Literature DB >> 24868111

Metabolic profiling in diabetes.

Karsten Suhre1.   

Abstract

Metabolic profiling, or metabolomics, has developed into a mature science in recent years. It has major applications in the study of metabolic disorders. This review addresses issues relevant to the choice of the metabolomics platform, study design and data analysis in diabetes research, and presents recent advances using metabolomics in the identification of markers for altered metabolic pathways, biomarker discovery, challenge studies, metabolic markers of drug efficacy and off-target effects. The role of genetic variance and intermediate metabolic phenotypes and its relevance to diabetes research is also addressed. ©  2014 Society for Endocrinology.

Entities:  

Keywords:  diabetes; glucose metabolism; insulin resistance; lipid; metabolism

Mesh：

Substances：

Year:  2014        PMID： 24868111     DOI： 10.1530/JOE-14-0024

Source DB:  PubMed          Journal:  J Endocrinol        ISSN： 0022-0795            Impact factor:   4.286


  32 in total

1.  Novel insights into development of diabetic bladder disorder provided by metabolomic analysis of the rat nondiabetic and diabetic detrusor and urothelial layer.

Authors:  Yi Wang; Gary G Deng; Kelvin P Davies
Journal:  Am J Physiol Endocrinol Metab       Date:  2016-06-28       Impact factor: 4.310

Review 2.  Emerging risk biomarkers in cardiovascular diseases and disorders.

Authors:  Ravi Kant Upadhyay
Journal:  J Lipids       Date:  2015-04-08

3.  A new metabolite panel test for identification of patients with impaired glucose tolerance? Analysis of the article by Cobb et al.

Authors:  Andreas Pfützner
Journal:  J Diabetes Sci Technol       Date:  2014-11-26

Review 4.  Key elements of metabolomics in the study of biomarkers of diabetes.

Authors:  Jerzy Adamski
Journal:  Diabetologia       Date:  2016-10-06       Impact factor: 10.122

5.  Individual variability in human blood metabolites identifies age-related differences.

Authors:  Romanas Chaleckis; Itsuo Murakami; Junko Takada; Hiroshi Kondoh; Mitsuhiro Yanagida
Journal:  Proc Natl Acad Sci U S A       Date:  2016-03-28       Impact factor: 11.205

6.  Plasma metabolomic profiles in association with type 2 diabetes risk and prevalence in Chinese adults.

Authors:  Danxia Yu; Steven C Moore; Charles E Matthews; Yong-Bing Xiang; Xianglan Zhang; Yu-Tang Gao; Wei Zheng; Xiao-Ou Shu
Journal:  Metabolomics       Date:  2015-11-07       Impact factor: 4.290

Review 7.  Metabolomics in childhood diabetes.

Authors:  Brigitte I Frohnert; Marian J Rewers
Journal:  Pediatr Diabetes       Date:  2015-09-30       Impact factor: 4.866

8.  Plasma amino acid and metabolite signatures tracking diabetes progression in the UCD-T2DM rat model.

Authors:  Brian D Piccolo; James L Graham; Kimber L Stanhope; Oliver Fiehn; Peter J Havel; Sean H Adams
Journal:  Am J Physiol Endocrinol Metab       Date:  2016-04-19       Impact factor: 4.310

9.  Impact of Long-Term Poor and Good Glycemic Control on Metabolomics Alterations in Type 1 Diabetic People.

Authors:  Tumpa Dutta; Yogish C Kudva; Xuan-Mai T Persson; Louis A Schenck; G Charles Ford; Ravinder J Singh; Rickey Carter; K Sreekumaran Nair
Journal:  J Clin Endocrinol Metab       Date:  2016-01-21       Impact factor: 5.958

10.  5-Aminoimidazole-4-carboxamide ribonucleoside-mediated adenosine monophosphate-activated protein kinase activation induces protective innate responses in bacterial endophthalmitis.

Authors:  Ajay Kumar; Shailendra Giri; Ashok Kumar
Journal:  Cell Microbiol       Date:  2016-07-26       Impact factor: 3.715
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