| Literature DB >> 24955432 |
Michael I Miller1, Laurent Younes2, J Tilak Ratnanather3, Timothy Brown4, Tommy Reigel5, Huong Trinh6, Xiaoying Tang, Peter Barker, Susumu Mori, Marilyn Albert.
Abstract
Surface-based deformation markers obtained from diffeomorphic mapping of the amygdala are used to study specific atrophy patterns in a combined mild cognitively impaired and demented cohort compared with cognitively normal aging subjects. Statistical analysis demonstrates with high significance in a small sample of legacy data that deformation-based morphometry provides sensitive markers for locating atrophy in the amygdala. With respect to a high-field amygdala atlas, significant atrophy was found in the basomedial and lateral nucleus subregions.Entities:
Year: 2012 PMID: 24955432 PMCID: PMC4063307
Source DB: PubMed Journal: Med Image Comput Comput Assist Interv