Literature DB >> 24839615

Ex-translational function of tRNAs and their fragments in cancer.

Anna M Mleczko1, Piotr Celichowski1, Kamilla Bąkowska-Żywicka1.   

Abstract

Transfer RNA (tRNA) molecules are most commonly known as the molecular amino acids carriers and also because of the role they play in a protein biosynthesis process. However, tRNA biology has revealed stupendous levels of many unexpected discoveries that put a new light on tRNA function in different processes besides translation, like apoptosis or cancer development. In recent years various species of RNAs have been found differentially expressed in different types of cancer. In this review we focus our attention on tRNAs as well as on tRNA-derived small RNAs ex-translational functions in human cells in oncogenesis and oncobiology.

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Year:  2014        PMID: 24839615

Source DB:  PubMed          Journal:  Acta Biochim Pol        ISSN: 0001-527X            Impact factor:   2.149


  11 in total

1.  Emerging Roles of tRNA-derived Fragments in Viral Infections: The Case of Respiratory Syncytial Virus.

Authors:  Pavel Ivanov
Journal:  Mol Ther       Date:  2015-10       Impact factor: 11.454

2.  Identifying the ligated amino acid of archaeal tRNAs based on positions outside the anticodon.

Authors:  Tal Galili; Hila Gingold; Shaul Shaul; Yoav Benjamini
Journal:  RNA       Date:  2016-08-11       Impact factor: 4.942

3.  Reverse Transcription Past Products of Guanine Oxidation in RNA Leads to Insertion of A and C opposite 8-Oxo-7,8-dihydroguanine and A and G opposite 5-Guanidinohydantoin and Spiroiminodihydantoin Diastereomers.

Authors:  Anton Alenko; Aaron M Fleming; Cynthia J Burrows
Journal:  Biochemistry       Date:  2017-09-11       Impact factor: 3.162

Review 4.  tRNA fragments in human health and disease.

Authors:  Paul Anderson; Pavel Ivanov
Journal:  FEBS Lett       Date:  2014-09-16       Impact factor: 4.124

5.  tRNA-derived short RNAs bind to Saccharomyces cerevisiae ribosomes in a stress-dependent manner and inhibit protein synthesis in vitro.

Authors:  Kamilla Bąkowska-Żywicka; Marta Kasprzyk; Tomasz Twardowski
Journal:  FEMS Yeast Res       Date:  2016-09-07       Impact factor: 2.796

6.  Predicting transfer RNA gene activity from sequence and genome context.

Authors:  Bryan P Thornlow; Joel Armstrong; Andrew D Holmes; Jonathan M Howard; Russell B Corbett-Detig; Todd M Lowe
Journal:  Genome Res       Date:  2019-12-19       Impact factor: 9.043

Review 7.  Small Noncoding RNAs in Knee Osteoarthritis: The Role of MicroRNAs and tRNA-Derived Fragments.

Authors:  Julian Zacharjasz; Anna M Mleczko; Paweł Bąkowski; Tomasz Piontek; Kamilla Bąkowska-Żywicka
Journal:  Int J Mol Sci       Date:  2021-05-27       Impact factor: 5.923

8.  Characterization and selective incorporation of small non-coding RNAs in non-small cell lung cancer extracellular vesicles.

Authors:  Chuang Li; Fang Qin; Fen Hu; Hui Xu; Guihong Sun; Guang Han; Tao Wang; Mingxiong Guo
Journal:  Cell Biosci       Date:  2018-01-10       Impact factor: 7.133

Review 9.  The role of Transfer RNA-Derived Small RNAs (tsRNAs) in Digestive System Tumors.

Authors:  Ben-Gang Wang; Li-Rong Yan; Qian Xu; Xin-Ping Zhong
Journal:  J Cancer       Date:  2020-10-18       Impact factor: 4.207

10.  Expression and Diagnostic Value of tRNA-Derived Fragments Secreted by Extracellular Vesicles in Hypopharyngeal Carcinoma.

Authors:  Jian Xi; Zhiming Zeng; Xin Li; Xin Zhang; Jing Xu
Journal:  Onco Targets Ther       Date:  2021-07-14       Impact factor: 4.147

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