Sheng-Hsiang Lin1, Yu-Shu Liao2, Shih-Horng Huang3, Wan-Hsiu Liao4. 1. Department of Internal Medicine, New Taipei City Hospital, No. 3, Section 1, New Taipei Boulevard, San-Chong District, New Taipei 24141, Taiwan; Department of Respiratory Therapy, Fu-Jen Catholic University, No. 510, Zhong-Zheng Road, Xin-Zhuang District, New Taipei 24205, Taiwan. 2. Department of Prosthodontic, Chang-Gung Memorial Hospital, No. 199, Tung-Hwa North Road, Song-Shan District, Taipei 10507, Taiwan. 3. Department of Surgery, New Taipei City Hospital, No. 3, Section 1, New Taipei Boulevard, San-Chong District, New Taipei 24141, Taiwan. 4. Department of Family Medicine, New Taipei City Hospital, No. 3, Section 1, New Taipei Boulevard, San-Chong District, New Taipei 24141, Taiwan; Department of Family Medicine, National Taiwan University Hospital, No. 7, Chung-Shan South Road, Zhong-Zheng District, Taipei 10002, Taiwan. Electronic address: liaowh1976@gmail.com.
Abstract
BACKGROUND: The association between betel quid (BQ) chewing and oral cancer is well established. However, evidence regarding the relationship between BQ chewing and cardiovascular disease (CVD) is still insufficient. METHODS: This cross-sectional study included 2002 men and 1175 women aged 50 and older in a city-level health examination survey of an agricultural and fishing population in 2013. In addition to anthropometric parameters, CVD risks were estimated using high-sensitivity C-reactive protein (hs-CRP), brachial-ankle pulse wave velocity (baPWV) and ankle-brachial index. Age, gender, smoking and alcohol drinking status were all incorporated into the multivariate logistic regression model to delineate the effect of BQ chewing on CVD risks. RESULTS: Two hundred forty-one (12%) males and eight (0.7%) females were ever chewers. BQ chewing was an independent risk factor for general obesity (odds ratio [OR] 1.43, 95% confidence interval [CI] 1.07-1.91, p=0.017), central obesity (OR 2.27, 95% CI 1.53-3.37, p<0.001) and an elevated hs-CRP level (OR 1.38, 95% CI 1.03-1.85, p=0.029). Subjects who chewed more frequently had a higher systolic blood pressure (p=0.025) and baPWV (p=0.006). The waist circumference (p=0.015) and waist-to-height ratio (p=0.022) were greater in current chewers than in former chewers. CONCLUSION: These findings suggest that BQ chewing is associated with obesity and a higher CVD risk as estimated by hs-CRP. Furthermore, potential beneficial effects of BQ chewing cessation on central obesity were also found.
BACKGROUND: The association between betel quid (BQ) chewing and oral cancer is well established. However, evidence regarding the relationship between BQ chewing and cardiovascular disease (CVD) is still insufficient. METHODS: This cross-sectional study included 2002 men and 1175 women aged 50 and older in a city-level health examination survey of an agricultural and fishing population in 2013. In addition to anthropometric parameters, CVD risks were estimated using high-sensitivity C-reactive protein (hs-CRP), brachial-ankle pulse wave velocity (baPWV) and ankle-brachial index. Age, gender, smoking and alcohol drinking status were all incorporated into the multivariate logistic regression model to delineate the effect of BQ chewing on CVD risks. RESULTS: Two hundred forty-one (12%) males and eight (0.7%) females were ever chewers. BQ chewing was an independent risk factor for general obesity (odds ratio [OR] 1.43, 95% confidence interval [CI] 1.07-1.91, p=0.017), central obesity (OR 2.27, 95% CI 1.53-3.37, p<0.001) and an elevated hs-CRP level (OR 1.38, 95% CI 1.03-1.85, p=0.029). Subjects who chewed more frequently had a higher systolic blood pressure (p=0.025) and baPWV (p=0.006). The waist circumference (p=0.015) and waist-to-height ratio (p=0.022) were greater in current chewers than in former chewers. CONCLUSION: These findings suggest that BQ chewing is associated with obesity and a higher CVD risk as estimated by hs-CRP. Furthermore, potential beneficial effects of BQ chewing cessation on central obesity were also found.
Authors: Tsai-Tung Chiu; Tien-Lung Tsai; Mei-Yin Su; Tsan Yang; Peng-Lin Tseng; Yau-Jiunn Lee; Chao-Hsien Lee Journal: Int J Environ Res Public Health Date: 2021-01-04 Impact factor: 3.390
Authors: Suzanne M de la Monte; Natalia Moriel; Amy Lin; Nada Abdullah Tanoukhy; Camille Homans; Gina Gallucci; Ming Tong; Ayumi Saito Journal: Int J Environ Res Public Health Date: 2020-09-14 Impact factor: 3.390