL; 95% CI: -8.99, -0.30 mg/dL; P = 0.036). No remarkable change was detected in total cholesterol (-2.04 mg/dL; 95% CI: -6.43, 2.35 mg/dL; P = 0.363) or HDL cholesterol (-1.15 mg/dL; 95% CI: -3.04, 0.75 mg/dL; P = 0.236). Subgroup analysis showed that the lowering effect on LDL cholesterol was more effective in subjects with higher cardiovascular risk. CONCLUSIONS: Black tea consumption significantly lowered serum concentration of LDL cholesterol, especially in subjects with higher cardiovascular risk. Black tea intake did not impose obvious effect on serum concentrations of total and HDL cholesterol.
BACKGROUND & AIMS: The results of randomized controlled trials in relation to the effect of regular black tea consumption on serum cholesterol concentration were inconsistent. We aimed to investigate and quantify the effect of black tea consumption on serum concentrations of total, LDL and HDL cholesterol. METHODS: We systematically searched and identified relevant literatures in PubMed, Scopus and the Cochrane Library. Inclusion and exclusion of studies, data extraction, quality assessment and meta-analysis were conducted according to the PRISMA statement. RESULTS: Ten eligible studies with 411 participants were identified in the present meta-analysis. No significant heterogeneity was found between studies. Consumption of black tea significantly reduced LDL cholesterol concentration (-4.64 mg/dL; 95% CI: -8.99, -0.30 mg/dL; P = 0.036). No remarkable change was detected in total cholesterol (-2.04 mg/dL; 95% CI: -6.43, 2.35 mg/dL; P = 0.363) or HDL cholesterol (-1.15 mg/dL; 95% CI: -3.04, 0.75 mg/dL; P = 0.236). Subgroup analysis showed that the lowering effect on LDL cholesterol was more effective in subjects with higher cardiovascular risk. CONCLUSIONS: Black tea consumption significantly lowered serum concentration of LDL cholesterol, especially in subjects with higher cardiovascular risk. Black tea intake did not impose obvious effect on serum concentrations of total and HDL cholesterol.
Authors: María-Teresa García-Conesa; Karen Chambers; Emilie Combet; Paula Pinto; Mar Garcia-Aloy; Cristina Andrés-Lacueva; Sonia de Pascual-Teresa; Pedro Mena; Alekxandra Konic Ristic; Wendy J Hollands; Paul A Kroon; Ana Rodríguez-Mateos; Geoffrey Istas; Christos A Kontogiorgis; Dilip K Rai; Eileen R Gibney; Christine Morand; Juan Carlos Espín; Antonio González-Sarrías Journal: Int J Mol Sci Date: 2018-02-28 Impact factor: 5.923
Authors: Chike C Nwabuo; Aisha S Betoko; Jared P Reis; Henrique T Moreira; Henrique D Vasconcellos; Eliseo Guallar; Christopher Cox; Stephen Sidney; Bharath Ambale-Venkatesh; Cora E Lewis; Pamela J Schreiner; Donald Lloyd-Jones; Catarina I Kiefe; Samuel S Gidding; João A C Lima Journal: ESC Heart Fail Date: 2020-05-25