PURPOSE: The aim of this prospective observational cohort study was to evaluate long-term outcomes in patients with mild-to-moderate lumbar spinal stenosis (LSS) and to analyse the predictors of clinical outcomes. METHODS: A group of 53 patients were re-examined after a median period of 139 months. Evaluations were made of subjective clinical outcome, objective clinical outcome and its predictors, any correlation between subjective and objective outcome, and the development of changes in radiological and electrophysiological parameters after 12 years. RESULTS: Satisfactory objective and subjective clinical outcomes were recorded in 54.7 and 43.4% of patients, respectively. No statistically significant correlation between objective and subjective clinical outcome was found (Spearman coefficient = 0.225, p = 0.132). Patients with isolated unsatisfactory subjective outcome exhibited the highest Functional Comorbidity Index of all subgroups. Electrophysiological and radiological findings did not demonstrate statistically significant changes after 12-year follow-up. Multivariate logistic regression confirmed only the lowest transverse diameter of spinal canal ≦13.6 mm as an independent predictor of unsatisfactory clinical outcome (OR = 5.51). CONCLUSIONS: Satisfactory objective and subjective clinical outcomes were disclosed in about half of the patients with mild-to-moderate LSS in a 12-year follow-up. The number of comorbid diseases had an unfavourable effect on subjective evaluation of clinical outcome. The lowest transverse diameter of spinal canal proved to be the only independent predictor of deterioration of clinical status in LSS patients.
PURPOSE: The aim of this prospective observational cohort study was to evaluate long-term outcomes in patients with mild-to-moderate lumbar spinal stenosis (LSS) and to analyse the predictors of clinical outcomes. METHODS: A group of 53 patients were re-examined after a median period of 139 months. Evaluations were made of subjective clinical outcome, objective clinical outcome and its predictors, any correlation between subjective and objective outcome, and the development of changes in radiological and electrophysiological parameters after 12 years. RESULTS: Satisfactory objective and subjective clinical outcomes were recorded in 54.7 and 43.4% of patients, respectively. No statistically significant correlation between objective and subjective clinical outcome was found (Spearman coefficient = 0.225, p = 0.132). Patients with isolated unsatisfactory subjective outcome exhibited the highest Functional Comorbidity Index of all subgroups. Electrophysiological and radiological findings did not demonstrate statistically significant changes after 12-year follow-up. Multivariate logistic regression confirmed only the lowest transverse diameter of spinal canal ≦13.6 mm as an independent predictor of unsatisfactory clinical outcome (OR = 5.51). CONCLUSIONS: Satisfactory objective and subjective clinical outcomes were disclosed in about half of the patients with mild-to-moderate LSS in a 12-year follow-up. The number of comorbid diseases had an unfavourable effect on subjective evaluation of clinical outcome. The lowest transverse diameter of spinal canal proved to be the only independent predictor of deterioration of clinical status in LSS patients.
Authors: Steven J Atlas; Robert B Keller; Yen A Wu; Richard A Deyo; Daniel E Singer Journal: Spine (Phila Pa 1976) Date: 2005-04-15 Impact factor: 3.468
Authors: S J Atlas; R A Deyo; R B Keller; A M Chapin; D L Patrick; J M Long; D E Singer Journal: Spine (Phila Pa 1976) Date: 1996-08-01 Impact factor: 3.468
Authors: Eberhard Siebert; Harald Prüss; Randolf Klingebiel; Vieri Failli; Karl M Einhäupl; Jan M Schwab Journal: Nat Rev Neurol Date: 2009-07 Impact factor: 42.937
Authors: J N Katz; S J Lipson; G W Brick; L J Grobler; J N Weinstein; A H Fossel; R A Lew; M H Liang Journal: Spine (Phila Pa 1976) Date: 1995-05-15 Impact factor: 3.468
Authors: Ulrike Held; Jakob M Burgstaller; Maria M Wertli; Giuseppe Pichierri; Sebastian Winklhofer; Florian Brunner; François Porchet; Mazda Farshad; Johann Steurer Journal: PLoS One Date: 2018-11-08 Impact factor: 3.240
Authors: Sean D Rundell; Ayumi Saito; Eric N Meier; Stephanie T Danyluk; Jeffrey G Jarvik; Kelley Seebeck; Janna L Friedly; Patrick J Heagerty; Sandra K Johnston; Monica Smersh; Maggie E Horn; Pradeep Suri; Amy M Cizik; Adam P Goode Journal: BMC Musculoskelet Disord Date: 2022-07-21 Impact factor: 2.562