OBJECTIVES: To compare radiation exposure and image quality in children undergoing torso helical acquisitioncomputed tomography (CT) using filtered back projection (FBP) or adaptive iterative dose reduction (AIDR) 3D reconstruction algorithms. A secondary purpose is to compare radiation exposure and image quality in children undergoing torso CT acquired with helical or wide-detector techniques reconstructed with AIDR 3D. METHODS: The study was approved by the institutional review board. Phase 1 included 200 helical torso CT studies: 100 using FBP and 100 using AIDR 3D. The size-specific dose estimate (SSDE) was calculated for each study. Region of interest (ROI) noise measurements were recorded in the thorax, abdomen, and pelvis for each study. Unpaired t tests compared SSDE and image noise for each group. Phase 2 included 100 wide-detector CT torso studies using AIDR 3D. Size-specific dose estimate and ROI noise measurements were calculated. Unpaired t tests compared helical and wide-detector SSDE and ROI. Additional t tests looked for age- and weight-specific differences in the helical and wide-detector groups. RESULTS: Phase 1: AIDR 3D showed significant reduction in SSDE (P = 0.0001) and significant improvement in image quality. Phase 2: no significant difference in SSDE was observed. Children younger than 6 years had a significant reduction in SSDE with wide-detector technique (P = 0.0445) with no loss in image quality. CONCLUSIONS: Adaptive iterative dose reduction 3D produces significant reduction in radiation dose without degradation to image quality compared with FBP. Significant dose reduction without loss of image quality can also be obtained in younger, smaller children using wide-detector technique.
RCT Entities:
OBJECTIVES: To compare radiation exposure and image quality in children undergoing torso helical acquisition computed tomography (CT) using filtered back projection (FBP) or adaptive iterative dose reduction (AIDR) 3D reconstruction algorithms. A secondary purpose is to compare radiation exposure and image quality in children undergoing torso CT acquired with helical or wide-detector techniques reconstructed with AIDR 3D. METHODS: The study was approved by the institutional review board. Phase 1 included 200 helical torso CT studies: 100 using FBP and 100 using AIDR 3D. The size-specific dose estimate (SSDE) was calculated for each study. Region of interest (ROI) noise measurements were recorded in the thorax, abdomen, and pelvis for each study. Unpaired t tests compared SSDE and image noise for each group. Phase 2 included 100 wide-detector CT torso studies using AIDR 3D. Size-specific dose estimate and ROI noise measurements were calculated. Unpaired t tests compared helical and wide-detector SSDE and ROI. Additional t tests looked for age- and weight-specific differences in the helical and wide-detector groups. RESULTS: Phase 1: AIDR 3D showed significant reduction in SSDE (P = 0.0001) and significant improvement in image quality. Phase 2: no significant difference in SSDE was observed. Children younger than 6 years had a significant reduction in SSDE with wide-detector technique (P = 0.0445) with no loss in image quality. CONCLUSIONS: Adaptive iterative dose reduction 3D produces significant reduction in radiation dose without degradation to image quality compared with FBP. Significant dose reduction without loss of image quality can also be obtained in younger, smaller children using wide-detector technique.