Literature DB >> 24862605

Bilateral subhyaloid haemorrhage in a conscious patient: a new spectrum of ocular involvement by Plasmodium falciparum.

Nasar Abdali1, Azharuddin Mohammed Malik1, Md Dilawez Shamim1, Syed Wajahat Ali Rizvi2.   

Abstract

A 24-year-old woman presented with a history of high-grade fever with rigours since 3 days and bilateral sudden loss of vision since 6 h. She was conscious, oriented and her vitals were stable. She had a temperature of 101°F, anaemia, thrombocytopaenia, normal white cell count and moderate splenomegaly. On testing visual activity, she could only perceive hand movements although her pupils were bilaterally equal, and normal in size and reaction. On indirect ophthalmoscopy, optic discs were normal bilaterally; however, fovea of both eyes was masked by subhyaloid haemorrhage. Peripheral smear showed gametocytes of Plasmodium falciparum. The patient was started on arteminsinin-combined therapy and advised to be in propped-up position to help resolution of the haemorrhage. The patient was afebrile in 4 days and follow-up fundus examination showed gradual resolution of the haemorrhage. After two months, the patient regained normal visual acuity in both eyes; however, it took nearly 3 months for complete resolution of the haemorrhage. 2014 BMJ Publishing Group Ltd.

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Year:  2014        PMID: 24862605      PMCID: PMC4039889          DOI: 10.1136/bcr-2013-202811

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  13 in total

1.  Falciparum malaria induced retrobulbar neuritis.

Authors:  Vijay P Kale; L S Bichile; S Bajpai
Journal:  J Postgrad Med       Date:  2004 Apr-Jun       Impact factor: 1.476

2.  Severe subconjunctival haemorrhage associated with malaria.

Authors:  D Kaimbo Wa Kaimbo; L Missotten
Journal:  Bull Soc Belge Ophtalmol       Date:  1999

3.  Quinine idiosyncracy leading to bilateral subhyaloid haemorrhage.

Authors:  M R Jain; S Mehta
Journal:  Indian J Ophthalmol       Date:  1977-07       Impact factor: 1.848

4.  A review of the spectrum of clinical ocular fundus findings in P. falciparum malaria in African children with a proposed classification and grading system.

Authors:  S Lewallen; S P Harding; J Ajewole; W E Schulenburg; M E Molyneux; K Marsh; S Usen; N J White; T E Taylor
Journal:  Trans R Soc Trop Med Hyg       Date:  1999 Nov-Dec       Impact factor: 2.184

5.  The incidence and outcome of neurological abnormalities in childhood cerebral malaria: a long-term follow-up of 62 survivors.

Authors:  F S Bondi
Journal:  Trans R Soc Trop Med Hyg       Date:  1992 Jan-Feb       Impact factor: 2.184

6.  The pattern of neurological sequelae of childhood cerebral malaria among survivors in Calabar, Nigeria.

Authors:  M M Meremikwu; A A Asindi; E Ezedinachi
Journal:  Cent Afr J Med       Date:  1997-08

7.  Ophthalmoscopic abnormalities in adults with falciparum malaria.

Authors:  D K Kochar; B L Kumawat; I Thanvi; A Joshi; S P Vyas
Journal:  QJM       Date:  1998-12

8.  Ophthalmoscopic findings in adult patients with severe falciparum malaria.

Authors:  Salil A Mehta; Abdul Samad Ansari; Prakash Jiandani
Journal:  Ocul Immunol Inflamm       Date:  2008 Sep-Oct       Impact factor: 3.070

Review 9.  Neurological sequelae of cerebral malaria in children.

Authors:  D R Brewster; D Kwiatkowski; N J White
Journal:  Lancet       Date:  1990-10-27       Impact factor: 79.321

10.  Retinal hemorrhage, a common sign of prognostic significance in cerebral malaria.

Authors:  S Looareesuwan; D A Warrell; N J White; P Chanthavanich; M J Warrell; S Chantaratherakitti; S Changswek; L Chongmankongcheep; C Kanchanaranya
Journal:  Am J Trop Med Hyg       Date:  1983-09       Impact factor: 2.345

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