Literature DB >> 24900447

Discovery of Natural Phenols as G Protein-Coupled Receptor-35 (GPR35) Agonists.

Huayun Deng1, Haibei Hu1, Shizhang Ling1, Ann M Ferrie1, Ye Fang1.   

Abstract

We report the discovery and characterization of natural phenols as G protein-coupled receptor-35 (GPR35) agonists. Pharmacological characterization using label-free dynamic mass redistribution and Tango β-arrestin translocation assays revealed that GPR35-active natural phenols are divergent in their biased agonism.

Entities:  

Keywords:  GPR35; biased agonism; ellagic acid; natural phenols

Year:  2012        PMID： 24900447      PMCID： PMC4025658          DOI： 10.1021/ml2003058

Source DB:  PubMed          Journal:  ACS Med Chem Lett        ISSN： 1948-5875            Impact factor:   4.345


  21 in total

1.  Kynurenic acid as a ligand for orphan G protein-coupled receptor GPR35.

Authors:  Jinghong Wang; Nicole Simonavicius; Xiaosu Wu; Gayathri Swaminath; Jeff Reagan; Hui Tian; Lei Ling
Journal:  J Biol Chem       Date:  2006-06-05       Impact factor: 5.157

2.  Resonant waveguide grating biosensor for living cell sensing.

Authors:  Ye Fang; Ann M Ferrie; Norman H Fontaine; John Mauro; Jitendra Balakrishnan
Journal:  Biophys J       Date:  2006-06-09       Impact factor: 4.033

3.  Zaprinast, a well-known cyclic guanosine monophosphate-specific phosphodiesterase inhibitor, is an agonist for GPR35.

Authors:  Yasuhito Taniguchi; Hiroko Tonai-Kachi; Katsuhiro Shinjo
Journal:  FEBS Lett       Date:  2006-08-17       Impact factor: 4.124

4.  Characteristics of dynamic mass redistribution of epidermal growth factor receptor signaling in living cells measured with label-free optical biosensors.

Authors:  Ye Fang; Ann M Ferrie; Norman H Fontaine; Po Ki Yuen
Journal:  Anal Chem       Date:  2005-09-01       Impact factor: 6.986

5.  Tyrphostin analogs are GPR35 agonists.

Authors:  Huayun Deng; Haibei Hu; Ye Fang
Journal:  FEBS Lett       Date:  2011-05-17       Impact factor: 4.124

6.  G-protein-coupled receptor 35 is a target of the asthma drugs cromolyn disodium and nedocromil sodium.

Authors:  Yuhua Yang; Jenny Ying-Lin Lu; Xiaosu Wu; Shamin Summer; John Whoriskey; Christiaan Saris; Jeff D Reagan
Journal:  Pharmacology       Date:  2010-06-19       Impact factor: 2.547

7.  5-Nitro-2-(3-phenylpropylamino)benzoic acid is a GPR35 agonist.

Authors:  Yasuhito Taniguchi; Hiroko Tonai-Kachi; Katsuhiro Shinjo
Journal:  Pharmacology       Date:  2008-09-26       Impact factor: 2.547

8.  Cloning of a G-protein-coupled receptor that shows an activity to transform NIH3T3 cells and is expressed in gastric cancer cells.

Authors:  Shun-ichiro Okumura; Hiroko Baba; Tatsuro Kumada; Koji Nanmoku; Hirofumi Nakajima; Yasushi Nakane; Koshiro Hioki; Kazuhiro Ikenaka
Journal:  Cancer Sci       Date:  2004-02       Impact factor: 6.716

9.  Pomegranate juice consumption for 3 years by patients with carotid artery stenosis reduces common carotid intima-media thickness, blood pressure and LDL oxidation.

Authors:  Michael Aviram; Mira Rosenblat; Diana Gaitini; Samy Nitecki; Aaron Hoffman; Leslie Dornfeld; Nina Volkova; Dita Presser; Judith Attias; Harley Liker; Tony Hayek
Journal:  Clin Nutr       Date:  2004-06       Impact factor: 7.324

10.  Identification of genes related to heart failure using global gene expression profiling of human failing myocardium.

