Literature DB >> 24929155

Implementation of a high-dose-rate brachytherapy program for carcinoma of the cervix in Senegal: a pragmatic model for the developing world.

John P Einck1, Alana Hudson2, Adam C Shulman3, Catheryn M Yashar4, Mamadou M Dieng5, Magatte Diagne5, Latifatou Gueye5, Fama Gningue5, Pape M Gaye5, Brandon J Fisher6, Arno J Mundt4, Derek W Brown2.   

Abstract

West Africa has one of the highest incidence rates of carcinoma of the cervix in the world. The vast majority of women do not have access to screening or disease treatment, leading to presentation at advanced stages and to high mortality rates. Compounding this problem is the lack of radiation treatment facilities in Senegal and many other parts of the African continent. Senegal, a country of 13 million people, had a single (60)Co teletherapy unit before our involvement and no brachytherapy capabilities. Radiating Hope, a nonprofit organization whose mission is to provide radiation therapy equipment to countries in the developing world, provided a high-dose-rate afterloading unit to the cancer center for curative cervical cancer treatment. Here we describe the implementation of high-dose-rate brachytherapy in Senegal requiring a nonstandard fractionation schedule and a novel treatment planning approach as a possible blueprint to providing this technology to other developing countries.
Copyright © 2014 Elsevier Inc. All rights reserved.

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Year:  2014        PMID: 24929155     DOI: 10.1016/j.ijrobp.2013.12.008

Source DB:  PubMed          Journal:  Int J Radiat Oncol Biol Phys        ISSN: 0360-3016            Impact factor:   7.038


  18 in total

Review 1.  Brachytherapy in Gynecologic Cancers: Why Is It Underused?

Authors:  Kathy Han; Akila N Viswanathan
Journal:  Curr Oncol Rep       Date:  2016-04       Impact factor: 5.075

2.  Barriers and facilitators to implementation of cancer treatment and palliative care strategies in low- and middle-income countries: systematic review.

Authors:  Andrew Donkor; Tim Luckett; Sanchia Aranda; Jane Phillips
Journal:  Int J Public Health       Date:  2018-07-05       Impact factor: 3.380

3.  A Comparative Analysis of Two Different Dose Fractionation Regimens of High Dose Rate Intracavitary Brachytherapy in Treatment of Carcinoma of Uterine Cervix: A Prospective Randomized Study.

Authors:  Bonala Sreenivasa Rao; Pranabandhu Das; Bala Venkata Subramanian; Amitabh Jena; Patnayak Rashmi; V L Anusha Konakalla; Kuna Jayasree
Journal:  J Clin Diagn Res       Date:  2017-04-01

Review 4.  Establishing and Delivering Quality Radiation Therapy in Resource-Constrained Settings: The Story of Botswana.

Authors:  Jason A Efstathiou; Magda Heunis; Talkmore Karumekayi; Remigio Makufa; Memory Bvochora-Nsingo; David P Gierga; Gita Suneja; Surbhi Grover; Joseph Kasese; Mompati Mmalane; Howard Moffat; Alexander von Paleske; Joseph Makhema; Scott Dryden-Peterson
Journal:  J Clin Oncol       Date:  2015-11-17       Impact factor: 44.544

5.  Alantolactone induces apoptosis of human cervical cancer cells via reactive oxygen species generation, glutathione depletion and inhibition of the Bcl-2/Bax signaling pathway.

Authors:  Yan Jiang; Hanjie Xu; Jiafei Wang
Journal:  Oncol Lett       Date:  2016-04-28       Impact factor: 2.967

6.  Editorial: "global challenges in radiation oncology".

Authors:  Daniel Grant Petereit; C Norman Coleman
Journal:  Front Oncol       Date:  2015-05-15       Impact factor: 6.244

7.  A systematic review of radiotherapy capacity in low- and middle-income countries.

Authors:  Surbhi Grover; Melody J Xu; Alyssa Yeager; Lori Rosman; Reinou S Groen; Smita Chackungal; Danielle Rodin; Margaret Mangaali; Sommer Nurkic; Annemarie Fernandes; Lilie L Lin; Gillian Thomas; Ana I Tergas
Journal:  Front Oncol       Date:  2015-01-22       Impact factor: 6.244

Review 8.  The international cancer expert corps: a unique approach for sustainable cancer care in low and lower-middle income countries.

Authors:  C Norman Coleman; Silvia C Formenti; Tim R Williams; Daniel G Petereit; Khee C Soo; John Wong; Nelson Chao; Lawrence N Shulman; Surbhi Grover; Ian Magrath; Stephen Hahn; Fei-Fei Liu; Theodore DeWeese; Samir N Khleif; Michael Steinberg; Lawrence Roth; David A Pistenmaa; Richard R Love; Majid Mohiuddin; Bhadrasain Vikram
Journal:  Front Oncol       Date:  2014-11-19       Impact factor: 6.244

Review 9.  Radiation therapy and cancer control in developing countries: Can we save more lives?

Authors:  Rajamanickam Baskar; Koji Itahana
Journal:  Int J Med Sci       Date:  2017-01-01       Impact factor: 3.738

Review 10.  Cervical cancer prevention and treatment research in Africa: a systematic review from a public health perspective.

Authors:  Sarah Finocchario-Kessler; Catherine Wexler; May Maloba; Natabhona Mabachi; Florence Ndikum-Moffor; Elizabeth Bukusi
Journal:  BMC Womens Health       Date:  2016-06-04       Impact factor: 2.809

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