Mihir Patel1, Estela Staggs2, Colleen S Thomas3, Frank Lukens1, Michael Wallace1, Cristina Almansa4. 1. Department of Gastroenterology, Mayo Clinic, Jacksonville, FL, USA. 2. General Clinical Studies Unit, Mayo Clinic, Jacksonville, FL, USA. 3. Department of Health Sciences Research, Mayo Clinic, Jacksonville, FL, USA. 4. Department of Gastroenterology, Mayo Clinic, Jacksonville, FL, USA. Electronic address: almansa.cristina@mayo.edu.
Abstract
BACKGROUND: Bowel cleansing is paramount for colonoscopy quality. Unfortunately, an adequate bowel preparation is often limited by side effects and/or patient's intolerance to bowel preparation solutions. Comparisons among different preparations are limited by the lack of validated instruments designed to assess patient's tolerability. AIM: To develop and validate a simple, comprehensive instrument to assess bowel preparation tolerability in patients undergoing colonoscopy. METHODS: Development and validation by phases: Phase I (bibliographic search and questionnaire design); Phase II (assessment of content validity and modification of the questionnaire); Phase III (assessment of reproducibility, final validation, and definitive version of the questionnaire). RESULTS: The initial draft of the questionnaire was generated based on a systematic literature review and feedback from a panel of consultants. Content validity was tested in a focus group of 25 patients undergoing colonoscopy. Patients' suggestions were reviewed by the research team and a second draft of the questionnaire was generated. Final validation and reproducibility were successfully tested (agreement: 86-100%, kappa: 0.77-1.00) in a convenience sample of 100 patients undergoing bowel preparation with different cleansing solutions. CONCLUSION: The Mayo Clinic Bowel Prep Tolerability Questionnaire is a simple, comprehensive instrument suitable to evaluate the tolerability of various types of bowel preparations.
BACKGROUND: Bowel cleansing is paramount for colonoscopy quality. Unfortunately, an adequate bowel preparation is often limited by side effects and/or patient's intolerance to bowel preparation solutions. Comparisons among different preparations are limited by the lack of validated instruments designed to assess patient's tolerability. AIM: To develop and validate a simple, comprehensive instrument to assess bowel preparation tolerability in patients undergoing colonoscopy. METHODS: Development and validation by phases: Phase I (bibliographic search and questionnaire design); Phase II (assessment of content validity and modification of the questionnaire); Phase III (assessment of reproducibility, final validation, and definitive version of the questionnaire). RESULTS: The initial draft of the questionnaire was generated based on a systematic literature review and feedback from a panel of consultants. Content validity was tested in a focus group of 25 patients undergoing colonoscopy. Patients' suggestions were reviewed by the research team and a second draft of the questionnaire was generated. Final validation and reproducibility were successfully tested (agreement: 86-100%, kappa: 0.77-1.00) in a convenience sample of 100 patients undergoing bowel preparation with different cleansing solutions. CONCLUSION: The Mayo Clinic Bowel Prep Tolerability Questionnaire is a simple, comprehensive instrument suitable to evaluate the tolerability of various types of bowel preparations.
Authors: Ala I Sharara; Hamza Daroub; Camille Georges; Rani Shayto; Ralph Nader; Jean Chalhoub; Ammar Olabi Journal: World J Gastrointest Endosc Date: 2016-08-10
Authors: Ala I Sharara; Zeinab D El Reda; Ali H Harb; Carla G Abou Fadel; Fayez S Sarkis; Jean M Chalhoub; Rachel Abou Mrad Journal: United European Gastroenterol J Date: 2015-07-03 Impact factor: 4.623
Authors: Lawrence Hookey; Gerald Bertiger; Kenneth Lee Johnson; Julia Ayala; Yodit Seifu; Stuart P Brogadir Journal: Therap Adv Gastroenterol Date: 2019-05-19 Impact factor: 4.409
Authors: Lawrence Hookey; Gerald Bertiger; Kenneth Lee Johnson; Mena Boules; Masakazu Ando; David N Dahdal Journal: Therap Adv Gastroenterol Date: 2020-04-09 Impact factor: 4.409
Authors: Dale R Bachwich; James D Lewis; Vera O Kowal; Brian C Jacobson; Audrey H Calderwood; Michael L Kochman Journal: Clin Transl Gastroenterol Date: 2020-12 Impact factor: 4.396
Authors: Gabriel Perreault; Adam Goodman; Sebastian Larion; Ahana Sen; Kirsten Quiles; Michael Poles; Renee Williams Journal: Ann Gastroenterol Date: 2018-03-28
Authors: Lawrence Hookey; Gerald Bertiger; Kenneth Lee Johnson; Mena Boules; Masakazu Ando; David N Dahdal Journal: Therap Adv Gastroenterol Date: 2020-02-07 Impact factor: 4.409