Literature DB >> 24907219

Management of a mixed overdose of calcium channel blockers, β-blockers and statins.

Reena Thakrar1, Rob Shulman2, Geoff Bellingan3, Mervyn Singer4.   

Abstract

We describe a case of extreme mixed overdose of calcium channel blockers, β-blockers and statins. The patient was successfully treated with aggressive resuscitation including cardiac pacing and multiorgan support, glucagon and high-dose insulin for toxicity related to calcium channel blockade and β-blockade, and ubiquinone for treating severe presumed statin-induced rhabdomyolysis and muscle weakness. 2014 BMJ Publishing Group Ltd.

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Year:  2014        PMID： 24907219      PMCID： PMC4054325          DOI： 10.1136/bcr-2014-204732

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN： 1757-790X


  39 in total

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Journal:  Trends Pharmacol Sci       Date:  1999-03       Impact factor: 14.819

2.  Effect of atorvastatin on left ventricular diastolic function and ability of coenzyme Q10 to reverse that dysfunction.

Authors:  Marc A Silver; Peter H Langsjoen; Szabolcs Szabo; Harish Patil; Allan Zelinger
Journal:  Am J Cardiol       Date:  2004-11-15       Impact factor: 2.778

3.  Insulin improves heart function and metabolism during non-ischemic cardiogenic shock in awake canines.

Authors:  J A Kline; R M Raymond; E D Leonova; T C Williams; J A Watts
Journal:  Cardiovasc Res       Date:  1997-05       Impact factor: 10.787

Review 4.  Regulation of the mevalonate pathway.

Authors:  J L Goldstein; M S Brown
Journal:  Nature       Date:  1990-02-01       Impact factor: 49.962

5.  [Case of severe rhabdomyolosis after protracted overdose of simvastatin].

Authors:  Tine Greve
Journal:  Ugeskr Laeger       Date:  2008-09-15

Review 6.  Statin-induced rhabdomyolysis.

Authors:  Donald H Schreiber; Thomas R Anderson
Journal:  J Emerg Med       Date:  2006-08       Impact factor: 1.484

7.  Phase II study of high-dose lovastatin in patients with advanced gastric adenocarcinoma.

Authors:  W S Kim; M M Kim; H J Choi; S S Yoon; M H Lee; K Park; C H Park; W K Kang
Journal:  Invest New Drugs       Date:  2001       Impact factor: 3.850

8.  Insulin infusion in conscious dogs. Effects on systemic and coronary hemodynamics, regional blood flows, and plasma catecholamines.

Authors:  C Liang; J U Doherty; R Faillace; K Maekawa; S Arnold; H Gavras; W B Hood
Journal:  J Clin Invest       Date:  1982-06       Impact factor: 14.808

Review 9.  Management of calcium channel antagonist overdose.

Authors:  Steven D Salhanick; Michael W Shannon
Journal:  Drug Saf       Date:  2003       Impact factor: 5.606

10.  Beneficial myocardial metabolic effects of insulin during verapamil toxicity in the anesthetized canine.

Authors:  J A Kline; E Leonova; R M Raymond
Journal:  Crit Care Med       Date:  1995-07       Impact factor: 7.598
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  1 in total

1.  Experts Consensus Recommendations for the Management of Calcium Channel Blocker Poisoning in Adults.

Authors:  Maude St-Onge; Kurt Anseeuw; Frank Lee Cantrell; Ian C Gilchrist; Philippe Hantson; Benoit Bailey; Valéry Lavergne; Sophie Gosselin; William Kerns; Martin Laliberté; Eric J Lavonas; David N Juurlink; John Muscedere; Chen-Chang Yang; Tasnim Sinuff; Michael Rieder; Bruno Mégarbane
Journal:  Crit Care Med       Date:  2017-03       Impact factor: 7.598
  1 in total

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