Literature DB >> 24965007

Determination of phthalates and their by-products in tissues of roach (Rutilus rutilus) from the Orge river (France).

A S Valton1, C Serre-Dargnat, M Blanchard, F Alliot, M Chevreuil, Marie Jeanne Teil.   

Abstract

Seven phthalate by-products were investigated for the first time, in target tissues of roach from a contaminated river of the Ile-de-France district. All parent phthalates were bioaccumulated in liver and muscle and liver contents were correlated with river concentrations (p < 0.01). All metabolites were found in liver, plasma and bile. The mono-iso-butyl phthalate (MiBP; 1.6 μg g(-1) dw of liver), followed by mono-n-butyl phthalate (MnBP; 1.5 μg g(-1) dw of liver) were the most abundant ones. Among the three metabolites of di-ethylhexyl phthalate (DEHP), mono (2-ethylhexyl) phthalate (MEHP) predominated in bile (15.5 ng ml(-1)) and liver (0.237 μg g(-1) dw), whereas in plasma, it was mono (2-ethyl-5-hydroxyhexyl) phthalate - MEHHP (214 ng ml(-1)). In liver, MEHP/DEHP ratios ranged from 0.04 to 0.2. Among the oxidized metabolites, only mono (2-ethyl-5-oxohexyl) phthalate (MEOHP) was correlated (p < 0.05) with parent DEHP and appeared to be a more reliable marker of DEHP impact than the monoester.

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Year:  2014        PMID： 24965007     DOI： 10.1007/s11356-014-3213-0

Source DB:  PubMed          Journal:  Environ Sci Pollut Res Int        ISSN： 0944-1344            Impact factor:   4.223


  18 in total

1.  Quantitative detection of eight phthalate metabolites in human urine using HPLC-APCI-MS/MS.

Authors:  B C Blount; K E Milgram; M J Silva; N A Malek; J A Reidy; L L Needham; J W Brock
Journal:  Anal Chem       Date:  2000-09-01       Impact factor: 6.986

2.  Determination of phthalate monoesters in human milk, consumer milk, and infant formula by tandem mass spectrometry (LC-MS-MS).

Authors:  Gerda K Mortensen; Katharina M Main; Anna-Maria Andersson; Henrik Leffers; Niels E Skakkebaek
Journal:  Anal Bioanal Chem       Date:  2005-06-03       Impact factor: 4.142

3.  [Substance monograph for phthalates - New and updated reference and oxidized monoester metabolites in urine of children-and adults. Opinion of the Commission "Human-Biomonitoring" by the Federal Environment Agency].

Authors: 
Journal:  Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz       Date:  2011-06       Impact factor: 1.513

4.  Occurrence of polybrominated diphenyl ethers, polychlorinated biphenyls, and phthalates in freshwater fish from the Orge river (Ile-de France).

Authors:  Marie-Jeanne Teil; Khawla Tlili; Martine Blanchard; Marc Chevreuil; Fabrice Alliot; Pierre Labadie
Journal:  Arch Environ Contam Toxicol       Date:  2012-01-11       Impact factor: 2.804

5.  Correlations between phthalate metabolites in urine, serum, and seminal plasma from young Danish men determined by isotope dilution liquid chromatography tandem mass spectrometry.

Authors:  Hanne Frederiksen; Niels Jørgensen; Anna-Maria Andersson
Journal:  J Anal Toxicol       Date:  2010-09       Impact factor: 3.367

6.  Glucuronidation patterns of common urinary and serum monoester phthalate metabolites.

Authors:  Manori J Silva; Dana B Barr; John A Reidy; Kayoko Kato; Nicole A Malek; Carolyn C Hodge; Donald Hurtz; Antonia M Calafat; Larry L Needham; John W Brock
Journal:  Arch Toxicol       Date:  2003-06-28       Impact factor: 5.153

7.  Blood burden of di(2-ethylhexyl) phthalate and its primary metabolite mono(2-ethylhexyl) phthalate in pregnant and nonpregnant rats and marmosets.

Authors:  Winfried Kessler; Wanwiwa Numtip; Konstanze Grote; György A Csanády; Ibrahim Chahoud; Johannes G Filser
Journal:  Toxicol Appl Pharmacol       Date:  2004-03-01       Impact factor: 4.219

8.  Validation and application of an HPLC method for determination of di (2-ethylhexyl) phthalate and mono (2-ethylhexyl) phthalate in liver samples.

Authors:  Debajit Sircar; Sargon J Albazi; Yousef Atallah; William Pizzi
Journal:  J Chromatogr Sci       Date:  2008-08       Impact factor: 1.618

9.  Metabolite profiles of di-n-butyl phthalate in humans and rats.

Authors:  Manori J Silva; Ella Samandar; John A Reidy; Russ Hauser; Larry L Needham; Antonia M Calafat
Journal:  Environ Sci Technol       Date:  2007-11-01       Impact factor: 9.028

10.  In utero exposure to di-(2-ethylhexyl)phthalate and duration of human pregnancy.

Authors:  Giuseppe Latini; Claudio De Felice; Giuseppe Presta; Antonio Del Vecchio; Irma Paris; Fabrizio Ruggieri; Pietro Mazzeo
Journal:  Environ Health Perspect       Date:  2003-11       Impact factor: 9.031
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  4 in total

1.  Phthalate pollution in an Amazonian rainforest.

Authors:  Alain Lenoir; Raphaël Boulay; Alain Dejean; Axel Touchard; Virginie Cuvillier-Hot
Journal:  Environ Sci Pollut Res Int       Date:  2016-07-02       Impact factor: 4.223

2.  Demographic Assessment of Mono(2-ethylhexyl) Phthalate (MEHP) and Monoethyl Phthalate (MEP) Concentrations in Common Bottlenose Dolphins (Tursiops truncatus) From Sarasota Bay, FL, USA.

Authors:  M K Dziobak; R S Wells; E C Pisarski; E F Wirth; L B Hart
Journal:  Geohealth       Date:  2021-05-01

3.  Urinary Phthalate Metabolites in Common Bottlenose Dolphins (Tursiops truncatus) From Sarasota Bay, FL, USA.

Authors:  Leslie B Hart; Barbara Beckingham; Randall S Wells; Moriah Alten Flagg; Kerry Wischusen; Amanda Moors; John Kucklick; Emily Pisarski; Ed Wirth
Journal:  Geohealth       Date:  2018-10-20

4.  Sentinels of synthetics - a comparison of phthalate exposure between common bottlenose dolphins (Tursiops truncatus) and human reference populations.

Authors:  Leslie B Hart; Miranda K Dziobak; Emily C Pisarski; Edward F Wirth; Randall S Wells
Journal:  PLoS One       Date:  2020-10-15       Impact factor: 3.240
  4 in total

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