Literature DB >> 24876754

Clinicopathologic factors influencing the accuracy of EUS for superficial esophageal carcinoma.

Jung Im Jung1, Gwang Ha Kim1, Hoseok I1, Do Youn Park1, Tae Kyun Kim1, Young Hwa Cho1, Yong Wan Sung1, Mun Ki Choi1, Bong Eun Lee1, Geun Am Song1.   

Abstract

AIM: To identify clinicopathologic factors influencing the accuracy of a high-frequency catheter probe endoscopic ultrasonography (EUS) for superficial esophageal carcinomas (SECs).
METHODS: A total of 126 patients with endoscopically suspected SEC, who underwent EUS and curative treatment at Pusan National University Hospital during 2005-2013, were enrolled. We reviewed the medical records of the 126 patients and compared EUS findings with histopathologic results according to clinicopathologic factors.
RESULTS: A total of 114 lesions in 113 patients were included in the final analysis. The EUS assessment of tumor invasion depth was accurate in 78.9% (90/114) patients. Accuracy did not differ according to histologic type, tumor differentiation, tumor location, or macroscopic shape. However, accuracy significantly decreased for tumors ≥ 3 cm in size (P = 0.002). Overestimation and underestimation of the invasion depth occurred for 11 (9.6%) and 13 lesions (11.4%), respectively. In multivariate analyses, tumor size ≥ 3 cm was the only factor significantly associated with EUS accuracy (P = 0.031), and was specifically associated with the underestimation of invasion depth.
CONCLUSION: EUS using a high-frequency catheter probe generally provides highly accurate assessments of SEC invasion depth, but its accuracy decreases for tumors ≥ 3 cm.

Entities:  

Keywords:  Accuracy; Endoscopic ultrasonography; Esophageal cancer

Mesh:

Year:  2014        PMID: 24876754      PMCID: PMC4033471          DOI: 10.3748/wjg.v20.i20.6322

Source DB:  PubMed          Journal:  World J Gastroenterol        ISSN: 1007-9327            Impact factor:   5.742


  30 in total

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