Literature DB >> 24940127

Lund-mackay staging system in cystic fibrosis: a prognostic factor for revision surgery?

John M Carter1, Bradley T Johnson2, Amit Patel1, Enrique Palacios3, Kimsey H Rodriguez4.   

Abstract

BACKGROUND: Cystic fibrosis (CF) is an autosomal recessive genetic disease that affects approximately 30,000 people in the United States. Mucus in CF patients can be exceptionally viscous, leading to progressive cycles of inflammation and infection. The most widely accepted staging system used to score sinus computed tomography (CT) scans is the Lund-Mackay Score (LMS).
METHODS: To determine if a significant correlation exists between LMS and the need for revision sinus surgery in a patient population with CF, we performed a retrospective review of 32 patients with CF who were referred to the Tulane Otolaryngology Clinic from 2005 to 2011 and received a CT scan of the paranasal sinuses. CT scans were graded in a blinded manner by the institution's neuroradiologist using the LMS system.
RESULTS: We found no statistically significant difference in the raw or scaled LMSs between patients receiving revision surgery (n=9) and patients receiving a single surgery (n=23).
CONCLUSIONS: CT scans are vital for preoperative planning, but they are not a useful tool for risk stratification. More specifically, application of the LMS is not relevant in identifying which CF patients with chronic rhinosinusitis will be at risk for revision surgeries.

Entities:  

Keywords:  Cystic fibrosis; paranasal sinuses; surgical procedures–operative; tomography–x-ray computed

Year:  2014        PMID: 24940127      PMCID: PMC4052584     

Source DB:  PubMed          Journal:  Ochsner J        ISSN: 1524-5012


  12 in total

1.  Genotype-phenotype correlations for the paranasal sinuses in cystic fibrosis.

Authors:  M B Jorissen; K De Boeck; H Cuppens
Journal:  Am J Respir Crit Care Med       Date:  1999-05       Impact factor: 21.405

2.  The Lund-Mackay staging system for chronic rhinosinusitis: how is it used and what does it predict?

Authors:  Claire Hopkins; John P Browne; Rob Slack; Valerie Lund; Peter Brown
Journal:  Otolaryngol Head Neck Surg       Date:  2007-10       Impact factor: 3.497

3.  Cystic fibrosis and endoscopic sinus surgery: Relationship between nasal polyposis and likelihood of revision endoscopic sinus surgery in patients with cystic fibrosis.

Authors:  Scott Rickert; Victoria E Banuchi; Joan D Germana; Michael G Stewart; Max M April
Journal:  Arch Otolaryngol Head Neck Surg       Date:  2010-10

4.  Endoscopic sinus surgery in the treatment of cystic fibrosis with nasal polyposis.

Authors:  J M Rowe-Jones; I S Mackay
Journal:  Laryngoscope       Date:  1996-12       Impact factor: 3.325

Review 5.  Staging for rhinosinusitis.

Authors:  V J Lund; D W Kennedy
Journal:  Otolaryngol Head Neck Surg       Date:  1997-09       Impact factor: 5.591

6.  The usefulness of computed tomography scans in cystic fibrosis patients with chronic sinusitis.

Authors:  Andrea Barber McMurphy; Craig Morriss; Dianna B Roberts; Ellen M Friedman
Journal:  Am J Rhinol       Date:  2007 Nov-Dec

7.  Risk factors for recurrent sinus surgery in cystic fibrosis: review of a decade of experience.

Authors:  Samuel S Becker; Alessandro de Alarcon; Steven R Bomeli; Joseph K Han; Charles W Gross
Journal:  Am J Rhinol       Date:  2007 Jul-Aug

8.  Incidental paranasal sinus imaging abnormalities and the normal Lund score in children.

Authors:  Micah Hill; Neil Bhattacharyya; Theodore R Hall; Robert Lufkin; Nina L Shapiro
Journal:  Otolaryngol Head Neck Surg       Date:  2004-02       Impact factor: 3.497

9.  Adult cystic fibrosis.

Authors:  Michael P Boyle
Journal:  JAMA       Date:  2007-10-17       Impact factor: 56.272

10.  CT characterization of inflammatory paranasal sinus disease in cystic fibrosis.

Authors:  Heidi B Eggesbø; S Søvik; S Dølvik; F Kolmannskog
Journal:  Acta Radiol       Date:  2002-01       Impact factor: 1.701

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  3 in total

Review 1.  Recent publications by ochsner authors.

Authors: 
Journal:  Ochsner J       Date:  2014

2.  Radiological score of computed tomography scans predicts revision surgery for chronic rhinosinusitis.

Authors:  Markus Lilja; Anni Koskinen; Anna Julkunen-Iivari; Antti Mäkitie; Jura Numminen; Markus Rautiainen; Jyri P Myller; Antti Markkola; Mikko Suvinen; Mika Mäkelä; Risto Renkonen; Juha Pekkanen; Sanna K Toppila-Salmi
Journal:  Acta Otorhinolaryngol Ital       Date:  2022-02       Impact factor: 2.618

Review 3.  Chronic rhinosinusitis in cystic fibrosis: a review of therapeutic options.

Authors:  Joanna Krajewska; Krzysztof Zub; Adam Słowikowski; Tomasz Zatoński
Journal:  Eur Arch Otorhinolaryngol       Date:  2021-07-22       Impact factor: 2.503

  3 in total

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