Literature DB >> 24951816

Murine spleen tissue regeneration from neonatal spleen capsule requires lymphotoxin priming of stromal cells.

Jonathan K H Tan1, Takeshi Watanabe2.   

Abstract

Spleen is a tissue with regenerative capacity, which allows autotransplantation of human spleen fragments to counteract the effects of splenectomy. We now reveal in a murine model that transplant of neonatal spleen capsule alone leads to the regeneration of full spleen tissue. This finding indicates that graft-derived spleen stromal cells, but not lymphocytes, are essential components of tissue neogenesis, a finding verified by transplant and regeneration of Rag1KO spleen capsules. We further demonstrate that lymphotoxin and lymphoid tissue inducer cells participate in two key elements of spleen neogenesis, bulk tissue regeneration and white pulp organization, identifying a lymphotoxin-dependent pathway for neonatal spleen regeneration that contrasts with previously defined lymphotoxin-independent embryonic spleen organogenesis.
Copyright © 2014 by The American Association of Immunologists, Inc.

Entities:  

Mesh：

Substances：

Year:  2014        PMID： 24951816      PMCID： PMC4105237          DOI： 10.4049/jimmunol.1302115

Source DB:  PubMed          Journal:  J Immunol        ISSN： 0022-1767            Impact factor:   5.422


  32 in total

Review 1.  Development and function of the mammalian spleen.

Authors:  Andrea Brendolan; Maria Manuela Rosado; Rita Carsetti; Licia Selleri; T Neil Dear
Journal:  Bioessays       Date:  2007-02       Impact factor: 4.345

2.  The role of lymphoid tissue inducer cells in splenic white pulp development.

Authors:  David R Withers; Mi-Yeon Kim; Vasileios Bekiaris; Simona W Rossi; William E Jenkinson; Fabrina Gaspal; Fiona McConnell; Jorge H Caamano; Graham Anderson; Peter J L Lane
Journal:  Eur J Immunol       Date:  2007-11       Impact factor: 5.532

3.  Separation of splenic red and white pulp occurs before birth in a LTalphabeta-independent manner.

Authors:  Mark F R Vondenhoff; Guillaume E Desanti; Tom Cupedo; Julien Y Bertrand; Ana Cumano; Georg Kraal; Reina E Mebius; Rachel Golub
Journal:  J Leukoc Biol       Date:  2008-04-10       Impact factor: 4.962

4.  Restoration of lymphoid organ integrity through the interaction of lymphoid tissue-inducer cells with stroma of the T cell zone.

Authors:  Elke Scandella; Beatrice Bolinger; Evelyn Lattmann; Simone Miller; Stéphanie Favre; Dan R Littman; Daniela Finke; Sanjiv A Luther; Tobias Junt; Burkhard Ludewig
Journal:  Nat Immunol       Date:  2008-04-20       Impact factor: 25.606

Review 5.  Spleen autotransplantation. Morphological and functional follow-up after spleen autotransplantation in mice: a research summary.

Authors:  Iren Miko; Endre Brath; Norbert Nemeth; Andrea Furka; Sandor Sipka; Katalin Peto; Jozsef Serfozo; Judit Kovacs; Sandor Imre; Ilona Benko; Laszlo Galuska; Sandor Sipka; Geza Acs; Istvan Furka
Journal:  Microsurgery       Date:  2007       Impact factor: 2.425

6.  Regeneration of implanted splenic tissue in the rat: re-innervation is host age-dependent and necessary for tissue development.

