| Literature DB >> 24896250 |
Dhaval Kolte1, Krishnaswami Vijayaraghavan, Sahil Khera, Domenic A Sica, William H Frishman.
Abstract
Magnesium, the fourth most abundant cation in the human body, is involved in several essential physiological, biochemical, and cellular processes regulating cardiovascular function. It plays a critical role in modulating vascular smooth muscle tone, endothelial cell function, and myocardial excitability and is thus central to the pathogenesis of several cardiovascular disorders such as hypertension, atherosclerosis, coronary artery disease, congestive heart failure, and cardiac arrhythmias. This review discusses the vasodilatory, anti-inflammatory, anti-ischemic, and antiarrhythmic properties of magnesium and its current role in the prevention and treatment of cardiovascular disorders.Entities:
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Year: 2014 PMID: 24896250 DOI: 10.1097/CRD.0000000000000003
Source DB: PubMed Journal: Cardiol Rev ISSN: 1061-5377 Impact factor: 2.644