Literature DB >> 23409756

Synthesis of multisubstituted imidazoles via copper-catalyzed [3 + 2] cycloadditions.

Dong Tang1, Ping Wu, Xiang Liu, Yong-Xin Chen, Shuai-Bo Guo, Wen-Lin Chen, Jia-Gen Li, Bao-Hua Chen.   

Abstract

A simple route for the synthesis of imidazole derivatives via copper-catalyzed [3 + 2] cycloaddition reaction is described. This strategy has achieved high regioselectivity and used oxygen as an oxidant without the addition of expensive catalysts to provide moderate to good yields.

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Year:  2013        PMID: 23409756     DOI: 10.1021/jo302555z

Source DB:  PubMed          Journal:  J Org Chem        ISSN: 0022-3263            Impact factor:   4.354


  2 in total

Review 1.  Current advances in the synthesis and biological potencies of tri- and tetra-substituted 1H-imidazoles.

Authors:  Majid M Heravi; Mansoureh Daraie; Vahideh Zadsirjan
Journal:  Mol Divers       Date:  2015-04-12       Impact factor: 2.943

2.  A concise synthesis of highly substituted imidazoles via copper-mediated oxidative C-H functionalization.

Authors:  Amit N Pandya; Devendra K Agrawal
Journal:  Tetrahedron Lett       Date:  2014-03-05       Impact factor: 2.415

  2 in total

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