| Literature DB >> 24914247 |
Jesse R McAtee1, Sara E S Martin1, Andrew P Cinderella1, William B Reid1, Keywan A Johnson1, Donald A Watson1.
Abstract
For the first time, nickel-catalyzed silyl-Heck reactions are reported. Using simple phosphine-supported nickel catalysts, direct activation of silyl triflates has been achieved. These results contrast earlier palladium-catalyzed systems, which require iodide additives to activate silyl-triflates. These nickel-based catalysts exhibit good functional group tolerance in the preparation of vinyl silanes, and unlike earlier systems, allows for the incorporation of trialkylsilanes larger than Me3Si.Entities:
Year: 2014 PMID： 24914247 PMCID： PMC4047519 DOI： 10.1016/j.tet.2014.03.021
Source DB: PubMed Journal: Tetrahedron ISSN： 0040-4020 Impact factor: 2.457