Literature DB >> 24849180

Outcomes of pancreaticoduodenectomy: where should we focus our efforts on improving outcomes?

Erin G Brown1, Anthony Yang1, Robert J Canter1, Richard J Bold1.   

Abstract

IMPORTANCE: Changes in health care reimbursement policy have led to an era in which hospitals are motivated to improve quality of care while simultaneously reducing costs. Research demonstrating the most efficient means to target costs may have a positive effect on patient quality of life and the overburdened health care system.
OBJECTIVE: To evaluate the effect of hospital length of stay (LOS) and the occurrence of postoperative complications on total charges in patients undergoing elective pancreaticoduodenectomy. DESIGN, SETTING, AND PATIENTS: We performed a retrospective review of 89 cases identified in an institutional database of patients who underwent elective pancreaticoduodenectomy at an academic tertiary care center from December 1, 2007, through May 31, 2012. MAIN OUTCOMES AND MEASURES: Occurrence of postoperative and inpatient complications, LOS, incidence of readmission within 60 days of discharge, and hospital charges from initial postoperative hospitalization. Linear regression analysis was performed comparing LOS with hospital charges.
RESULTS: Thirty-four of 89 patients (38%) developed postoperative complications. Mean and median LOSs were 12 and 8 days, respectively. The LOS was significantly related to postoperative complications. Of the 34 patients who developed complications, the mean LOS was 19 days compared with 7 days for those patients not developing complications (P < .001). Only 2 of 55 patients (4%) without complications were readmitted to the hospital, whereas 13 of 34 patients (38%) with complications required readmission. Perioperative hospital charges were significantly related to LOS (R² = 0.840, R = 0.917). For those patients without complications, linear regression demonstrated a daily hospital charge of $11,612 (R² = 0.923, R = 0.961). However, for those patients with complications, the optimal relationship between LOS and hospital charges was exponential (R² = 0.832). CONCLUSIONS AND RELEVANCE: Prolonged LOS is associated with increased total charges, but given the exponential increase in charges, the complication itself has an effect on increased charges above and beyond that of a prolonged hospitalization. The drive to reduce LOS after pancreaticoduodenectomy has minimal effect on overall charges to the patient. Efforts should be directed instead at reducing complications because this has a much more significant effect on financial outcomes.

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Year:  2014        PMID: 24849180     DOI: 10.1001/jamasurg.2014.151

Source DB:  PubMed          Journal:  JAMA Surg        ISSN: 2168-6254            Impact factor:   14.766


  18 in total

1.  Preoperative Nutritional Assessment Using the Controlling Nutritional Status Score to Predict Pancreatic Fistula After Pancreaticoduodenectomy.

Authors:  Masashi Utsumi; Hideki Aoki; Seichi Nagahisa; Seitaro Nishimura; Yuta Une; Yuji Kimura; Fumitaka Taniguchi; Takashi Arata; Koh Katsuda; Kohji Tanakaya
Journal:  In Vivo       Date:  2020 Jul-Aug       Impact factor: 2.155

2.  Delayed Gastric Emptying After Pancreaticoduodenectomy: an Analysis of Risk Factors and Cost.

Authors:  Joshua D Eisenberg; Ernest L Rosato; Harish Lavu; Charles J Yeo; Jordan M Winter
Journal:  J Gastrointest Surg       Date:  2015-07-14       Impact factor: 3.452

Review 3.  Stents for the prevention of pancreatic fistula following pancreaticoduodenectomy.

Authors:  Zhiyong Dong; Jing Xu; Zhen Wang; Maxim S Petrov
Journal:  Cochrane Database Syst Rev       Date:  2016-05-06

Review 4.  Comparative effectiveness of biliary brush cytology and intraductal biopsy for detection of malignant biliary strictures: a systematic review and meta-analysis.

Authors:  Udayakumar Navaneethan; Basile Njei; Vennisvasanth Lourdusamy; Rajesh Konjeti; John J Vargo; Mansour A Parsi
Journal:  Gastrointest Endosc       Date:  2014-11-01       Impact factor: 9.427

5.  A Cohort Study for Derivation and Validation of Early Detection of Pancreatic Fistula After Pancreaticoduodenectomy.

Authors:  Kazuki Takeishi; Takashi Maeda; Yo-Ichi Yamashita; Eiji Tsujita; Shinji Itoh; Norifumi Harimoto; Toru Ikegami; Tomoharu Yoshizumi; Ken Shirabe; Yoshihiko Maehara
Journal:  J Gastrointest Surg       Date:  2015-11-23       Impact factor: 3.452

6.  The attenuation value of preoperative computed tomography as a novel predictor for pancreatic fistula after pancreaticoduodenectomy.

Authors:  Takehiko Hanaki; Chihiro Uejima; Masataka Amisaki; Arai Yosuke; Naruo Tokuyasu; Soichiro Honjo; Teruhisa Sakamoto; Hiroaki Saito; Masahide Ikeguchi; Yoshiyuki Fujiwara
Journal:  Surg Today       Date:  2018-01-30       Impact factor: 2.549

7.  Hospital readmissions: necessary evil or preventable target for quality improvement.

Authors:  Erin G Brown; Debra Burgess; Chin-Shang Li; Robert J Canter; Richard J Bold
Journal:  Ann Surg       Date:  2014-10       Impact factor: 12.969

8.  Nomogram based on albumin and neutrophil-to-lymphocyte ratio for predicting postoperative complications after pancreaticoduodenectomy.

Authors:  Haoquan Huang; Chengli Wang; Fengtao Ji; Zhixiao Han; Hui Xu; Minghui Cao
Journal:  Gland Surg       Date:  2021-03

9.  Risk Factors and a New Prediction Model for Pancreatic Fistula After Pancreaticoduodenectomy.

Authors:  Jia-Yu Zhang; Jia Huang; Su-Ya Zhao; Xin Liu; Zhen-Cheng Xiong; Zhi-Ying Yang
Journal:  Risk Manag Healthc Policy       Date:  2021-05-10

10.  Risk factors for postoperative pancreatic fistula: Analysis of 539 successive cases of pancreaticoduodenectomy.

Authors:  Bing-Yang Hu; Tao Wan; Wen-Zhi Zhang; Jia-Hong Dong
Journal:  World J Gastroenterol       Date:  2016-09-14       Impact factor: 5.742

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