José L Zamorano1, Xavier García-Moll2, Roberto Ferrari3, Nicola Greenlaw4. 1. Servicio de Cardiología, Hospital Universitario Ramón y Cajal, Madrid, Spain. Electronic address: zamorano@secardiologia.es. 2. Servicio de Cardiología, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain. 3. Servicio de Cardiología, Hospital Universitario de Ferrara, Ferrara, Italy. 4. Robertson Centre for Biostatistics, University of Glasgow, Glasgow, United Kingdom.
Abstract
INTRODUCTION AND OBJECTIVES: Coronary artery disease is associated with high morbidity and mortality. The objective of the CLARIFY registry is to study the treatment of outpatients with coronary artery disease in the setting of daily clinical practice. METHODS: The CLARIFY registry is a prospective registry conducted in 41 countries that included outpatients with stable coronary artery disease attending primary care or specialist units between October 2009 and June 2010. The present study describes the baseline characteristics of the Spanish cohort compared with the western European cohorts included in the registry. RESULTS: A total of 33,248 patients were included: 14,726 in western Europe and 2257 in Spain (selected by 192 cardiologists). The majority of the participants in Spain were men (81%) with a mean age of 65 years. There was a higher frequency of diabetes (34% vs 25%; P<.0001), coronary artery disease family history (19% vs 31%; P<.0001), myocardial infarction (64% vs 60%; P<.0001), and stroke (5% vs 3%; P=.0007) in the Spanish cohort than in the western European cohorts. The most common treatments in the Spanish sample were lipid-lowering drugs (96%), acetylsalicylic acid (89%), and beta-blockers (74%). CONCLUSIONS: Patients in the Spanish cohort are similar to those in the western European cohorts and seem to be representative of the Spanish population with coronary artery disease. Therefore, they form a suitable basis for the study of prognostic factors at 5-year follow-up.
INTRODUCTION AND OBJECTIVES:Coronary artery disease is associated with high morbidity and mortality. The objective of the CLARIFY registry is to study the treatment of outpatients with coronary artery disease in the setting of daily clinical practice. METHODS: The CLARIFY registry is a prospective registry conducted in 41 countries that included outpatients with stable coronary artery disease attending primary care or specialist units between October 2009 and June 2010. The present study describes the baseline characteristics of the Spanish cohort compared with the western European cohorts included in the registry. RESULTS: A total of 33,248 patients were included: 14,726 in western Europe and 2257 in Spain (selected by 192 cardiologists). The majority of the participants in Spain were men (81%) with a mean age of 65 years. There was a higher frequency of diabetes (34% vs 25%; P<.0001), coronary artery disease family history (19% vs 31%; P<.0001), myocardial infarction (64% vs 60%; P<.0001), and stroke (5% vs 3%; P=.0007) in the Spanish cohort than in the western European cohorts. The most common treatments in the Spanish sample were lipid-lowering drugs (96%), acetylsalicylic acid (89%), and beta-blockers (74%). CONCLUSIONS:Patients in the Spanish cohort are similar to those in the western European cohorts and seem to be representative of the Spanish population with coronary artery disease. Therefore, they form a suitable basis for the study of prognostic factors at 5-year follow-up.
Authors: Christian Roth; Clemens Gangl; Daniel Dalos; Lisa Krenn; Sabine Scherzer; Anna Gerken; Martin Reinwein; Chao Zhang; Michael Hagmann; Thomas Wrba; Georg Delle-Karth; Thomas Neunteufl; Gerald Maurer; Paul Vock; Harald Mayr; Bernhard Frey; Rudolf Berger Journal: PLoS One Date: 2016-04-22 Impact factor: 3.240
Authors: Francisco Javier Félix-Redondo; Luis Lozano Mera; Luciano Consuegra-Sánchez; Fernando Giménez Sáez; Francisco Javier Garcipérez de Vargas; José María Castellano Vázquez; Daniel Fernández-Bergés Journal: Open Heart Date: 2016-02-26