Literature DB >> 24926011

Virology. Response to Comment on "Specific and nonhepatotoxic degradation of nuclear hepatitis B virus cccDNA".

Yuchen Xia1, Julie Lucifora1, Florian Reisinger1, Mathias Heikenwalder1, Ulrike Protzer2.   

Abstract

Chisari et al. challenge our central conclusion that the hepatitis B virus (HBV) persistent form, the covalently closed circular DNA (cccDNA), is degraded in a noncytotoxic and specific fashion in the nucleus of infected hepatocytes. Specificity of the assays used, exclusion of cell division or death, and activity of APOBEC3 deaminases in the nucleus, however, were addressed in the paper.
Copyright © 2014, American Association for the Advancement of Science.

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Year:  2014        PMID: 24926011     DOI: 10.1126/science.1254083

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  13 in total

1.  T5 Exonuclease Hydrolysis of Hepatitis B Virus Replicative Intermediates Allows Reliable Quantification and Fast Drug Efficacy Testing of Covalently Closed Circular DNA by PCR.

Authors:  Bingqian Qu; Yi Ni; Florian A Lempp; Florian W R Vondran; Stephan Urban
Journal:  J Virol       Date:  2018-11-12       Impact factor: 5.103

Review 2.  The Woodchuck, a Nonprimate Model for Immunopathogenesis and Therapeutic Immunomodulation in Chronic Hepatitis B Virus Infection.

Authors:  Michael Roggendorf; Anna D Kosinska; Jia Liu; Mengji Lu
Journal:  Cold Spring Harb Perspect Med       Date:  2015-10-28       Impact factor: 6.915

3.  A global scientific strategy to cure hepatitis B.

Authors:  Peter A Revill; Francis V Chisari; Joan M Block; Maura Dandri; Adam J Gehring; Haitao Guo; Jianming Hu; Anna Kramvis; Pietro Lampertico; Harry L A Janssen; Massimo Levrero; Wenhui Li; T Jake Liang; Seng-Gee Lim; Fengmin Lu; M Capucine Penicaud; John E Tavis; Robert Thimme; Fabien Zoulim
Journal:  Lancet Gastroenterol Hepatol       Date:  2019-04-10

Review 4.  Search for a cure for chronic hepatitis B infection: How close are we?

Authors:  Wah Wah Phyo; Alex Yu Sen Soh; Seng Gee Lim; Guan Huei Lee
Journal:  World J Hepatol       Date:  2015-05-28

Review 5.  Targeting the multifunctional HBV core protein as a potential cure for chronic hepatitis B.

Authors:  Usha Viswanathan; Nagraj Mani; Zhanying Hu; Haiqun Ban; Yanming Du; Jin Hu; Jinhong Chang; Ju-Tao Guo
Journal:  Antiviral Res       Date:  2020-08-17       Impact factor: 5.970

6.  APOBEC3B lysine residues are dispensable for DNA cytosine deamination, HIV-1 restriction, and nuclear localization.

Authors:  Amy M Molan; Heather M Hanson; Cynthia M Chweya; Brett D Anderson; Gabriel J Starrett; Christopher M Richards; Reuben S Harris
Journal:  Virology       Date:  2017-08-23       Impact factor: 3.616

7.  Development of magnetic capture hybridization and quantitative polymerase chain reaction for hepatitis B virus covalently closed circular DNA.

Authors:  Yongcan Guo; Shangchun Sheng; Bin Nie; Zhiguang Tu
Journal:  Hepat Mon       Date:  2015-01-05       Impact factor: 0.660

Review 8.  Therapeutic vaccination and immunomodulation in the treatment of chronic hepatitis B: preclinical studies in the woodchuck.

Authors:  Anna D Kosinska; Jia Liu; Mengji Lu; Michael Roggendorf
Journal:  Med Microbiol Immunol       Date:  2014-12-23       Impact factor: 3.402

Review 9.  A Role for the Host DNA Damage Response in Hepatitis B Virus cccDNA Formation-and Beyond?

Authors:  Sabrina Schreiner; Michael Nassal
Journal:  Viruses       Date:  2017-05-22       Impact factor: 5.048

10.  Secreted Interferon-Inducible Factors Restrict Hepatitis B and C Virus Entry In Vitro.

Authors:  Yuchen Xia; Xiaoming Cheng; Christoph K Blossey; Karin Wisskirchen; Knud Esser; Ulrike Protzer
Journal:  J Immunol Res       Date:  2017-03-06       Impact factor: 4.818

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