F Scheel1, M Hufeland, B Sinn, N P Haas, C Perka, J H Schröder. 1. Sektion Hüft- und Beckenchirurgie, Centrum für Muskuloskeletale Chirurgie, Klinik für Orthopädie und Klinik für Unfall- und Wiederherstellungschirurgie, Charité-Universitätsmedizin Berlin, Campus Virchow-Klinikum, Augustenburger Platz 1, 13353, Berlin, Deutschland.
Abstract
BACKGROUND: We report on a 60-year-old immunocompetent German male patient without risk factors, who had been suffering from pain in the right hip for 8 months. DIAGNOSTICS: Radiographs showed destruction of the femoral head with a collapse of the main weight-bearing area, which was interpreted as femoral head necrosis. THERAPY: A cement-free total hip prosthesis was then implanted. The femoral head was sent for routine histological analysis and PCR amplification yielded a positive result for Mycobacterium tuberculosis complex DNA, leading to immediate guideline-based tuberculostatic treatment. CONCLUSION: Tuberculosis should be considered as a differential diagnosis in the case of destruction of the femoral head, especially in immunocompromised patients, patients with a foreign background or destructive osteoarthritis of the hip with an atypical course. Antibiotic treatment is necessary postoperatively. Under this therapy, a good clinical outcome can be expected comparable to that achieved in patients with primary osteoarthritis without infection.
BACKGROUND: We report on a 60-year-old immunocompetent German male patient without risk factors, who had been suffering from pain in the right hip for 8 months. DIAGNOSTICS: Radiographs showed destruction of the femoral head with a collapse of the main weight-bearing area, which was interpreted as femoral head necrosis. THERAPY: A cement-free total hip prosthesis was then implanted. The femoral head was sent for routine histological analysis and PCR amplification yielded a positive result for Mycobacterium tuberculosis complex DNA, leading to immediate guideline-based tuberculostatic treatment. CONCLUSION: Tuberculosis should be considered as a differential diagnosis in the case of destruction of the femoral head, especially in immunocompromised patients, patients with a foreign background or destructive osteoarthritis of the hip with an atypical course. Antibiotic treatment is necessary postoperatively. Under this therapy, a good clinical outcome can be expected comparable to that achieved in patients with primary osteoarthritis without infection.
Authors: Konstantinos N Malizos; Apostolos H Karantanas; Sokratis E Varitimidis; Zoe H Dailiana; Konstantinos Bargiotas; Thomas Maris Journal: Eur J Radiol Date: 2007-06-06 Impact factor: 3.528
Authors: Piotr Walczak; Kazimierz Rąpała; Mirosława Nowak-Misiak; Roman Pykało; Aleksandra Truszczyńska Journal: Ortop Traumatol Rehabil Date: 2012 Mar-Apr
Authors: Dimitri De Vuyst; Filip Vanhoenacker; Jan Gielen; Anja Bernaerts; Arthur M De Schepper Journal: Eur Radiol Date: 2002-08-02 Impact factor: 5.315