Literature DB >> 24966358

Identification of occult Fusobacterium nucleatum central nervous system infection by use of PCR-electrospray ionization mass spectrometry.

Sudha Nagalingam1, Michelle Lisgaris1, Benigno Rodriguez1, Michael R Jacobs2, Michael Lederman1, Robert A Salata1, Andrea M Hujer3, Atis Muehlenbachs4, Marlene DeLeon-Carnes4, John J Farrell5, Rangarajan Sampath6, Robert A Bonomo7.   

Abstract

Anaerobic bacteria are often difficult to detect, especially after the initiation of antibiotics. We describe the application of PCR-electrospray ionization mass spectrometry (PCR/ESI-MS) using a sample of cerebrospinal fluid to identify an anaerobic Gram-negative bacillus, Fusobacterium nucleatum, in a patient with "culture-negative" meningitis and cerebral abscesses.
Copyright © 2014, American Society for Microbiology. All Rights Reserved.

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Year:  2014        PMID: 24966358      PMCID: PMC4313185          DOI: 10.1128/JCM.01082-14

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN: 0095-1137            Impact factor:   5.948


  8 in total

1.  Use of PCR coupled with electrospray ionization mass spectrometry for rapid identification of bacterial and yeast bloodstream pathogens from blood culture bottles.

Authors:  Erin J Kaleta; Andrew E Clark; Desiree R Johnson; Dulini C Gamage; Vicki H Wysocki; Abdessalam Cherkaoui; Jacques Schrenzel; Donna M Wolk
Journal:  J Clin Microbiol       Date:  2010-11-03       Impact factor: 5.948

Review 2.  Fusobacterial infections: clinical spectrum and incidence of invasive disease.

Authors:  Paul J Huggan; David R Murdoch
Journal:  J Infect       Date:  2008-09-20       Impact factor: 6.072

3.  New technology for rapid molecular diagnosis of bloodstream infections.

Authors:  David J Ecker; Rangarajan Sampath; Haijing Li; Christian Massire; Heather E Matthews; Donna Toleno; Thomas A Hall; Lawrence B Blyn; Mark W Eshoo; Raymond Ranken; Steven A Hofstadler; Yi-Wei Tang
Journal:  Expert Rev Mol Diagn       Date:  2010-05       Impact factor: 5.225

4.  Identification of Streptococcus intermedius central nervous system infection by use of PCR and electrospray ionization mass spectrometry.

Authors:  Nisha S Bhatia; John J Farrell; Rangarajan Sampath; Raymond Ranken; Megan A Rounds; David J Ecker; Robert A Bonomo
Journal:  J Clin Microbiol       Date:  2012-10-03       Impact factor: 5.948

5.  "Salvage microbiology": detection of bacteria directly from clinical specimens following initiation of antimicrobial treatment.

Authors:  John J Farrell; Rangarajan Sampath; David J Ecker; Robert A Bonomo
Journal:  PLoS One       Date:  2013-06-25       Impact factor: 3.240

6.  Characterization of polybacterial clinical samples using a set of group-specific broad-range primers targeting the 16S rRNA gene followed by DNA sequencing and RipSeq analysis.

Authors:  Øyvind Kommedal; Katrine Lekang; Nina Langeland; Harald G Wiker
Journal:  J Med Microbiol       Date:  2011-03-24       Impact factor: 2.472

Review 7.  Multiplex PCR and emerging technologies for the detection of respiratory pathogens.

Authors:  Angela M Caliendo
Journal:  Clin Infect Dis       Date:  2011-05       Impact factor: 9.079

Review 8.  Rapid identification of emerging infectious agents using PCR and electrospray ionization mass spectrometry.

Authors:  Rangarajan Sampath; Thomas A Hall; Christian Massire; Feng Li; Lawrence B Blyn; Mark W Eshoo; Steven A Hofstadler; David J Ecker
Journal:  Ann N Y Acad Sci       Date:  2007-04       Impact factor: 5.691

  8 in total
  3 in total

1.  Primary meningitis due to Fusobacterium nucleatum successfully treated with ceftriaxone in a healthy adult male.

Authors:  Trager Hintze; Michelle Steed; Eric Sievers; John T Bagwell; Nicola Selfa
Journal:  IDCases       Date:  2019-08-05

2.  Brain Abscess: A Rare Clinical Case with Oral Etiology.

Authors:  André João da Silva Pais Rocha Pereira; Ana Teresa Tavares; Marcelo Prates; Natacha Ribeiro; Luís Filipe Fonseca; Maria do Rosário Marques; Francisco Proença
Journal:  Case Rep Infect Dis       Date:  2022-01-04

3.  Case report: Meningitis and intracranial aneurysm caused by mixed infection of oral microflora dominated by anaerobes.

Authors:  Hongjiang Cheng; Lina Xu; Fengbing Yang; Longbin Jia; Doudou Zhao; Huimin Li; Wei Liu; Yujuan Li; Xiaoli Liu; Xia Geng; Jiaying Guo; Chen Ling; Jing Zhang
Journal:  Front Neurol       Date:  2022-08-05       Impact factor: 4.086

  3 in total

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