| Literature DB >> 24865682 |
Marli S Santana1, Wuelton M Monteiro2, Mônica R F Costa2, Vanderson S Sampaio2, Marcelo A M Brito2, Marcus V G Lacerda2, Maria G C Alecrim2.
Abstract
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is one of the most common human genetic abnormalities, and it has a significant prevalence in the male population (X chromosome linked). The purpose of this study was to estimate the frequency of impaired fasting glucose and diabetes among G6PD-deficient persons in Manaus, Brazil, an area in the Western Brazilian Amazon to which malaria is endemic. Glucose-6-phosphate dehydrogenase-deficient males had more impaired fasting glucose and diabetes. This feature could be used as a screening tool for G6PD-deficient persons who are unable to use primaquine for the radical cure of Plasmodium vivax malaria. © The American Society of Tropical Medicine and Hygiene.Entities:
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Year: 2014 PMID: 24865682 PMCID: PMC4080572 DOI: 10.4269/ajtmh.13-0032
Source DB: PubMed Journal: Am J Trop Med Hyg ISSN: 0002-9637 Impact factor: 2.345