| Literature DB >> 24888447 |
Giorgi Gogoladze1, Maia Grigolava, Boris Vishnepolsky, Mindia Chubinidze, Patrice Duroux, Marie-Paule Lefranc, Malak Pirtskhalava.
Abstract
The Database of Antimicrobial Activity and Structure of Peptides (DBAASP) is a manually curated database for those peptides for which antimicrobial activity against particular targets has been evaluated experimentally. The database is a depository of complete information on: the chemical structure of peptides; target species; target object of cell; peptide antimicrobial/haemolytic/cytotoxic activities; and experimental conditions at which activities were estimated. The DBAASP search page allows the user to search peptides according to their structural characteristics, complexity type (monomer, dimer and two-peptide), source, synthesis type (ribosomal, nonribosomal and synthetic) and target species. The database prediction algorithm provides a tool for rational design of new antimicrobial peptides. DBAASP is accessible at http://www.biomedicine.org.ge/dbaasp/.Keywords: antimicrobial activity; antimicrobial peptide; database; haemolytic/cytotoxic activity
Mesh:
Substances:
Year: 2014 PMID: 24888447 DOI: 10.1111/1574-6968.12489
Source DB: PubMed Journal: FEMS Microbiol Lett ISSN: 0378-1097 Impact factor: 2.742