Literature DB >> 24937169

Combined topical application of a regenerative agent with a bandage contact lens for the treatment of persistent epithelial defects.

George D Kymionis1, Dimitrios A Liakopoulos, Michael A Grentzelos, Vasilios F Diakonis, Nektarios E Klados, Konstantinos I Tsoulnaras, Miltiadis K Tsilimbaris, Ioannis G Pallikaris.   

Abstract

PURPOSE: The aim of this study was to report 3 cases of persistent epithelial defects (PEDs) successfully treated with the combined topical application of a regenerative agent (RGTA; Cacicol20, OTR3, Paris, France) with a bandage contact lens (BCL).
METHODS: This is a case series.
RESULTS: Three patients suffering from a PED for 4-8 weeks and unresponsive to conventional therapy were treated with the combined application of an RGTA (Cacicol20) and a silicone hydrogel BCL. The PED healed in all patients after 4-21 days, and no side effects were noted.
CONCLUSIONS: The combination of an RGTA (Cacicol20) with a BCL seems to be an effective treatment for PED.

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Year:  2014        PMID: 24937169     DOI: 10.1097/ICO.0000000000000169

Source DB:  PubMed          Journal:  Cornea        ISSN: 0277-3740            Impact factor:   2.651


  9 in total

1.  Treatment of patients with neurotrophic keratitis stages 2 and 3 with plasma rich in growth factors (PRGF-Endoret) eye-drops.

Authors:  Ronald Mauricio Sanchez-Avila; Jesus Merayo-Lloves; Ana Cristina Riestra; Luis Fernandez-Vega Cueto; Eduardo Anitua; Leire Begoña; Francisco Muruzabal; Gorka Orive
Journal:  Int Ophthalmol       Date:  2017-06-15       Impact factor: 2.031

2.  Corneal matrix repair therapy with the regenerating agent in neurotrophic persistent epithelial defects.

Authors:  Canan Asli Utine; Ceren Engin Durmaz; Nilufer Koçak
Journal:  Int J Ophthalmol       Date:  2017-12-18       Impact factor: 1.779

3.  Noncontact Intraocular Pressure Measurement over Bandage Contact Lens and the Effect of Pentacam and Corvis ST's IOP Correction System.

Authors:  Xueting Cai; Yi Qin; Sixiu Liu; Zhewei Cheng; Fan Lu; Jia Qu; Ding Chen
Journal:  J Ophthalmol       Date:  2022-05-09       Impact factor: 1.974

4.  A pharmacological modification of pain and epithelial healing in contemporary transepithelial all-surface laser ablation (ASLA).

Authors:  Ioannis M Aslanides; Vasilis D Selimis; Nikolaos V Bessis; Panagiotis N Georgoudis
Journal:  Clin Ophthalmol       Date:  2015-04-15

5.  Treatment of Acanthamoeba neurotrophic corneal ulcer with topical matrix therapy.

Authors:  Antonio Mateo; Beatriz Abadía; Pilar Calvo; Enrique Minguez; Luis Pablo; José Manuel Benitez Del Castillo
Journal:  J Ophthalmic Inflamm Infect       Date:  2015-06-21

6.  Ocular surface chemical injury treated by regenerating agent (RGTA, Cacicol20).

Authors:  Melih Ustaoglu; Nilgun Solmaz; Feyza Onder
Journal:  GMS Ophthalmol Cases       Date:  2017-10-25

Review 7.  RGTA® or ReGeneraTing Agents mimic heparan sulfate in regenerative medicine: from concept to curing patients.

Authors:  Denis Barritault; Marie Gilbert-Sirieix; Kim Lee Rice; Fernando Siñeriz; Dulce Papy-Garcia; Christophe Baudouin; Pascal Desgranges; Gilbert Zakine; Jean-Louis Saffar; Johan van Neck
Journal:  Glycoconj J       Date:  2016-12-07       Impact factor: 2.916

8.  Evaluation of a new matrix regenerating agent in patients with Sjögren syndrome and superficial ulcerative keratitis resistant to conventional therapy: A report of 3 cases.

Authors:  Franck Fajnkuchen; Denis Barritault; Audrey Giocanti-Aurégan
Journal:  Medicine (Baltimore)       Date:  2018-03       Impact factor: 1.889

Review 9.  Persistent Corneal Epithelial Defects: A Review Article.

Authors:  Uma Vaidyanathan; Grant C Hopping; Harry Y Liu; Anisha N Somani; Yasmyne C Ronquillo; Phillip C Hoopes; Majid Moshirfar
Journal:  Med Hypothesis Discov Innov Ophthalmol       Date:  2019
  9 in total

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