Literature DB >> 17903570

The Lund-Mackay staging system for chronic rhinosinusitis: how is it used and what does it predict?

Claire Hopkins1, John P Browne, Rob Slack, Valerie Lund, Peter Brown.   

Abstract

OBJECTIVES: The Lund-Mackay score is widely used in assessment of chronic rhinosinusitis. We aimed to describe its relationship to other measures of pre- and post-treatment health status. STUDY
DESIGN: Multicenter prospective study of 1840 patients undergoing surgery for chronic rhinosinusitis in the UK.
RESULTS: There was no absolute threshold for surgery, but patients with higher Lund-Mackay scores underwent more extensive surgery. There was no correlation between Lund-Mackay and SNOT-22 scores. The Lund-Mackay increased with increasing grade of polyposis. The Lund-Mackay score was associated with symptom reduction (coefficient = 0.24, P = 0.02) complication rates (odds ratio, 1.08, 95%CI 1.06 to 1.1), and revision rates (odds ratio, 1.03, 95% CI 1.001 to 1.06).
CONCLUSIONS: The Lund-Mackay score measures a different aspect of disease to "subjective" symptom scores. However, it correlates well with other markers of disease severity, the nature of surgery offered, and its outcome. SIGNIFICANCE: This demonstrates the strengths and limitations of a commonly used staging system.

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Year:  2007        PMID: 17903570     DOI: 10.1016/j.otohns.2007.02.004

Source DB:  PubMed          Journal:  Otolaryngol Head Neck Surg        ISSN: 0194-5998            Impact factor:   3.497


  108 in total

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2.  Dysregulation of E-cadherin in chronic rhinosinusitis with nasal polyps.

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6.  The significance of osteitis in rhinosinusitis.

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7.  Longitudinal evaluation of clustering of chronic sinonasal and related symptoms using exploratory factor analysis.

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8.  The relationship between endoscopic and radiologic findings and olfactory status of patients with chronic rhinosinusitis with nasal polyps before and after the endoscopic sinus surgery.

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Review 9.  Quality of surgical field during endoscopic sinus surgery: a systematic literature review of the effect of total intravenous compared to inhalational anesthesia.

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10.  Association of the tumor necrosis factor-alpha -308 G/A polymorphism with nasal polyposis.

Authors:  Hunkar Batikhan; Mustafa Kursat Gokcan; Esen Beder; Nejat Akar; Aysenur Ozturk; Muharrem Gerceker
Journal:  Eur Arch Otorhinolaryngol       Date:  2009-12-11       Impact factor: 2.503

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