Authors:  J Westermann; S Michel; S Lopez-Kostka; U Bode; H J Rothkötter; M Bette; E Weihe; R H Straub; R Pabst
Journal:  J Neuroimmunol       Date:  1998-08-01       Impact factor: 3.478

7.  Fibroblastic reticular cells in lymph nodes regulate the homeostasis of naive T cells.

Authors:  Alexander Link; Tobias K Vogt; Stéphanie Favre; Mirjam R Britschgi; Hans Acha-Orbea; Boris Hinz; Jason G Cyster; Sanjiv A Luther
Journal:  Nat Immunol       Date:  2007-09-23       Impact factor: 25.606

8.  Tissue-engineered spleen protects against overwhelming pneumococcal sepsis in a rodent model.

Authors:  Tracy C Grikscheit; Frédéric G Sala; Jennifer Ogilvie; Kate A Bower; Erin R Ochoa; Eben Alsberg; David Mooney; Joseph P Vacanti
Journal:  J Surg Res       Date:  2008-02-15       Impact factor: 2.192

9.  The lymphotoxin beta receptor controls organogenesis and affinity maturation in peripheral lymphoid tissues.

Authors:  A Fütterer; K Mink; A Luz; M H Kosco-Vilbois; K Pfeffer
Journal:  Immunity       Date:  1998-07       Impact factor: 31.745

10.  Organizer-like reticular stromal cell layer common to adult secondary lymphoid organs.

Authors:  Tomoya Katakai; Hidenori Suto; Manabu Sugai; Hiroyuki Gonda; Atsushi Togawa; Sachiko Suematsu; Yukihiko Ebisuno; Koko Katagiri; Tatsuo Kinashi; Akira Shimizu
Journal:  J Immunol       Date:  2008-11-01       Impact factor: 5.422
View more
  11 in total

1.  CXCL13 responsiveness but not CXCR5 expression by late transitional B cells initiates splenic white pulp formation.

Authors:  Harold R Neely; Martin F Flajnik
Journal:  J Immunol       Date:  2015-02-06       Impact factor: 5.422

Review 2.  Spleen: Reparative Regeneration and Influence on Liver.

Authors:  Andrey Elchaninov; Polina Vishnyakova; Gennady Sukhikh; Timur Fatkhudinov
Journal:  Life (Basel)       Date:  2022-04-22

3.  Roles of the mitochondrial Na(+)-Ca(2+) exchanger, NCLX, in B lymphocyte chemotaxis.

Authors:  Bongju Kim; Ayako Takeuchi; Masaki Hikida; Satoshi Matsuoka
Journal:  Sci Rep       Date:  2016-06-22       Impact factor: 4.379

Review 4.  Determinants of postnatal spleen tissue regeneration and organogenesis.

Authors:  Jonathan K H Tan; Takeshi Watanabe
Journal:  NPJ Regen Med       Date:  2018-01-16

5.  Stromal Cell Subsets Directing Neonatal Spleen Regeneration.

Authors:  Jonathan K H Tan; Takeshi Watanabe
Journal:  Sci Rep       Date:  2017-01-09       Impact factor: 4.379

Review 6.  Innate Lymphoid Cells in the Maternal and Fetal Compartments.

Authors:  Derek Miller; Kenichiro Motomura; Valeria Garcia-Flores; Roberto Romero; Nardhy Gomez-Lopez
Journal:  Front Immunol       Date:  2018-10-26       Impact factor: 7.561

7.  Identification of Stromal Cells in Spleen Which Support Myelopoiesis.

Authors:  Hong Kiat Lim; Helen C O'Neill
Journal:  Front Cell Dev Biol       Date:  2019-01-24

Review 8.  Innate Lymphoid Cells in Human Pregnancy.

Authors:  João Mendes; Ana Luísa Areia; Paulo Rodrigues-Santos; Manuel Santos-Rosa; Anabela Mota-Pinto
Journal:  Front Immunol       Date:  2020-11-30       Impact factor: 7.561

Review 9.  Lymphotoxin: from the physiology to the regeneration of the thymic function.

Authors:  Alexia Borelli; Magali Irla
Journal:  Cell Death Differ       Date:  2021-07-22       Impact factor: 12.067

10.  Transplanted spleen stromal cells with osteogenic potential support ectopic myelopoiesis.

Authors:  Helen C O'Neill; Hong K Lim; Pravin Periasamy; Lavanya Kumarappan; Jonathan K H Tan; Terence J O'Neill
Journal:  PLoS One       Date:  2019-10-04       Impact factor: 3.240
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.