Literature DB >> 24907464

Small molecule delivery through nanofibrous scaffolds for musculoskeletal regenerative engineering.

Erica J Carbone1, Tao Jiang1, Clarke Nelson2, Nicole Henry3, Kevin W-H Lo4.   

Abstract

Musculoskeletal regenerative engineering approach using small bioactive molecules in conjunction with advanced materials has emerged as a highly promising strategy for musculoskeletal repair and regeneration. Advanced biomaterials technologies have revealed nanofiber-based scaffolds for musculoskeletal tissue engineering as vehicles for the controlled delivery of small molecule drugs. This review article highlights recent advances in nanofiber-based delivery of small molecules for musculoskeletal regenerative engineering. The article concludes with perspectives on the challenges and future directions. FROM THE CLINICAL EDITOR: In this review, advances in nanofiber-based delivery of small molecules are discussed from the standpoint of their potential role in musculoskeletal regenerative engineering, highlighting both future directions and current challenges.
Copyright © 2014 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Drug delivery; Musculoskeletal disorders; Nanofibers; Small molecules; Tissue engineering

Mesh：

Substances：

Year:  2014        PMID： 24907464      PMCID： PMC4497775          DOI： 10.1016/j.nano.2014.05.013

Source DB:  PubMed          Journal:  Nanomedicine        ISSN： 1549-9634            Impact factor:   5.307


  87 in total

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Authors:  P C Bessa; M Casal; R L Reis
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Review 2.  Small-molecule based musculoskeletal regenerative engineering.

Authors:  Kevin W-H Lo; Tao Jiang; Keith A Gagnon; Clarke Nelson; Cato T Laurencin
Journal:  Trends Biotechnol       Date:  2014-01-06       Impact factor: 19.536

3.  Peptide functionalized polyhydroxyalkanoate nanofibrous scaffolds enhance Schwann cells activity.

Authors:  Elahe Masaeli; Paul A Wieringa; Mohammad Morshed; Mohammad H Nasr-Esfahani; Saeid Sadri; Clemens A van Blitterswijk; Lorenzo Moroni
Journal:  Nanomedicine       Date:  2014-05-02       Impact factor: 5.307

4.  Stimulation of bone formation in vitro and in rodents by statins.

Authors:  G Mundy; R Garrett; S Harris; J Chan; D Chen; G Rossini; B Boyce; M Zhao; G Gutierrez
Journal:  Science       Date:  1999-12-03       Impact factor: 47.728

5.  Plasma surface modification of poly(D,L-lactic acid) as a tool to enhance protein adsorption and the attachment of different cell types.

Authors:  C M Alves; Y Yang; D Marton; D L Carnes; J L Ong; V L Sylvia; D D Dean; R L Reis; C M Agrawal
Journal:  J Biomed Mater Res B Appl Biomater       Date:  2008-10       Impact factor: 3.368

6.  cAMP/PKA pathway activation in human mesenchymal stem cells in vitro results in robust bone formation in vivo.

Authors:  Ramakrishnaiah Siddappa; Anton Martens; Joyce Doorn; Anouk Leusink; Cristina Olivo; Ruud Licht; Linda van Rijn; Claudia Gaspar; Riccardo Fodde; Frank Janssen; Clemens van Blitterswijk; Jan de Boer
Journal:  Proc Natl Acad Sci U S A       Date:  2008-05-19       Impact factor: 11.205

Review 7.  Current advances in research and clinical applications of PLGA-based nanotechnology.

Authors:  Jian-Ming Lü; Xinwen Wang; Christian Marin-Muller; Hao Wang; Peter H Lin; Qizhi Yao; Changyi Chen
Journal:  Expert Rev Mol Diagn       Date:  2009-05       Impact factor: 5.225

8.  One-day treatment of small molecule 8-bromo-cyclic AMP analogue induces cell-based VEGF production for in vitro angiogenesis and osteoblastic differentiation.

Authors:  Kevin W-H Lo; Ho Man Kan; Keith A Gagnon; Cato T Laurencin
Journal:  J Tissue Eng Regen Med       Date:  2013-11-06       Impact factor: 3.963

9.  A short review: Recent advances in electrospinning for bone tissue regeneration.

Authors:  Song-Hee Shin; Odnoo Purevdorj; Oscar Castano; Josep A Planell; Hae-Won Kim
Journal:  J Tissue Eng       Date:  2012-04-04       Impact factor: 7.813

Review 10.  Bone regenerative medicine: classic options, novel strategies, and future directions.

Authors:  Ahmad Oryan; Soodeh Alidadi; Ali Moshiri; Nicola Maffulli
Journal:  J Orthop Surg Res       Date:  2014-03-17       Impact factor: 2.359
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  7 in total

Review 1.  MiRNA inhibition in tissue engineering and regenerative medicine.

Authors:  Kelsey R Beavers; Christopher E Nelson; Craig L Duvall
Journal:  Adv Drug Deliv Rev       Date:  2014-12-29       Impact factor: 15.470

2.  Glycogen synthase kinase-3β inhibitor promotes the migration and osteogenic differentiation of rat dental pulp stem cells via the β-catenin/PI3K/Akt signaling pathway.

Authors:  Huilan Xie; Yi Lin; Fang Fang
Journal:  J Dent Sci       Date:  2021-10-16       Impact factor: 3.719

3.  Incorporation of simvastatin in PLLA membranes for guided bone regeneration: effect of thermal treatment on simvastatin release.

Authors:  Antonio G B Castro; Dennis W P M Löwik; Mies J van Steenbergen; John A Jansen; Jeroen J J P van den Beucken; Fang Yang
Journal:  RSC Adv       Date:  2018-08-10       Impact factor: 4.036

Review 4.  Nanotechnology Scaffolds for Alveolar Bone Regeneration.

Authors:  Goker Funda; Silvio Taschieri; Giannì Aldo Bruno; Emma Grecchi; Savadori Paolo; Donati Girolamo; Massimo Del Fabbro
Journal:  Materials (Basel)       Date:  2020-01-03       Impact factor: 3.623

5.  Fabrication of Silk Scaffold Containing Simvastatin-Loaded Silk Fibroin Nanoparticles for Regenerating Bone Defects

Authors:  Fatemeh Mottaghitalab; Hamidreza Motasadizadeh; Mohammad Ali Shokrgozar; Shahrokh Shojaei; Mehdi Farokhi
Journal:  Iran Biomed J       Date:  2022-03-01

6.  Osteogenesis Improvement of Gelatin-Based Nanocomposite Scaffold by Loading Zoledronic Acid.

Authors:  Sayed Behnam Abdulahy; Mona Esmaeili Bidhendi; Mohammad Reza Vaezi; Mehrdad Moosazadeh Moghaddam
Journal:  Front Bioeng Biotechnol       Date:  2022-04-25

Review 7.  Electrospun Biomimetic Nanofibrous Scaffolds: A Promising Prospect for Bone Tissue Engineering and Regenerative Medicine.

Authors:  Shabnam Anjum; Farheen Rahman; Prashant Pandey; Dilip Kumar Arya; Mahmood Alam; Paruvathanahalli Siddalingam Rajinikanth; Qiang Ao
Journal:  Int J Mol Sci       Date:  2022-08-16       Impact factor: 6.208
  7 in total

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