Literature DB >> 24896127

Probing the average local structure of biomolecules using small-angle scattering and scaling laws.

Max C Watson1, Joseph E Curtis2.   

Abstract

Small-angle neutron and x-ray scattering have become invaluable tools for probing the nanostructure of molecules in solution. It was recently shown that the definite integral of the scattering profile exhibits a scaling (power-law) behavior with respect to molecular mass. We derive the origin of this relationship, and discuss how the integrated scattering profile can be used to identify differing levels of disorder over local ≲30 Å length scales. We apply our analysis to globular and intrinsically disordered proteins.
Copyright © 2014 Biophysical Society. Published by Elsevier Inc. All rights reserved.

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Year:  2014        PMID： 24896127      PMCID： PMC4052260          DOI： 10.1016/j.bpj.2014.03.050

Source DB:  PubMed          Journal:  Biophys J        ISSN： 0006-3495            Impact factor:   4.033


  31 in total

1.  The packing density in proteins: standard radii and volumes.

Authors:  J Tsai; R Taylor; C Chothia; M Gerstein
Journal:  J Mol Biol       Date:  1999-07-02       Impact factor: 5.469

Review 2.  Toward a taxonomy of the denatured state: small angle scattering studies of unfolded proteins.

Authors:  Ian S Millett; Sebastian Doniach; Kevin W Plaxco
Journal:  Adv Protein Chem       Date:  2002

3.  Random-coil behavior and the dimensions of chemically unfolded proteins.

Authors:  Jonathan E Kohn; Ian S Millett; Jaby Jacob; Bojan Zagrovic; Thomas M Dillon; Nikolina Cingel; Robin S Dothager; Soenke Seifert; P Thiyagarajan; Tobin R Sosnick; M Zahid Hasan; Vijay S Pande; Ingo Ruczinski; Sebastian Doniach; Kevin W Plaxco
Journal:  Proc Natl Acad Sci U S A       Date:  2004-08-16       Impact factor: 11.205

4.  SAXS study of the PIR domain from the Grb14 molecular adaptor: a natively unfolded protein with a transient structure primer?

Authors:  K Moncoq; I Broutin; C T Craescu; P Vachette; A Ducruix; D Durand
Journal:  Biophys J       Date:  2004-10-01       Impact factor: 4.033

5.  Scalable molecular dynamics with NAMD.

Authors:  James C Phillips; Rosemary Braun; Wei Wang; James Gumbart; Emad Tajkhorshid; Elizabeth Villa; Christophe Chipot; Robert D Skeel; Laxmikant Kalé; Klaus Schulten
Journal:  J Comput Chem       Date:  2005-12       Impact factor: 3.376

6.  Structural characterization of flexible proteins using small-angle X-ray scattering.

Authors:  Pau Bernadó; Efstratios Mylonas; Maxim V Petoukhov; Martin Blackledge; Dmitri I Svergun
Journal:  J Am Chem Soc       Date:  2007-04-06       Impact factor: 15.419

7.  Evidence for a coiled-coil interaction mode of disordered proteins from bacterial type III secretion systems.

Authors:  Anastasia D Gazi; Marina Bastaki; Spyridoula N Charova; Eirini A Gkougkoulia; Efthymios A Kapellios; Nicholas J Panopoulos; Michael Kokkinidis
Journal:  J Biol Chem       Date:  2008-10-03       Impact factor: 5.157

8.  Structure of tumor suppressor p53 and its intrinsically disordered N-terminal transactivation domain.

Authors:  Mark Wells; Henning Tidow; Trevor J Rutherford; Phineus Markwick; Malene Ringkjobing Jensen; Efstratios Mylonas; Dmitri I Svergun; Martin Blackledge; Alan R Fersht
Journal:  Proc Natl Acad Sci U S A       Date:  2008-04-07       Impact factor: 11.205

9.  Human regulatory protein Ki-1/57 has characteristics of an intrinsically unstructured protein.

Authors:  Gustavo C Bressan; Júlio C Silva; Júlio C Borges; Dario O Dos Passos; Carlos H I Ramos; Iris L Torriani; Jörg Kobarg
Journal:  J Proteome Res       Date:  2008-09-13       Impact factor: 4.466

Review 10.  Biophysical characterization of intrinsically disordered proteins.

Authors:  David Eliezer
Journal:  Curr Opin Struct Biol       Date:  2009-01-21       Impact factor: 6.809
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  7 in total

1.  The PTEN Tumor Suppressor Forms Homodimers in Solution.

Authors:  Frank Heinrich; Srinivas Chakravarthy; Hirsh Nanda; Antonella Papa; Pier Paolo Pandolfi; Alonzo H Ross; Rakesh K Harishchandra; Arne Gericke; Mathias Lösche
Journal:  Structure       Date:  2015-08-20       Impact factor: 5.006

2.  Commonly used FRET fluorophores promote collapse of an otherwise disordered protein.

Authors:  Joshua A Riback; Micayla A Bowman; Adam M Zmyslowski; Kevin W Plaxco; Patricia L Clark; Tobin R Sosnick
Journal:  Proc Natl Acad Sci U S A       Date:  2019-04-16       Impact factor: 11.205

3.  Decoupling of size and shape fluctuations in heteropolymeric sequences reconciles discrepancies in SAXS vs. FRET measurements.

Authors:  Gustavo Fuertes; Niccolò Banterle; Kiersten M Ruff; Aritra Chowdhury; Davide Mercadante; Christine Koehler; Michael Kachala; Gemma Estrada Girona; Sigrid Milles; Ankur Mishra; Patrick R Onck; Frauke Gräter; Santiago Esteban-Martín; Rohit V Pappu; Dmitri I Svergun; Edward A Lemke
Journal:  Proc Natl Acad Sci U S A       Date:  2017-07-17       Impact factor: 11.205

4.  Quarterly intrinsic disorder digest (April-May-June, 2014).

Authors:  Shelly DeForte; Vladimir N Uversky
Journal:  Intrinsically Disord Proteins       Date:  2017-03-01

5.  Preparing monodisperse macromolecular samples for successful biological small-angle X-ray and neutron-scattering experiments.

Authors:  Cy M Jeffries; Melissa A Graewert; Clément E Blanchet; David B Langley; Andrew E Whitten; Dmitri I Svergun
Journal:  Nat Protoc       Date:  2016-10-06       Impact factor: 13.491

Review 6.  Water as a Good Solvent for Unfolded Proteins: Folding and Collapse are Fundamentally Different.

Authors:  Patricia L Clark; Kevin W Plaxco; Tobin R Sosnick
Journal:  J Mol Biol       Date:  2020-02-07       Impact factor: 5.469

7.  The Disease Associated Tau35 Fragment has an Increased Propensity to Aggregate Compared to Full-Length Tau.

Authors:  Chen Lyu; Stefano Da Vela; Youssra Al-Hilaly; Karen E Marshall; Richard Thorogate; Dmitri Svergun; Louise C Serpell; Annalisa Pastore; Diane P Hanger
Journal:  Front Mol Biosci       Date:  2021-10-28
  7 in total

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