Literature DB >> 24917733

Hematuria secondary to benign prostatic hyperplasia: retrospective analysis of 166 men identified in a single one stop hematuria clinic.

Nikhil Vasdev1, Ashish Kumar1, Rajan Veeratterapillay1, Andrew C Thorpe1.   

Abstract

INTRODUCTION: Hematuria secondary to benign prostatic hyperplasia (BPH) can occur due to a vascular primary gland itself or due to the vascular re-growth of the prostate following a transurethral resection of the prostate (TURP). We aim to evaluate the clinical presentation and management in patients within both these groups.
MATERIALS AND METHODS: We retrospectively archived the data of 166 men diagnosed with hematuria secondary to BPH from our hematuria clinic database from March 2003 and March 2006. The 166 patients were divided into 2 groups: Group I (n = 94) hematuria with no previous TURP; Group II (n = 72) hematuria with previous TURP. The clinical management in both groups included reassurance, commencement of a 5-alpha reductase inhibitor (finasteride) or a primary TURP in Group I or re-do TURP in Group II.
RESULTS: The median age was 73 years (range 45-94 years) for both groups. Outcomes combined for both groups included: reassurance alone in 26% (n = 43), finasteride in 51% (n = 84) and TURP in 12% (n = 19). Patients managed with reassurance alone or TURP had no further episodes of hematuria. At a mean follow-up was 18 months (range 7-22 months), 2 patients treated with finasteride re-bled but did require further intervention. A further 2 men elected to stop finasteride due to erectile dysfunction and gynecomastia respectively.
CONCLUSION: BPH can present with hematuria. Following re-evaluation in a hematuria clinic, the lack of any subsequent cancer diagnosis in these patients suggests that repeat hematuria investigations should be carefully re-considered.

Entities:  

Keywords:  Benign prostatic hyperplasia; Hematuria

Year:  2012        PMID: 24917733      PMCID: PMC3783295          DOI: 10.1159/000343529

Source DB:  PubMed          Journal:  Curr Urol        ISSN: 1661-7649


  7 in total

1.  A prospective analysis of the diagnostic yield resulting from the attendance of 4020 patients at a protocol-driven haematuria clinic.

Authors:  Tom J Edwards; Andrew J Dickinson; Salvatore Natale; Jane Gosling; John S McGrath
Journal:  BJU Int       Date:  2006-02       Impact factor: 5.588

2.  Strategies for asymptomatic microscopic hematuria: a prospective study of 1,034 patients.

Authors:  S Murakami; T Igarashi; S Hara; J Shimazaki
Journal:  J Urol       Date:  1990-07       Impact factor: 7.450

3.  A prospective analysis of 1,930 patients with hematuria to evaluate current diagnostic practice.

Authors:  M H Khadra; R S Pickard; M Charlton; P H Powell; D E Neal
Journal:  J Urol       Date:  2000-02       Impact factor: 7.450

4.  Asymptomatic microscopic hematuria.

Authors:  A L Golin; R S Howard
Journal:  J Urol       Date:  1980-09       Impact factor: 7.450

5.  Hematuria and the use of nonsteroidal anti-inflammatory drugs.

Authors:  S E Kraus; M B Siroky; R K Babayan; R J Krane
Journal:  J Urol       Date:  1984-08       Impact factor: 7.450

6.  Use of a bleeding time determination in the evaluation of unexplained hematuria.

Authors:  O Benton; J Lazarchick; J K Orak; W R Turner
Journal:  J Urol       Date:  1987-03       Impact factor: 7.450

7.  The significance of adult hematuria: 1,000 hematuria evaluations including a risk-benefit and cost-effectiveness analysis.

Authors:  A J Mariani; M C Mariani; C Macchioni; U K Stams; A Hariharan; A Moriera
Journal:  J Urol       Date:  1989-02       Impact factor: 7.450

  7 in total
  2 in total

1.  [Differential diagnosis of hematuria].

Authors:  M Horstmann; T Franiel; M O Grimm
Journal:  Urologe A       Date:  2014-08       Impact factor: 0.639

2.  Association Between Use of Antithrombotic Medication and Hematuria-Related Complications.

Authors:  Christopher J D Wallis; Tristan Juvet; Yuna Lee; Rano Matta; Sender Herschorn; Ronald Kodama; Girish S Kulkarni; Raj Satkunasivam; William Geerts; Anne McLeod; Steven A Narod; Robert K Nam
Journal:  JAMA       Date:  2017-10-03       Impact factor: 56.272

  2 in total

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