Literature DB >> 24950206

Of worms and men: HLH-30 and TFEB regulate tolerance to infection.

George R Tiller1, Danielle A Garsin2.   

Abstract

In this issue of Immunity, Visvikis et al. (2014) use the model host Caenorhabditis elegans to discover a role in innate immunity for the basic helix-loop-helix transcription factor, HLH-30. The finding inspires study of the mammalian ortholog TFEB, in which a similar role in immune response is ascertained.
Copyright © 2014 Elsevier Inc. All rights reserved.

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Year:  2014        PMID: 24950206      PMCID: PMC4126603          DOI: 10.1016/j.immuni.2014.06.002

Source DB:  PubMed          Journal:  Immunity        ISSN: 1074-7613            Impact factor:   31.745


  10 in total

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  6 in total

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