Literature DB >> 24853931

Silencing synapses with DREADDs.

Hu Zhu1, Bryan L Roth2.   

Abstract

In this issue of Neuron, Stachniak et al. (2014) determine that the chemogenetic silencer hM4Di-DREADD suppresses presynaptic glutamate release, and by generating an axon-targeted hM4Di variant they demonstrate that it can be used to locally silence synaptic transmission in neural circuits.
Copyright © 2014 Elsevier Inc. All rights reserved.

Entities:  

Mesh：

Year:  2014        PMID： 24853931      PMCID： PMC4109642          DOI： 10.1016/j.neuron.2014.05.002

Source DB:  PubMed          Journal:  Neuron        ISSN： 0896-6273            Impact factor:   17.173


  16 in total

1.  Tonically active protein kinase A regulates neurotransmitter release at the squid giant synapse.

Authors:  S Hilfiker; A J Czernik; P Greengard; G J Augustine
Journal:  J Physiol       Date:  2001-02-15       Impact factor: 5.182

2.  Thinking about the brain.

Authors:  F H Crick
Journal:  Sci Am       Date:  1979-09       Impact factor: 2.142

3.  Chemogenetic inactivation of ventral hippocampal glutamatergic neurons disrupts consolidation of contextual fear memory.

Authors:  Hu Zhu; Kristen E Pleil; Daniel J Urban; Sheryl S Moy; Thomas L Kash; Bryan L Roth
Journal:  Neuropsychopharmacology       Date:  2014-02-14       Impact factor: 7.853

4.  Rapid, reversible activation of AgRP neurons drives feeding behavior in mice.

Authors:  Michael J Krashes; Shuichi Koda; ChianPing Ye; Sarah C Rogan; Andrew C Adams; Daniel S Cusher; Eleftheria Maratos-Flier; Bryan L Roth; Bradford B Lowell
Journal:  J Clin Invest       Date:  2011-04       Impact factor: 14.808

5.  Impaired respiratory and body temperature control upon acute serotonergic neuron inhibition.

Authors:  Russell S Ray; Andrea E Corcoran; Rachael D Brust; Jun Chul Kim; George B Richerson; Eugene Nattie; Susan M Dymecki
Journal:  Science       Date:  2011-07-29       Impact factor: 47.728

6.  Chemogenetic synaptic silencing of neural circuits localizes a hypothalamus→midbrain pathway for feeding behavior.

Authors:  Tevye J Stachniak; Anirvan Ghosh; Scott M Sternson
Journal:  Neuron       Date:  2014-04-24       Impact factor: 17.173

7.  Deconstruction of a neural circuit for hunger.

Authors:  Deniz Atasoy; J Nicholas Betley; Helen H Su; Scott M Sternson
Journal:  Nature       Date:  2012-08-09       Impact factor: 49.962

8.  Transient neuronal inhibition reveals opposing roles of indirect and direct pathways in sensitization.

Authors:  Susan M Ferguson; Daniel Eskenazi; Masago Ishikawa; Matthew J Wanat; Paul E M Phillips; Yan Dong; Bryan L Roth; John F Neumaier
Journal:  Nat Neurosci       Date:  2010-12-05       Impact factor: 24.884

9.  Genetic identification of a neural circuit that suppresses appetite.

Authors:  Matthew E Carter; Marta E Soden; Larry S Zweifel; Richard D Palmiter
Journal:  Nature       Date:  2013-10-13       Impact factor: 49.962

10.  Designer receptors show role for ventral pallidum input to ventral tegmental area in cocaine seeking.

Authors:  Stephen V Mahler; Elena M Vazey; Jacob T Beckley; Colby R Keistler; Ellen M McGlinchey; Jennifer Kaufling; Steven P Wilson; Karl Deisseroth; John J Woodward; Gary Aston-Jones
Journal:  Nat Neurosci       Date:  2014-03-02       Impact factor: 24.884
View more
  34 in total

1.  Defined Cell Types in Superior Colliculus Make Distinct Contributions to Prey Capture Behavior in the Mouse.

Authors:  Jennifer L Hoy; Hannah I Bishop; Cristopher M Niell
Journal:  Curr Biol       Date:  2019-11-21       Impact factor: 10.834

2.  Mouse genetic differences in voluntary wheel running, adult hippocampal neurogenesis and learning on the multi-strain-adapted plus water maze.

Authors:  Jennifer R Merritt; Justin S Rhodes
Journal:  Behav Brain Res       Date:  2014-11-27       Impact factor: 3.332

3.  Disrupting the medial prefrontal cortex alters hippocampal sequences during deliberative decision making.

Authors:  Brandy Schmidt; Anneke A Duin; A David Redish
Journal:  J Neurophysiol       Date:  2019-03-20       Impact factor: 2.714

Review 4.  Autonomic dysreflexia after spinal cord injury: Systemic pathophysiology and methods of management.

Authors:  Khalid C Eldahan; Alexander G Rabchevsky
Journal:  Auton Neurosci       Date:  2017-05-08       Impact factor: 3.145

5.  Chemogenetic inhibition reveals midline thalamic nuclei and thalamo-accumbens projections mediate cocaine-seeking in rats.

Authors:  Amanda M Wunsch; Lindsay M Yager; Elizabeth A Donckels; Calvin T Le; John F Neumaier; Susan M Ferguson
Journal:  Eur J Neurosci       Date:  2017-07-26       Impact factor: 3.386

6.  Chemogenetic modulation of the parafacial respiratory group influences the recruitment of abdominal activity during REM sleep.

Authors:  Annette Pisanski; Xiuqing Ding; Nils A Koch; Silvia Pagliardini
Journal:  Sleep       Date:  2020-05-12       Impact factor: 5.849

7.  Transforming Sensory Cues into Aversive Emotion via Septal-Habenular Pathway.

Authors:  Guang-Wei Zhang; Li Shen; Wen Zhong; Ying Xiong; Li I Zhang; Huizhong W Tao
Journal:  Neuron       Date:  2018-08-16       Impact factor: 17.173

8.  Heterogeneous transgene expression in the retinas of the TH-RFP, TH-Cre, TH-BAC-Cre and DAT-Cre mouse lines.

Authors:  H E Vuong; L Pérez de Sevilla Müller; C N Hardi; D G McMahon; N C Brecha
Journal:  Neuroscience       Date:  2015-08-31       Impact factor: 3.590

9.  A New Population of Parvocellular Oxytocin Neurons Controlling Magnocellular Neuron Activity and Inflammatory Pain Processing.

Authors:  Marina Eliava; Meggane Melchior; H Sophie Knobloch-Bollmann; Jérôme Wahis; Miriam da Silva Gouveia; Yan Tang; Alexandru Cristian Ciobanu; Rodrigo Triana Del Rio; Lena C Roth; Ferdinand Althammer; Virginie Chavant; Yannick Goumon; Tim Gruber; Nathalie Petit-Demoulière; Marta Busnelli; Bice Chini; Linette L Tan; Mariela Mitre; Robert C Froemke; Moses V Chao; Günter Giese; Rolf Sprengel; Rohini Kuner; Pierrick Poisbeau; Peter H Seeburg; Ron Stoop; Alexandre Charlet; Valery Grinevich
Journal:  Neuron       Date:  2016-03-03       Impact factor: 17.173

10.  The PVN enhances cardiorespiratory responses to acute hypoxia via input to the nTS.

Authors:  Brian C Ruyle; Diana Martinez; Cheryl M Heesch; David D Kline; Eileen M Hasser
Journal:  Am J Physiol Regul Integr Comp Physiol       Date:  2019-09-11       Impact factor: 3.619
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.