Literature DB >> 24848229

Natural products: DNA double whammy.

Kent S Gates1.   

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Year:  2014        PMID： 24848229     DOI： 10.1038/nchem.1965

Source DB:  PubMed          Journal:  Nat Chem        ISSN： 1755-4330            Impact factor:   24.427


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  11 in total

1.  Lomaiviticins A and B, potent antitumor antibiotics from Micromonospora lomaivitiensis.

Authors:  H He; W D Ding; V S Bernan; A D Richardson; C M Ireland; M Greenstein; G A Ellestad; G T Carter
Journal:  J Am Chem Soc       Date:  2001-06-06       Impact factor: 15.419

2.  Noncovalent DNA binding drives DNA alkylation by leinamycin: evidence that the Z,E-5-(thiazol-4-yl)-penta-2,4-dienone moiety of the natural product serves as an atypical DNA intercalator.

Authors:  Mostafa I Fekry; Jozsef Szekely; Sanjay Dutta; Leonid Breydo; Hong Zang; Kent S Gates
Journal:  J Am Chem Soc       Date:  2011-10-18       Impact factor: 15.419

Review 3.  Lessons from natural molecules.

Authors:  Jon Clardy; Christopher Walsh
Journal:  Nature       Date:  2004-12-16       Impact factor: 49.962

Review 4.  Natural products as sources of new drugs over the 30 years from 1981 to 2010.

Authors:  David J Newman; Gordon M Cragg
Journal:  J Nat Prod       Date:  2012-02-08       Impact factor: 4.050

Review 5.  An overview of chemical processes that damage cellular DNA: spontaneous hydrolysis, alkylation, and reactions with radicals.

Authors:  Kent S Gates
Journal:  Chem Res Toxicol       Date:  2009-11       Impact factor: 3.739

6.  Bioactivation as a model for drug design bioreductive alkylation.

Authors:  H W Moore
Journal:  Science       Date:  1977-08-05       Impact factor: 47.728

7.  Structures and biological properties of Kinamycin A, B, C, and D.

Authors:  S Omura; A Nakagawa; H Yamada; T Hata; A Furusaki
Journal:  Chem Pharm Bull (Tokyo)       Date:  1973-05       Impact factor: 1.645

8.  Diazo group electrophilicity in kinamycins and lomaiviticin A: potential insights into the molecular mechanism of antibacterial and antitumor activity.

Authors:  Radoslaw S Laufer; Gary I Dmitrienko
Journal:  J Am Chem Soc       Date:  2002-03-06       Impact factor: 15.419

9.  Isolation of lomaiviticins C-E, transformation of lomaiviticin C to lomaiviticin A, complete structure elucidation of lomaiviticin A, and structure-activity analyses.

Authors:  Christina M Woo; Nina E Beizer; Jeffrey E Janso; Seth B Herzon
Journal:  J Am Chem Soc       Date:  2012-09-10       Impact factor: 15.419

10.  The cytotoxicity of (-)-lomaiviticin A arises from induction of double-strand breaks in DNA.

Authors:  Laureen C Colis; Christina M Woo; Denise C Hegan; Zhenwu Li; Peter M Glazer; Seth B Herzon
Journal:  Nat Chem       Date:  2014-05-11       Impact factor: 24.427
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