BACKGROUND: Mycosis fungoides (MF), the most common subtype of cutaneous T-Cell Lymphoma (CTCL), is a rare chronic skin neoplasia. Total skin electron irradiation has been employed along with a variety of other topical or systemic treatments for MF management. AIM: To report the first case treated by TSEB irradiation protocol in Greece. MATERIALS AND METHODS: A fractionated 36 Gy total skin electron beam (TSEB) therapy was prescribed to a 65-years-old male patient with mycosis fungoides (MF), stage IIB, refractory to several treatments during a 20-year period. Dose uniform delivery was monitored by thermo-luminescence dosimetry. RESULTS AND DISCUSSION: The homogeneous skin dose distribution resulted in a complete clinical response. Limited, irradiation-oriented, side effects appeared. CONCLUSIONS: The first TSEB irradiation prescription in Greek medical chronicles was proved effective in this case of tumor stage MF (T3-IIB), which had been refractory to several single or combination treatments.
BACKGROUND:Mycosis fungoides (MF), the most common subtype of cutaneous T-Cell Lymphoma (CTCL), is a rare chronic skin neoplasia. Total skin electron irradiation has been employed along with a variety of other topical or systemic treatments for MF management. AIM: To report the first case treated by TSEB irradiation protocol in Greece. MATERIALS AND METHODS: A fractionated 36 Gy total skin electron beam (TSEB) therapy was prescribed to a 65-years-old male patient with mycosis fungoides (MF), stage IIB, refractory to several treatments during a 20-year period. Dose uniform delivery was monitored by thermo-luminescence dosimetry. RESULTS AND DISCUSSION: The homogeneous skin dose distribution resulted in a complete clinical response. Limited, irradiation-oriented, side effects appeared. CONCLUSIONS: The first TSEB irradiation prescription in Greek medical chronicles was proved effective in this case of tumor stage MF (T3-IIB), which had been refractory to several single or combination treatments.
Authors: S Diamantopoulos; K Platoni; M Dilvoi; I Nazos; K Geropantas; G Maravelis; M Tolia; I Beli; E Efstathopoulos; P Pantelakos; G Panayiotakis; V Kouloulias Journal: Phys Med Date: 2010-10-14 Impact factor: 2.685
Authors: K Platoni; S Diamantopoulos; G Panayiotakis; V Kouloulias; P Pantelakos; N Kelekis; E Efstathopoulos Journal: Phys Med Date: 2011-04-22 Impact factor: 2.685
Authors: M R Kamstrup; L M Lindahl; R Gniadecki; L Iversen; L Skov; P M Petersen; A Loft; L Specht Journal: Br J Dermatol Date: 2012-01-09 Impact factor: 9.302