Authors:  Kyung-Duk Min; Masanori Asakura; Yulin Liao; Kenji Nakamaru; Hidetoshi Okazaki; Tomoko Takahashi; Kazunori Fujimoto; Shin Ito; Ayako Takahashi; Hiroshi Asanuma; Satoru Yamazaki; Tetsuo Minamino; Shoji Sanada; Osamu Seguchi; Atsushi Nakano; Yosuke Ando; Toshiaki Otsuka; Hidehiko Furukawa; Tadashi Isomura; Seiji Takashima; Naoki Mochizuki; Masafumi Kitakaze
Journal:  Biochem Biophys Res Commun       Date:  2010-01-25       Impact factor: 3.575
View more
  8 in total

1.  SAR Studies of N-[2-(1H-Tetrazol-5-yl)phenyl]benzamide Derivatives as Potent G Protein-Coupled Receptor-35 Agonists.

Authors:  Lai Wei; Tao Hou; Chang Lu; Jixia Wang; Xiuli Zhang; Ye Fang; Yaopeng Zhao; Jiatao Feng; Jiaqi Li; Lala Qu; Hai-Long Piao; Xinmiao Liang
Journal:  ACS Med Chem Lett       Date:  2018-04-09       Impact factor: 4.345

2.  High-throughput identification and characterization of novel, species-selective GPR35 agonists.

Authors:  Zaynab Neetoo-Isseljee; Amanda E MacKenzie; Craig Southern; Jeff Jerman; Edward G McIver; Nicholas Harries; Debra L Taylor; Graeme Milligan
Journal:  J Pharmacol Exp Ther       Date:  2012-12-21       Impact factor: 4.030

3.  The antiallergic mast cell stabilizers lodoxamide and bufrolin as the first high and equipotent agonists of human and rat GPR35.

Authors:  Amanda E MacKenzie; Gianluigi Caltabiano; Toby C Kent; Laura Jenkins; Jennifer E McCallum; Brian D Hudson; Stuart A Nicklin; Lindsay Fawcett; Rachel Markwick; Steven J Charlton; Graeme Milligan
Journal:  Mol Pharmacol       Date:  2013-10-10       Impact factor: 4.436

4.  Synthesis and Agonistic Activity at the GPR35 of 5,6-Dihydroxyindole-2-carboxylic Acid Analogues.

Authors:  Huayun Deng; Ye Fang
Journal:  ACS Med Chem Lett       Date:  2012-06-06       Impact factor: 4.345

5.  Discovery of new muscarinic acetylcholine receptor antagonists from Scopolia tangutica.

Authors:  Nana Du; Yanfang Liu; Xiuli Zhang; Jixia Wang; Jianqiang Zhao; Jian He; Han Zhou; Lijuan Mei; Xinmiao Liang
Journal:  Sci Rep       Date:  2017-04-07       Impact factor: 4.379

6.  The Three Catecholics Benserazide, Catechol and Pyrogallol are GPR35 Agonists.

Authors:  Huayun Deng; Ye Fang
Journal:  Pharmaceuticals (Basel)       Date:  2013-04-08

7.  Label-free cell phenotypic profiling decodes the composition and signaling of an endogenous ATP-sensitive potassium channel.

Authors:  Haiyan Sun; Ying Wei; Huayun Deng; Qiaojie Xiong; Min Li; Joydeep Lahiri; Ye Fang
Journal:  Sci Rep       Date:  2014-05-12       Impact factor: 4.379

8.  Evidence for the Existence of a CXCL17 Receptor Distinct from GPR35.

Authors:  Nurul A S Binti Mohd Amir; Amanda E Mackenzie; Laura Jenkins; Karim Boustani; Marston C Hillier; Tomoko Tsuchiya; Graeme Milligan; James E Pease
Journal:  J Immunol       Date:  2018-06-06       Impact factor: 5.422
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.