| Literature DB >> 2489087 |
V T Forsyth1, A Mahendrasingam, W J Pigram, R J Greenall, K Bellamy, W Fuller, S A Mason.
Abstract
Interactions with water are crucial to the conformation assumed by the DNA double helix. The location of water around the D conformation has been investigated in a neutron fibre diffraction study which shows that water is ordered in the minor groove of the DNA. The D conformation is important since its occurrence is limited to specific DNA base pair sequences which have been identified as functionally significant. This study is of particular interest because the D conformation has not been reported in single crystal studies of oligonucleotides.Entities:
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Year: 1989 PMID： 2489087 DOI： 10.1016/0141-8130(89)90075-5
Source DB: PubMed Journal: Int J Biol Macromol ISSN： 0141-8130 Impact factor: 6.953