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Literature DB >> 24964963

Podoplanin--a novel marker in oral carcinogenesis.

Niharika Swain¹, Shwetha V Kumar, Samapika Routray, Jigna Pathak, Shilpa Patel.

Abstract

Podoplanin, a transmembrane sialoglycoprotein, is a specific marker for lymphatic endothelial cells which in recent years has gained prominent notoriety for its role in tumor progression and metastasis. It is an extensively studied biomarker for predictive assessment of malignant transformation as well as biologic behavior in both human precancer and cancer, respectively. This review summarizes the association of podoplanin overexpression in oral potentially malignant disorders and oral cancer with special emphasis on its putative role in carcinogenesis as well as its prospective use in targeted therapy.

Entities: Disease Gene Species

Mesh：

Substances：

Year: 2014 PMID： 24964963 DOI： 10.1007/s13277-014-2266-5

Source DB: PubMed Journal: Tumour Biol ISSN： 1010-4283

62 in total

1. Novel function for blood platelets and podoplanin in developmental separation of blood and lymphatic circulation.

Authors: Pavel Uhrin; Jan Zaujec; Johannes M Breuss; Damla Olcaydu; Peter Chrenek; Hannes Stockinger; Elke Fuertbauer; Markus Moser; Paula Haiko; Reinhard Fässler; Kari Alitalo; Bernd R Binder; Dontscho Kerjaschki
Journal: Blood Date: 2010-01-28 Impact factor: 22.113

2. Podoplanin and VEGF-C immunoexpression in oral squamous cell carcinomas: prognostic significance.

Authors: Aroldo dos Santos Almeida; Denise Tostes Oliveira; Michele Conceição Pereira; Simone Eloiza Sita Faustino; Suely Nonogaki; André Lopes Carvalho; Luiz Paulo Kowalski
Journal: Anticancer Res Date: 2013-09 Impact factor: 2.480

3. Enhanced expression of podoplanin in oral carcinomas in situ and squamous cell carcinomas.

Authors: Akinori Funayama; Jun Cheng; Satoshi Maruyama; Manabu Yamazaki; Takanori Kobayashi; Mei Syafriadi; Sukalyan Kundu; Susumu Shingaki; Chikara Saito; Takashi Saku
Journal: Pathobiology Date: 2011-05-26 Impact factor: 4.342

4. Podoplanin and ABCG2: malignant transformation risk markers for oral lichen planus.

Authors: Peng Shi; Wei Liu; Zeng-Tong Zhou; Qing-Bo He; Wei-Wen Jiang
Journal: Cancer Epidemiol Biomarkers Prev Date: 2010-03-03 Impact factor: 4.254

5. Expression of podoplanin and ABCG2 in oral erythroplakia correlate with oral cancer development.

Authors: Jin-Qiu Feng; Jun-Guo Mi; Lan Wu; Li-Wei Ma; Lin-Jun Shi; Xi Yang; Wei Liu; Chen-Ping Zhang; Zeng-Tong Zhou
Journal: Oral Oncol Date: 2012-04-22 Impact factor: 5.337

6. Lymphangiogenesis and podoplanin expression in oral squamous cell carcinoma and the associated lymph nodes.

Authors: Sílvia Ferreira de Sousa; Frederico Omar Gleber-Netto; Helenisa Helena de Oliveira-Neto; Aline Carvalho Batista; Mauro Henrique Nogueira Guimarães Abreu; Maria Cássia Ferreira de Aguiar
Journal: Appl Immunohistochem Mol Morphol Date: 2012-12

7. Podoplanin (D2-40) is a novel marker for follicular dendritic cell tumors.

Authors: Hongbo Yu; Joanna A Gibson; Geraldine S Pinkus; Jason L Hornick
Journal: Am J Clin Pathol Date: 2007-11 Impact factor: 2.493

8. Immunohistochemical examination for the distribution of podoplanin-expressing cells in developing mouse molar tooth germs.

Authors: Yuri Imaizumi; Ikuko Amano; Eichi Tsuruga; Hiroshi Kojima; Yoshihiko Sawa
Journal: Acta Histochem Cytochem Date: 2010-10-15 Impact factor: 1.938

Review 9. The role of podoplanin in tumor progression and metastasis.

Authors: Marius Raica; Anca Maria Cimpean; Domenico Ribatti
Journal: Anticancer Res Date: 2008 Sep-Oct Impact factor: 2.480

10. Involvement of the snake toxin receptor CLEC-2, in podoplanin-mediated platelet activation, by cancer cells.

Authors: Katsue Suzuki-Inoue; Yukinari Kato; Osamu Inoue; Mika Kato Kaneko; Kazuhiko Mishima; Yutaka Yatomi; Yasuo Yamazaki; Hisashi Narimatsu; Yukio Ozaki
Journal: J Biol Chem Date: 2007-07-06 Impact factor: 5.157

7 in total

1. High relative density of lymphatic vessels predicts poor survival in tongue squamous cell carcinoma.

Authors: Miia Seppälä; Konsta Pohjola; Jussi Laranne; Markus Rautiainen; Heini Huhtala; Risto Renkonen; Karl Lemström; Timo Paavonen; Sanna Toppila-Salmi
Journal: Eur Arch Otorhinolaryngol Date: 2016-06-21 Impact factor: 2.503

2. Antibody and lectin target podoplanin to inhibit oral squamous carcinoma cell migration and viability by distinct mechanisms.

Authors: Jhon A Ochoa-Alvarez; Harini Krishnan; John G Pastorino; Evan Nevel; David Kephart; Joseph J Lee; Edward P Retzbach; Yongquan Shen; Mahnaz Fatahzadeh; Soly Baredes; Evelyne Kalyoussef; Masaru Honma; Martin E Adelson; Mika K Kaneko; Yukinari Kato; Mary Ann Young; Lisa Deluca-Rapone; Alan J Shienbaum; Kingsley Yin; Lasse D Jensen; Gary S Goldberg
Journal: Oncotarget Date: 2015-04-20

Review 3. Podoplanin: An emerging cancer biomarker and therapeutic target.

Authors: Harini Krishnan; Julie Rayes; Tomoyuki Miyashita; Genichiro Ishii; Edward P Retzbach; Stephanie A Sheehan; Ai Takemoto; Yao-Wen Chang; Kazue Yoneda; Jun Asai; Lasse Jensen; Lushun Chalise; Atsushi Natsume; Gary S Goldberg
Journal: Cancer Sci Date: 2018-05 Impact factor: 6.716

Review 7. Prognostic and Clinicopathological Significance of the Aberrant Expression of β-Catenin in Oral Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis.

Authors: Pablo Ramos-García; Miguel Á González-Moles
Journal: Cancers (Basel) Date: 2022-01-18 Impact factor: 6.639