Literature DB >> 24883105

Pelvic floor muscle rehabilitation for patients with lifelong premature ejaculation: a novel therapeutic approach.

Antonio L Pastore1, Giovanni Palleschi2, Andrea Fuschi3, Cristina Maggioni3, Rocco Rago4, Alessandro Zucchi5, Elisabetta Costantini5, Antonio Carbone2.   

Abstract

OBJECTIVES: Premature ejaculation is the most common male sexual disorder. The aim of the study was to evaluate the possible therapeutic role of pelvic floor muscle rehabilitation in patients affected by lifelong premature ejaculation.
METHODS: We treated 40 men with lifelong premature ejaculation, reporting, a baseline intravaginal ejaculatory latency time (IELT) ≤ 1 min, with 12-week pelvic floor muscle rehabilitation.
RESULTS: At the end of the rehabilitation, mean IELTs were calculated to evaluate the effectiveness of the therapy. At the end of the treatment, 33 (82.5%) of the 40 patients gained control of their ejaculatory reflex, with a mean IELT of 146.2 s (range: 123.6-152.4 s). A total of 13 out of 33 (39%) patients were evaluated at 6 months follow up, and they maintained a significant IELT (112.6 s) compared with their initial IELT (mean 39.8 s).
CONCLUSIONS: The results obtained in our subjects treated with pelvic floor rehabilitation are promising. This therapy represents an important cost reduction compared with the standard treatment (selective serotonin reuptake inhibitors). Based on the present data, we propose pelvic floor muscle rehabilitation as a new, viable therapeutic option for the treatment of premature ejaculation.

Entities:  

Keywords:  biofeedback; electro-stimulation; intravaginal ejaculatory latency time; premature ejaculation

Year:  2014        PMID: 24883105      PMCID: PMC4003840          DOI: 10.1177/1756287214523329

Source DB:  PubMed          Journal:  Ther Adv Urol        ISSN: 1756-2872


  16 in total

Review 1.  The role of the levator ani muscle in evacuation, sexual performance and pelvic floor disorders.

Authors:  A Shafik
Journal:  Int Urogynecol J Pelvic Floor Dysfunct       Date:  2000-12

2.  A multinational population survey of intravaginal ejaculation latency time.

Authors:  Marcel D Waldinger; Paul Quinn; Maria Dilleen; Rajiv Mundayat; Dave H Schweitzer; Mitradev Boolell
Journal:  J Sex Med       Date:  2005-07       Impact factor: 3.802

3.  The controversial role of phosphodiesterase type 5 inhibitors in the treatment of premature ejaculation.

Authors:  Emmanuele A Jannini; Chris McMahon; Juza Chen; Antonio Aversa; Michael Perelman
Journal:  J Sex Med       Date:  2011-08       Impact factor: 3.802

4.  A new treatment for premature ejaculation: the rehabilitation of the pelvic floor.

Authors:  G La Pera; A Nicastro
Journal:  J Sex Marital Ther       Date:  1996

5.  The Premature Ejaculation Prevalence and Attitudes (PEPA) survey: prevalence, comorbidities, and professional help-seeking.

Authors:  Hartmut Porst; Francesco Montorsi; Raymond C Rosen; Lisa Gaynor; Stephanie Grupe; Joseph Alexander
Journal:  Eur Urol       Date:  2006-07-26       Impact factor: 20.096

6.  Chronic prostatitis in premature ejaculation: a cohort study in 153 men.

Authors:  Rany Shamloul; Abdelrahman el-Nashaar
Journal:  J Sex Med       Date:  2006-01       Impact factor: 3.802

7.  A prospective randomized study to compare pelvic floor rehabilitation and dapoxetine for treatment of lifelong premature ejaculation.

Authors:  A L Pastore; G Palleschi; A Leto; L Pacini; F Iori; C Leonardo; A Carbone
Journal:  Int J Androl       Date:  2012-02-09

8.  Single- and multiple-dose pharmacokinetics of dapoxetine hydrochloride, a novel agent for the treatment of premature ejaculation.

Authors:  Nishit B Modi; Mark J Dresser; Mary Simon; Denise Lin; Dhaval Desai; Suneel Gupta
Journal:  J Clin Pharmacol       Date:  2006-03       Impact factor: 3.126

Review 9.  WITHDRAWN: Physical therapies for prevention of urinary and faecal incontinence in adults.

Authors:  J Hay-Smith; P Herbison; S Mørkved
Journal:  Cochrane Database Syst Rev       Date:  2007-10-17

Review 10.  Prevalence, characteristics and implications of premature ejaculation/rapid ejaculation.

Authors:  Stanley E Althof
Journal:  J Urol       Date:  2006-03       Impact factor: 7.450

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  5 in total

1.  Ejaculatory training lengthens the ejaculation latency and facilitates the functioning of the spinal generator for ejaculation of rats with rapid ejaculation.

Authors:  M de L Rodríguez-Peña; G Rodríguez-Manzo; M Carro-Juárez
Journal:  Int J Impot Res       Date:  2016-10-27       Impact factor: 2.896

2.  Transcutaneous functional electrical stimulation-a novel therapy for premature ejaculation: results of a proof of concept study.

Authors:  Arik Shechter; E C Serefoglu; Tal Gollan; Shmuel Springer; Gideon Meiry; Boaz Appel; Ilan Gruenwald
Journal:  Int J Impot Res       Date:  2019-09-30       Impact factor: 2.896

Review 3.  Current and emerging treatment options for premature ejaculation.

Authors:  Murat Gul; Kadir Bocu; Ege Can Serefoglu
Journal:  Nat Rev Urol       Date:  2022-08-25       Impact factor: 16.430

4.  Pelvic muscle floor rehabilitation as a therapeutic option in lifelong premature ejaculation: long-term outcomes.

Authors:  Antonio Luigi Pastore; Giovanni Palleschi; Andrea Fuschi; Yazan Al Salhi; Alessandro Zucchi; Giorgio Bozzini; Ester Illiano; Elisabetta Costantini; Antonio Carbone
Journal:  Asian J Androl       Date:  2018 Nov-Dec       Impact factor: 3.285

5.  Rhodiola rosea, folic acid, zinc and biotin (EndEP®) is able to improve ejaculatory control in patients affected by lifelong premature ejaculation: Results from a phase I-II study.

Authors:  Tommaso Cai; Paolo Verze; Paolo Massenio; Daniele Tiscione; Gianni Malossini; Luigi Cormio; Giuseppe Carrieri; Vincenzo Mirone
Journal:  Exp Ther Med       Date:  2016-08-12       Impact factor: 2.447

  5 in total

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