BACKGROUND: Oxidative stress and dyslipidemia play a critical role in the development of cardiovascular disease (CVD). Regular intake of polyphenol-rich diets is associated with a reduced risk of CVDs. METHODS: The present study was a pilot study with 24 healthy volunteers and was designed to determine if a 12-week administration of Cistus incanus herbal tea, containing phenolic acids and flavonoids, reduces cardiovascular risk factors including oxidative stress and dyslipidemia in healthy adults. Phenolic compounds profile and antibacterial activity of Cistus incanus infusion were also measured. RESULTS: Herbal infusion led to improvement in lipid profile by increase (D4%, p = 0.033) high-density lipoprotein cholesterol concentration and decrease triglyceride (D14%, p = 0.013) concentrations. In addition, the Cistus incanus diet was associated with decreased serum concentrations of malondialdehyde (D16%, p < 0.01) and advanced oxidation protein products (D18%, p < 0.001). CONCLUSIONS: Cistus incanus administration decreases cardiovascular risk factors including oxidative stress and dyslipidemia and this action supports the idea of using Cistus incanus tea on a daily basis as an effective dietary component for prevention of atherosclerotic CVD.
BACKGROUND: Oxidative stress and dyslipidemia play a critical role in the development of cardiovascular disease (CVD). Regular intake of polyphenol-rich diets is associated with a reduced risk of CVDs. METHODS: The present study was a pilot study with 24 healthy volunteers and was designed to determine if a 12-week administration of Cistus incanus herbal tea, containing phenolic acids and flavonoids, reduces cardiovascular risk factors including oxidative stress and dyslipidemia in healthy adults. Phenolic compounds profile and antibacterial activity of Cistus incanus infusion were also measured. RESULTS: Herbal infusion led to improvement in lipid profile by increase (D4%, p = 0.033) high-density lipoprotein cholesterol concentration and decrease triglyceride (D14%, p = 0.013) concentrations. In addition, the Cistus incanus diet was associated with decreased serum concentrations of malondialdehyde (D16%, p < 0.01) and advanced oxidation protein products (D18%, p < 0.001). CONCLUSIONS:Cistus incanus administration decreases cardiovascular risk factors including oxidative stress and dyslipidemia and this action supports the idea of using Cistus incanus tea on a daily basis as an effective dietary component for prevention of atherosclerotic CVD.
Authors: B MacKness; M I Mackness; P N Durrington; S Arrol; A E Evans; D McMaster; J Ferrières; J B Ruidavets; N R Williams; A N Howard Journal: Eur J Clin Invest Date: 2000-01 Impact factor: 4.686
Authors: Miriam Martínez-Huélamo; Anna Vallverdú-Queralt; Giuseppe Di Lecce; Palmira Valderas-Martínez; Sara Tulipani; Olga Jáuregui; Elvira Escribano-Ferrer; Ramón Estruch; Montse Illan; Rosa M Lamuela-Raventós Journal: Mol Nutr Food Res Date: 2016-05-09 Impact factor: 5.914
Authors: Jordano Ferreira Reis; Valter Vinicius Silva Monteiro; Rafaelli de Souza Gomes; Matheus Moraes do Carmo; Glauber Vilhena da Costa; Paula Cardoso Ribera; Marta Chagas Monteiro Journal: J Transl Med Date: 2016-11-15 Impact factor: 5.531