Literature DB >> 24950375

Nuclear PI5P, Uhrf1, and the road not taken.

Nicolas Reynoird1, Or Gozani2.   

Abstract

In this issue of Molecular Cell, Gelato et al. (2014) identify the signaling molecule phosphatidylinositol 5-phosphate (PI5P) as an allosteric regulator that determines the mode of chromatin binding for the DNA methylation maintenance factor Uhrf1. This work links nuclear lipids to chromatin signaling in the maintenance of DNA methylation and epigenetic regulation.
Copyright © 2014 Elsevier Inc. All rights reserved.

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Year:  2014        PMID： 24950375      PMCID： PMC4123760          DOI： 10.1016/j.molcel.2014.06.012

Source DB:  PubMed          Journal:  Mol Cell        ISSN： 1097-2765            Impact factor:   17.970


  9 in total

1.  UHRF1 plays a role in maintaining DNA methylation in mammalian cells.

Authors:  Magnolia Bostick; Jong Kyong Kim; Pierre-Olivier Estève; Amander Clark; Sriharsa Pradhan; Steven E Jacobsen
Journal:  Science       Date:  2007-08-02       Impact factor: 47.728

Review 2.  Nuclear phosphoinositides and their impact on nuclear functions.

Authors:  Zahid H Shah; David R Jones; Lilly Sommer; Rebecca Foulger; Yvette Bultsma; Clive D'Santos; Nullin Divecha
Journal:  FEBS J       Date:  2013-10-21       Impact factor: 5.542

3.  Uhrf1-dependent H3K23 ubiquitylation couples maintenance DNA methylation and replication.

Authors:  Atsuya Nishiyama; Luna Yamaguchi; Jafar Sharif; Yoshikazu Johmura; Takeshi Kawamura; Keiko Nakanishi; Shintaro Shimamura; Kyohei Arita; Tatsuhiko Kodama; Fuyuki Ishikawa; Haruhiko Koseki; Makoto Nakanishi
Journal:  Nature       Date:  2013-09-08       Impact factor: 49.962

4.  The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA.

Authors:  Jafar Sharif; Masahiro Muto; Shin-ichiro Takebayashi; Isao Suetake; Akihiro Iwamatsu; Takaho A Endo; Jun Shinga; Yoko Mizutani-Koseki; Tetsuro Toyoda; Kunihiro Okamura; Shoji Tajima; Kohzoh Mitsuya; Masaki Okano; Haruhiko Koseki
Journal:  Nature       Date:  2007-11-11       Impact factor: 49.962

5.  Accessibility of different histone H3-binding domains of UHRF1 is allosterically regulated by phosphatidylinositol 5-phosphate.

Authors:  Kathy A Gelato; Maria Tauber; Michelle S Ong; Stefan Winter; Kyoko Hiragami-Hamada; Julia Sindlinger; Alexander Lemak; Yvette Bultsma; Scott Houliston; Dirk Schwarzer; Nullin Divecha; Cheryl H Arrowsmith; Wolfgang Fischle
Journal:  Mol Cell       Date:  2014-05-08       Impact factor: 17.970

6.  ICBP90, a novel methyl K9 H3 binding protein linking protein ubiquitination with heterochromatin formation.

Authors:  Panagiota Karagianni; Larbi Amazit; Jun Qin; Jiemin Wong
Journal:  Mol Cell Biol       Date:  2007-10-29       Impact factor: 4.272

7.  UHRF1 targets DNMT1 for DNA methylation through cooperative binding of hemi-methylated DNA and methylated H3K9.

Authors:  Xiaoli Liu; Qinqin Gao; Pishun Li; Qian Zhao; Jiqin Zhang; Jiwen Li; Haruhiko Koseki; Jiemin Wong
Journal:  Nat Commun       Date:  2013       Impact factor: 14.919

8.  Multivalent histone engagement by the linked tandem Tudor and PHD domains of UHRF1 is required for the epigenetic inheritance of DNA methylation.

Authors:  Scott B Rothbart; Bradley M Dickson; Michelle S Ong; Krzysztof Krajewski; Scott Houliston; Dmitri B Kireev; Cheryl H Arrowsmith; Brian D Strahl
Journal:  Genes Dev       Date:  2013-06-01       Impact factor: 11.361

9.  The PHD finger of human UHRF1 reveals a new subgroup of unmethylated histone H3 tail readers.

Authors:  Nada Lallous; Pierre Legrand; Alastair G McEwen; Santiago Ramón-Maiques; Jean-Pierre Samama; Catherine Birck
Journal:  PLoS One       Date:  2011-11-11       Impact factor: 3.240
  9 in total
  1 in total

1.  Combined Action of Histone Reader Modules Regulates NuA4 Local Acetyltransferase Function but Not Its Recruitment on the Genome.

Authors:  Anne-Lise Steunou; Myriam Cramet; Dorine Rossetto; Maria J Aristizabal; Nicolas Lacoste; Simon Drouin; Valérie Côté; Eric Paquet; Rhea T Utley; Nevan Krogan; François Robert; Michael S Kobor; Jacques Côté
Journal:  Mol Cell Biol       Date:  2016-10-28       Impact factor: 4.272
  1 in total

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