Literature DB >> 24885634

Fluorination of flavones and chromones using elemental fluorine.

Inna Vints1, Shlomo Rozen.   

Abstract

Flavonoids are abundant micronutrients in our diet, possessing various biological activities. Fluorine was successfully added across the double bond of various flavones and chromones. The difluoro derivative products were easily dehydrofluorinated to form the corresponding 3-fluoroflavones and 3-fluorochromones.

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Year:  2014        PMID： 24885634     DOI： 10.1021/jo5009542

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  4 in total

1.  Catalytic, Enantioselective 1,2-Difluorination of Cinnamamides.

Authors:  Moriana K Haj; Steven M Banik; Eric N Jacobsen
Journal:  Org Lett       Date:  2019-04-09       Impact factor: 6.005

2.  Catalytic, Diastereoselective 1,2-Difluorination of Alkenes.

Authors:  Steven M Banik; Jonathan William Medley; Eric N Jacobsen
Journal:  J Am Chem Soc       Date:  2016-04-12       Impact factor: 15.419

3.  Inhibitory effects against α-glucosidase and α-amylase of the flavonoids-rich extract from Scutellaria baicalensis shoots and interpretation of structure-activity relationship of its eight flavonoids by a refined assign-score method.

Authors:  Ke Li; Fan Yao; Qiang Xue; Hang Fan; Lingguang Yang; Xiang Li; Liwei Sun; Yujun Liu
Journal:  Chem Cent J       Date:  2018-07-12       Impact factor: 4.215

4.  The Chemistry of Short-Lived α-Fluorocarbocations.

Authors:  Shlomo Rozen; Inna Vints; Ana Lerner; Oded Hod; Edward N Brothers; Salvador Moncho
Journal:  J Org Chem       Date:  2021-02-22       Impact factor: 4.354
  4 in total

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