Literature DB >> 24889644

Anti-HIV drug particles may overcome lymphatic drug insufficiency and associated HIV persistence.

Jennifer P Freeling1, Rodney J Y Ho2.   

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Year:  2014        PMID: 24889644      PMCID: PMC4078825          DOI: 10.1073/pnas.1406554111

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


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  5 in total

1.  Persistent HIV-1 replication is associated with lower antiretroviral drug concentrations in lymphatic tissues.

Authors:  Courtney V Fletcher; Kathryn Staskus; Stephen W Wietgrefe; Meghan Rothenberger; Cavan Reilly; Jeffrey G Chipman; Greg J Beilman; Alexander Khoruts; Ann Thorkelson; Thomas E Schmidt; Jodi Anderson; Katherine Perkey; Mario Stevenson; Alan S Perelson; Daniel C Douek; Ashley T Haase; Timothy W Schacker
Journal:  Proc Natl Acad Sci U S A       Date:  2014-01-27       Impact factor: 11.205

2.  Afferent pathways of lymph flow within the popliteal node in sheep.

Authors:  T J Heath; R L Kerlin; H J Spalding
Journal:  J Anat       Date:  1986-12       Impact factor: 2.610

3.  Optimization of lipid-indinavir complexes for localization in lymphoid tissues of HIV-infected macaques.

Authors:  Loren Kinman; Tot Bui; Kay Larsen; Che-Chung Tsai; David Anderson; William R Morton; Shiu-Lok Hu; Rodney J Y Ho
Journal:  J Acquir Immune Defic Syndr       Date:  2006-06       Impact factor: 3.731

4.  Novel Gd nanoparticles enhance vascular contrast for high-resolution magnetic resonance imaging.

Authors:  Tot Bui; Jeff Stevenson; John Hoekman; Shanrong Zhang; Kenneth Maravilla; Rodney J Y Ho
Journal:  PLoS One       Date:  2010-09-30       Impact factor: 3.240

5.  Lipid-drug association enhanced HIV-1 protease inhibitor indinavir localization in lymphoid tissues and viral load reduction: a proof of concept study in HIV-2287-infected macaques.

Authors:  Loren Kinman; Scott J Brodie; Che Chung Tsai; Tot Bui; Kay Larsen; Ann Schmidt; David Anderson; William R Morton; Shiu-Lok Hu; Rodney J Y Ho
Journal:  J Acquir Immune Defic Syndr       Date:  2003-12-01       Impact factor: 3.731

  5 in total
  21 in total

1.  Pharmacokinetic stability of macrocyclic peptide triazole HIV-1 inactivators alone and in liposomes.

Authors:  Rachna Aneja; Antonella Grigoletto; Aakansha Nangarlia; Adel A Rashad; Steven Wrenn; Jeffrey M Jacobson; Gianfranco Pasut; Irwin Chaiken
Journal:  J Pept Sci       Date:  2019-02-27       Impact factor: 1.905

Review 2.  From sewer to saviour - targeting the lymphatic system to promote drug exposure and activity.

Authors:  Natalie L Trevaskis; Lisa M Kaminskas; Christopher J H Porter
Journal:  Nat Rev Drug Discov       Date:  2015-10-16       Impact factor: 84.694

Review 3.  The lymph node microenvironment and its role in the progression of metastatic cancer.

Authors:  Ethel R Pereira; Dennis Jones; Keehoon Jung; Timothy P Padera
Journal:  Semin Cell Dev Biol       Date:  2015-01-22       Impact factor: 7.727

4.  Mechanism-based pharmacokinetic (MBPK) models describe the complex plasma kinetics of three antiretrovirals delivered by a long-acting anti-HIV drug combination nanoparticle formulation.

Authors:  John C Kraft; Lisa A McConnachie; Josefin Koehn; Loren Kinman; Jianguo Sun; Ann C Collier; Carol Collins; Danny D Shen; Rodney J Y Ho
Journal:  J Control Release       Date:  2018-02-10       Impact factor: 9.776

Review 5.  Translation of combination nanodrugs into nanomedicines: lessons learned and future outlook.

Authors:  Qingxin Mu; Jesse Yu; Lisa A McConnachie; John C Kraft; Yu Gao; Gaurav K Gulati; Rodney J Y Ho
Journal:  J Drug Target       Date:  2018-01-10       Impact factor: 5.121

Review 6.  Nanotechnology approaches to eradicating HIV reservoirs.

Authors:  Shijie Cao; Kim A Woodrow
Journal:  Eur J Pharm Biopharm       Date:  2018-06-04       Impact factor: 5.571

Review 7.  Nanodrug formulations to enhance HIV drug exposure in lymphoid tissues and cells: clinical significance and potential impact on treatment and eradication of HIV/AIDS.

Authors:  Jingwei Shao; John C Kraft; Bowen Li; Jesse Yu; Jennifer Freeling; Josefin Koehn; Rodney Jy Ho
Journal:  Nanomedicine (Lond)       Date:  2016-02-19       Impact factor: 5.307

Review 8.  The Lymphatic System in Disease Processes and Cancer Progression.

Authors:  Timothy P Padera; Eelco F J Meijer; Lance L Munn
Journal:  Annu Rev Biomed Eng       Date:  2016-02-05       Impact factor: 9.590

9.  Lymph node effective vascular permeability and chemotherapy uptake.

Authors:  Eelco F J Meijer; Cedric Blatter; Ivy X Chen; Echoe Bouta; Dennis Jones; Ethel R Pereira; Keehoon Jung; Benjamin J Vakoc; James W Baish; Timothy P Padera
Journal:  Microcirculation       Date:  2017-08       Impact factor: 2.628

10.  Long-Acting Profile of 4 Drugs in 1 Anti-HIV Nanosuspension in Nonhuman Primates for 5 Weeks After a Single Subcutaneous Injection.

Authors:  Lisa A McConnachie; Loren M Kinman; Josefin Koehn; John C Kraft; Sarah Lane; Wonsok Lee; Ann C Collier; Rodney J Y Ho
Journal:  J Pharm Sci       Date:  2018-03-13       Impact factor: 3.534

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