Literature DB >> 24873841

Human breast milk and the gastrointestinal innate immune system.

Brett M Jakaitis1, Patricia W Denning2.   

Abstract

The gastrointestinal (GI) tract is a large potential portal for multiple infectious agents to enter the human body. The GI system performs multiple functions as part of the neonate's innate immune system, providing critical defense during a vulnerable period. Multiple mechanisms and actions are enhanced by the presence of human breast milk. Bioactive factors found in human milk work together to create and maintain an optimal and healthy environment, allowing the intestines to deliver ideal nutrition to the host and afford protection by a variety of mechanisms.
Copyright © 2014 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Antimicrobial peptides; Bioactive factors; Commensal bacteria; Human breast milk; Intestinal microbiome; Lactoferrin; Mucosal innate immune system

Mesh:

Year:  2014        PMID: 24873841      PMCID: PMC4414019          DOI: 10.1016/j.clp.2014.02.011

Source DB:  PubMed          Journal:  Clin Perinatol        ISSN: 0095-5108            Impact factor:   3.430


  101 in total

Review 1.  Securing the immune tightrope: mononuclear phagocytes in the intestinal lamina propria.

Authors:  Chen Varol; Ehud Zigmond; Steffen Jung
Journal:  Nat Rev Immunol       Date:  2010-06       Impact factor: 53.106

2.  Soluble factors from Lactobacillus GG activate MAPKs and induce cytoprotective heat shock proteins in intestinal epithelial cells.

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Authors:  E J Mayer; R F Hamman; E C Gay; D C Lezotte; D A Savitz; G J Klingensmith
Journal:  Diabetes       Date:  1988-12       Impact factor: 9.461

Review 5.  Lactoferrin for prevention of neonatal infections.

Authors:  Paolo Manzoni; Michael Mostert; Mauro Stronati
Journal:  Curr Opin Infect Dis       Date:  2011-06       Impact factor: 4.915

6.  Modulation of human intestinal epithelial cell IL-8 secretion by human milk factors.

Authors:  Erika C Claud; Tor Savidge; W Allen Walker
Journal:  Pediatr Res       Date:  2003-03       Impact factor: 3.756

7.  Interleukin-10 in human milk.

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8.  Transforming growth factor-beta 1, macrophage inflammatory protein-1 alpha, and interleukin-8 gene expression is lower in stimulated human neonatal compared with adult mononuclear cells.

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Journal:  Blood       Date:  1994-07-01       Impact factor: 22.113

9.  Commensal anaerobic gut bacteria attenuate inflammation by regulating nuclear-cytoplasmic shuttling of PPAR-gamma and RelA.

Authors:  Denise Kelly; Jamie I Campbell; Timothy P King; George Grant; Emmelie A Jansson; Alistair G P Coutts; Sven Pettersson; Shaun Conway
Journal:  Nat Immunol       Date:  2003-12-21       Impact factor: 25.606

10.  Lactoferrin down-regulates the LPS-induced cytokine production in monocytic cells via NF-kappa B.

Authors:  Liliana Håversen; Bertil G Ohlsson; Mirjana Hahn-Zoric; Lars A Hanson; Inger Mattsby-Baltzer
Journal:  Cell Immunol       Date:  2002-12       Impact factor: 4.868

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  39 in total

Review 1.  The crucial role of early-life gut microbiota in the development of type 1 diabetes.

Authors:  He Zhou; Lin Sun; Siwen Zhang; Xue Zhao; Xiaokun Gang; Guixia Wang
Journal:  Acta Diabetol       Date:  2020-07-25       Impact factor: 4.280

2.  Early-life lactoferrin intervention modulates the colonic microbiota, colonic microbial metabolites and intestinal function in suckling piglets.

Authors:  Ping Hu; Fangzhou Zhao; Jing Wang; Weiyun Zhu
Journal:  Appl Microbiol Biotechnol       Date:  2020-05-22       Impact factor: 4.813

Review 3.  To start or not: Factors to consider when implementing routine probiotic use in the NICU.

Authors:  Maria E Barbian; Rachel Buckle; Patricia Wei Denning; Ravi Mangal Patel
Journal:  Early Hum Dev       Date:  2019-06-10       Impact factor: 2.079

Review 4.  Knowledge gaps in late-onset neonatal sepsis in preterm neonates: a roadmap for future research.

Authors:  Swantje Voller; H Rob Taal; Serife Kurul; Kinga Fiebig; Robert B Flint; Irwin K M Reiss; Helmut Küster; Sinno H P Simons
Journal:  Pediatr Res       Date:  2021-09-08       Impact factor: 3.756

Review 5.  Pathogenesis of NEC: Role of the innate and adaptive immune response.

Authors:  Timothy L Denning; Amina M Bhatia; Andrea F Kane; Ravi M Patel; Patricia W Denning
Journal:  Semin Perinatol       Date:  2016-12-09       Impact factor: 3.300

Review 6.  Regulation of inflammation by lipid mediators in oral diseases.

Authors:  S Sommakia; O J Baker
Journal:  Oral Dis       Date:  2016-08-04       Impact factor: 3.511

7.  Peptides Derived from In Vitro and In Vivo Digestion of Human Milk Are Immunomodulatory in THP-1 Human Macrophages.

Authors:  Ningjian Liang; Robert L Beverly; Brian P Scottoline; David C Dallas
Journal:  J Nutr       Date:  2022-01-11       Impact factor: 4.687

Review 8.  Interaction of Streptococcus agalactiae and Cellular Innate Immunity in Colonization and Disease.

Authors:  Sybille Landwehr-Kenzel; Philipp Henneke
Journal:  Front Immunol       Date:  2014-10-29       Impact factor: 7.561

9.  Effect of a Semi-Purified Oligosaccharide-Enriched Fraction from Caprine Milk on Barrier Integrity and Mucin Production of Co-Culture Models of the Small and Large Intestinal Epithelium.

Authors:  Alicia M Barnett; Nicole C Roy; Warren C McNabb; Adrian L Cookson
Journal:  Nutrients       Date:  2016-05-06       Impact factor: 5.717

10.  Transfer of Maternal Immune Cells by Breastfeeding: Maternal Cytotoxic T Lymphocytes Present in Breast Milk Localize in the Peyer's Patches of the Nursed Infant.

Authors:  Allison Cabinian; Daniel Sinsimer; May Tang; Osvaldo Zumba; Hetali Mehta; Annmarie Toma; Derek Sant'Angelo; Yasmina Laouar; Amale Laouar
Journal:  PLoS One       Date:  2016-06-10       Impact factor: 3.240

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