Literature DB >> 24882889

A concise synthesis of highly substituted imidazoles via copper-mediated oxidative C-H functionalization.

Amit N Pandya1, Devendra K Agrawal2.   

Abstract

We herein report a simple and concise route for the synthesis of highly substituted imidazole derivatives via copper-mediated oxidative C-H functionalization in good to high yields. The advantage of the reaction lies in its mild reaction conditions and readily available starting materials.

Entities:  

Keywords:  C–H functionalization; Imidazole; Oxidative dehydrogenation

Year:  2014        PMID： 24882889      PMCID： PMC4034134          DOI： 10.1016/j.tetlet.2014.01.136

Source DB:  PubMed          Journal:  Tetrahedron Lett        ISSN： 0040-4039            Impact factor:   2.415


  7 in total

1.  Facile synthesis of polysubstituted oxazoles via a copper-catalyzed tandem oxidative cyclization.

Authors:  Changfeng Wan; Jintang Zhang; Sujing Wang; Jinmin Fan; Zhiyong Wang
Journal:  Org Lett       Date:  2010-05-21       Impact factor: 6.005

2.  Synthesis of multisubstituted imidazoles via copper-catalyzed [3 + 2] cycloadditions.

Authors:  Dong Tang; Ping Wu; Xiang Liu; Yong-Xin Chen; Shuai-Bo Guo; Wen-Lin Chen; Jia-Gen Li; Bao-Hua Chen
Journal:  J Org Chem       Date:  2013-02-21       Impact factor: 4.354

3.  A simple and efficient approach to the synthesis of 2-phenylquinazolines via sp(3) C-H functionalization.

Authors:  Jintang Zhang; Dapeng Zhu; Chenmin Yu; Changfeng Wan; Zhiyong Wang
Journal:  Org Lett       Date:  2010-06-18       Impact factor: 6.005

4.  Highly efficient copper-catalyzed nitro-Mannich type reaction: cross-dehydrogenative-coupling between sp3 C-H bond and sp3 C-H bond.

Authors:  Zhiping Li; Chao-Jun Li
Journal:  J Am Chem Soc       Date:  2005-03-23       Impact factor: 15.419

5.  N-H insertion reactions of primary ureas: the synthesis of highly substituted imidazolones and imidazoles from diazocarbonyls.

Authors:  Sang-Hyeup Lee; Kazuhiro Yoshida; Hana Matsushita; Bruce Clapham; Guido Koch; Jürg Zimmermann; Kim D Janda
Journal:  J Org Chem       Date:  2004-12-10       Impact factor: 4.354

6.  Diversity synthesis via C-H bond functionalization: concept-guided development of new C-arylation methods for imidazoles.

Authors:  Bengü Sezen; Dalibor Sames
Journal:  J Am Chem Soc       Date:  2003-09-03       Impact factor: 15.419

7.  Cross-dehydrogenative coupling (CDC): exploring C-C bond formations beyond functional group transformations.

Authors:  Chao-Jun Li
Journal:  Acc Chem Res       Date:  2009-02-17       Impact factor: 22.384
  7 in total
  2 in total

1.  Silver-Mediated Synthesis of Indolizines via Oxidative C-H functionalization and 5- endo-dig cyclization.

Authors:  Amit N Pandya; James T Fletcher; Eric M Villa; Devendra K Agrawal
Journal:  Tetrahedron Lett       Date:  2014-12-10       Impact factor: 2.415

2.  A Simple and Efficient Approach for the Synthesis of 2-Aminated Quinazoline Derivatives via Metal Free Oxidative Annulation.

Authors:  Amit N Pandya; Eric M Villa; E Jeffrey North
Journal:  Tetrahedron Lett       Date:  2017-02-12       Impact factor: 2.415
  2 in total

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