Literature DB >> 24969420

Duration of urination does not change with body size.

Patricia J Yang1, Jonathan Pham1, Jerome Choo1, David L Hu2.   

Abstract

Many urological studies rely on models of animals, such as rats and pigs, but their relation to the human urinary system is poorly understood. Here, we elucidate the hydrodynamics of urination across five orders of magnitude in body mass. Using high-speed videography and flow-rate measurement obtained at Zoo Atlanta, we discover that all mammals above 3 kg in weight empty their bladders over nearly constant duration of 21 ± 13 s. This feat is possible, because larger animals have longer urethras and thus, higher gravitational force and higher flow speed. Smaller mammals are challenged during urination by high viscous and capillary forces that limit their urine to single drops. Our findings reveal that the urethra is a flow-enhancing device, enabling the urinary system to be scaled up by a factor of 3,600 in volume without compromising its function. This study may help to diagnose urinary problems in animals as well as inspire the design of scalable hydrodynamic systems based on those in nature.

Entities:  

Keywords:  Bernoulli's principle; allometry; scaling; urology

Mesh:

Year:  2014        PMID: 24969420      PMCID: PMC4143032          DOI: 10.1073/pnas.1402289111

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


  50 in total

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6.  Altered urinary bladder function in mice lacking the vanilloid receptor TRPV1.

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8.  Comparison of two experimental models of urodynamic evaluation in female rats.

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9.  Morphometry of the aging female rat urethra.

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Journal:  Int Urogynecol J Pelvic Floor Dysfunct       Date:  1996

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Authors:  Jon A Martin; Stan S Hillman
Journal:  Physiol Biochem Zool       Date:  2009 Mar-Apr       Impact factor: 2.247

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5.  Probabilistic, spinally-gated control of bladder pressure and autonomous micturition by Barrington's nucleus CRH neurons.

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Journal:  Elife       Date:  2020-04-29       Impact factor: 8.140

6.  A simple fluid dynamic model of renal pelvis pressures during ureteroscopic kidney stone treatment.

Authors:  Alexandros T Oratis; John J Subasic; Natalia Hernandez; James C Bird; Brian H Eisner
Journal:  PLoS One       Date:  2018-11-29       Impact factor: 3.240

7.  Oscillatory surface rheotaxis of swimming E. coli bacteria.

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Journal:  Nat Commun       Date:  2019-07-31       Impact factor: 14.919

8.  Characterization of mouse neuro-urological dynamics in a novel decerebrate arterially perfused mouse (DAPM) preparation.

Authors:  Hiroki Ito; Marcus J Drake; Christopher H Fry; Anthony J Kanai; Anthony E Pickering
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9.  The avian egg exhibits general allometric invariances in mechanical design.

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10.  Sexual dimorphism of detrusor function demonstrated by urodynamic studies in rhesus macaques.

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