Literature DB >> 24902532

A controlled evaluation of a targeted early case detection intervention for reducing delay in treatment of first episode psychosis.

Ashok Malla1, Gerald Jordan, Ridha Joober, Norbert Schmitz, Ross Norman, Thomas Brown, Karen Goldberg, Heleen Loohuis, Nadia Vracotas, Joseph Rochford.   

Abstract

PURPOSE: Interventions aimed at influencing specific pathways to care may reduce the duration of untreated psychosis (DUP). The purpose of this study was to reduce delay in referral to an early intervention service following first contact for help seeking for psychosis in a defined urban catchment area.
METHODS: Using a historical control design, we conducted a targeted intervention comprised of intensive training and education regarding first onset of psychosis and benefits of early intervention with all potential points of contact in pathways to care in a defined catchment area of a specialized early intervention (EI) service. Data collected on different components of DUP [help seeking (H-DUP) and referral (R-DUP)] and demographic and clinical characteristics on patients seeking treatment of first episode of a psychotic (FEP) disorder accepted in the EI service for 3 years before and 3 years after the intervention were contrasted. No other systemic changes occurred in this catchment area during this period.
RESULTS: There was a significant increase in the number of cases of FEP referred to the EI service post-intervention from hospitals other than the parent institute, in the proportion with a diagnosis of affective psychosis and proportion of patients from a lower socioeconomic status (SES). Although largest proportion of patients continued to make their first contact with community services, the latter failed to refer cases of psychosis to the EI service despite making a large number of mostly non-cases (for psychosis). The intervention had no direct effect on total DUP, R-DUP or H-DUP. After controlling for diagnosis and SES, post-intervention, R-DUP remained significantly lower for patients making first contact with the emergency service of the parent institute.
CONCLUSIONS: The intervention failed to reduce R-DUP for patients making contact with or referred from community services and most patients still used hospital resources to enter treatment at the EI service.

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Year:  2014        PMID: 24902532     DOI: 10.1007/s00127-014-0893-1

Source DB:  PubMed          Journal:  Soc Psychiatry Psychiatr Epidemiol        ISSN: 0933-7954            Impact factor:   4.328


  27 in total

1.  Early detection strategies for untreated first-episode psychosis.

Authors:  J O Johannessen; T H McGlashan; T K Larsen; M Horneland; I Joa; S Mardal; R Kvebaek; S Friis; I Melle; S Opjordsmoen; E Simonsen; H Ulrik; P Vaglum
Journal:  Schizophr Res       Date:  2001-08-01       Impact factor: 4.939

Review 2.  Treating psychosis: is there more to early intervention than intervening early?

Authors:  A M Malla; R M Norman
Journal:  Can J Psychiatry       Date:  2001-09       Impact factor: 4.356

3.  A Canadian programme for early intervention in non-affective psychotic disorders.

Authors:  Ashok Malla; Ross Norman; Terry McLean; Derek Scholten; Laurel Townsend
Journal:  Aust N Z J Psychiatry       Date:  2003-08       Impact factor: 5.744

4.  Principles of educational outreach ('academic detailing') to improve clinical decision making.

Authors:  S B Soumerai; J Avorn
Journal:  JAMA       Date:  1990-01-26       Impact factor: 56.272

5.  Reducing the duration of untreated psychosis and changing help-seeking behaviour in Singapore.

Authors:  Siow-Ann Chong; S Mythily; Swapna Verma
Journal:  Soc Psychiatry Psychiatr Epidemiol       Date:  2005-08-16       Impact factor: 4.328

6.  The role of treatment delay in predicting 5-year outcomes in an early intervention program.

Authors:  R M G Norman; R Manchanda; D Windell; R Harricharan; S Northcott; L Hassall
Journal:  Psychol Med       Date:  2011-07-18       Impact factor: 7.723

Review 7.  EPPIC: an evolving system of early detection and optimal management.

Authors:  P D McGorry; J Edwards; C Mihalopoulos; S M Harrigan; H J Jackson
Journal:  Schizophr Bull       Date:  1996       Impact factor: 9.306

8.  Determinants of help-seeking and system related components of delay in the treatment of first-episode psychosis.

Authors:  Laura Bechard-Evans; Norbert Schmitz; Sherezad Abadi; Ridha Joober; Suzanne King; Ashok Malla
Journal:  Schizophr Res       Date:  2007-08-24       Impact factor: 4.939

9.  Reducing duration of untreated psychosis: care pathways to early intervention in psychosis services.

Authors:  Max Birchwood; Charlotte Connor; Helen Lester; Paul Patterson; Nick Freemantle; Max Marshall; David Fowler; Shôn Lewis; Peter Jones; Tim Amos; Linda Everard; Swaran P Singh
Journal:  Br J Psychiatry       Date:  2013-05-23       Impact factor: 9.319

10.  REDIRECT: cluster randomised controlled trial of GP training in first-episode psychosis.

Authors:  Helen Lester; Max Birchwood; Nick Freemantle; Maria Michail; Lynda Tait
Journal:  Br J Gen Pract       Date:  2009-06       Impact factor: 5.386

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  6 in total

Review 1.  From early intervention in psychosis to youth mental health reform: a review of the evolution and transformation of mental health services for young people.

Authors:  Ashok Malla; Srividya Iyer; Patrick McGorry; Mary Cannon; Helen Coughlan; Swaran Singh; Peter Jones; Ridha Joober
Journal:  Soc Psychiatry Psychiatr Epidemiol       Date:  2015-12-19       Impact factor: 4.328

2.  Disparities in Access to Early Psychosis Intervention Services: Comparison of Service Users and Nonusers in Health Administrative Data.

Authors:  Kelly K Anderson; Ross Norman; Arlene G MacDougall; Jordan Edwards; Lena Palaniyappan; Cindy Lau; Paul Kurdyak
Journal:  Can J Psychiatry       Date:  2018-03-21       Impact factor: 4.356

3.  Baby or bathwater? Referrals of "non-cases" in a targeted early identification intervention for psychosis.

Authors:  Gerald Jordan; Miriam Kinkaid; Srividya N Iyer; Ridha Joober; Karen Goldberg; Ashok Malla; Jai L Shah
Journal:  Soc Psychiatry Psychiatr Epidemiol       Date:  2018-03-14       Impact factor: 4.328

4.  Sex Differences in Clinical and Functional Outcomes among Patients Treated in an Early Intervention Service for Psychotic Disorders: An Observational Study.

Authors:  Manish Dama; Franz Veru; Norbert Schmitz; Jai Shah; Srividya Iyer; Ridha Joober; Ashok Malla
Journal:  Can J Psychiatry       Date:  2019-06-12       Impact factor: 4.356

Review 5.  Improving access to specialized care for first-episode psychosis: an ecological model.

Authors:  Aubrey M Moe; Ellen B Rubinstein; Colin J Gallagher; David M Weiss; Amanda Stewart; Nicholas Jk Breitborde
Journal:  Risk Manag Healthc Policy       Date:  2018-08-30

6.  Can We Reduce the Duration of Untreated Psychosis? A Systematic Review and Meta-Analysis of Controlled Interventional Studies.

Authors:  Dominic Oliver; Cathy Davies; Georgia Crossland; Steffiany Lim; George Gifford; Philip McGuire; Paolo Fusar-Poli
Journal:  Schizophr Bull       Date:  2018-10-17       Impact factor: 9.306

  6 in total

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