Qusay Haydour1, Fares Alahdab2, Magdoleen Farah2, Patricia Barrionuevo3, Anne E Vertigan4, Peter A Newcombe5, Tamara Pringsheim6, Anne B Chang7, Bruce K Rubin8, Lorcan McGarvey9, Kelly A Weir10, Kenneth W Altman11, Anthony Feinstein12, Mohammad Hassan Murad2, Richard S Irwin13. 1. Mayo Clinic, The Knowledge and Evaluation Research Unit and the Center for the Science of Health Care Delivery, Rochester, MN. Electronic address: q.haydour@gmail.com. 2. Mayo Clinic, The Knowledge and Evaluation Research Unit and the Center for the Science of Health Care Delivery, Rochester, MN. 3. Unidad de Conocimiento y Evidencia, Universidad Peruana Cayetano Heredia, Lima, Peru; Mayo Clinic, The Knowledge and Evaluation Research Unit and the Center for the Science of Health Care Delivery, Rochester, MN. 4. John Hunter Hospital, Department of Speech Pathology, Newcastle, NSW, Australia. 5. University of Queensland, School of Psychology, Brisbane, QLD, Australia. 6. University of Calgary, Calgary, AB, Canada. 7. Royal Children's Hospital and Menzies School of Health Research, Charles Darwin University, Brisbane, Brisbane, QLD, Australia. 8. Children's Hospital of Richmond and Virginia Commonwealth University, Richmond, VA. 9. Centre for Infection and Immunity, The Queen's University of Belfast, Belfast, Northern Ireland. 10. Royal Children's Hospital Department of Speech Pathology and Queensland Children's Medical Research Institute, The University of Queensland, Brisbane, QLD, Australia. 11. Mount Sinai Hospital, New York, NY. 12. Sunnybrook Health Sciences Centre, Toronto, ON, Canada. 13. UMass Memorial Medical Center, Worcester, MA.
Abstract
BACKGROUND: Several pharmacologic and nonpharmacologic therapeutic options have been used to treat cough that is not associated with a pulmonary or extrapulmonary etiology. METHODS: We conducted a systematic review to summarize the evidence supporting different cough management options in adults and children with psychogenic, tic, and habit cough. Medline, EMBASE, the Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, and Scopus were searched from the earliest inception of each database to September 2013. Content experts were contacted, and we searched bibliographies of included studies to identify additional references. RESULTS: A total of 18 uncontrolled studies were identified, enrolling 223 patients (46% male subjects, 96% children and adolescents). Psychogenic cough was the most common descriptive term used (90% of the studies). Most of the patients (95%) had no cough during sleep; barking or honking quality of cough was described in only eight studies. Hypnosis (three studies), suggestion therapy (four studies), and counseling and reassurance (seven studies) were the most commonly used interventions. Hypnosis was effective in resolving cough in 78% of the patients and improving it in another 5%. Suggestion therapy resolved cough successfully in 96% of the patients. The greatest majority of improvements noted with these forms of therapy occurred in the pediatric age group. The quality of evidence is low due to the lack of control groups, the retrospective nature of all the studies, heterogeneity of definitions and diagnostic criteria, and the high likelihood of reporting bias. CONCLUSIONS: Only low-quality evidence exists to support a particular strategy to define and treat psychogenic, habit, and tic cough. Patient values, preferences, and availability of potential therapies should guide treatment choice.
BACKGROUND: Several pharmacologic and nonpharmacologic therapeutic options have been used to treat cough that is not associated with a pulmonary or extrapulmonary etiology. METHODS: We conducted a systematic review to summarize the evidence supporting different cough management options in adults and children with psychogenic, tic, and habit cough. Medline, EMBASE, the Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, and Scopus were searched from the earliest inception of each database to September 2013. Content experts were contacted, and we searched bibliographies of included studies to identify additional references. RESULTS: A total of 18 uncontrolled studies were identified, enrolling 223 patients (46% male subjects, 96% children and adolescents). Psychogenic cough was the most common descriptive term used (90% of the studies). Most of the patients (95%) had no cough during sleep; barking or honking quality of cough was described in only eight studies. Hypnosis (three studies), suggestion therapy (four studies), and counseling and reassurance (seven studies) were the most commonly used interventions. Hypnosis was effective in resolving cough in 78% of the patients and improving it in another 5%. Suggestion therapy resolved cough successfully in 96% of the patients. The greatest majority of improvements noted with these forms of therapy occurred in the pediatric age group. The quality of evidence is low due to the lack of control groups, the retrospective nature of all the studies, heterogeneity of definitions and diagnostic criteria, and the high likelihood of reporting bias. CONCLUSIONS: Only low-quality evidence exists to support a particular strategy to define and treat psychogenic, habit, and tic cough. Patient values, preferences, and availability of potential therapies should guide treatment choice.
Authors: Alyn H Morice; Eva Millqvist; Kristina Bieksiene; Surinder S Birring; Peter Dicpinigaitis; Christian Domingo Ribas; Michele Hilton Boon; Ahmad Kantar; Kefang Lai; Lorcan McGarvey; David Rigau; Imran Satia; Jacky Smith; Woo-Jung Song; Thomy Tonia; Jan W K van den Berg; Mirjam J G van Manen; Angela Zacharasiewicz Journal: Eur Respir J Date: 2020-01-02 Impact factor: 16.671
Authors: Anne E Vertigan; Mohammad H Murad; Tamara Pringsheim; Anthony Feinstein; Anne B Chang; Peter A Newcombe; Bruce K Rubin; Lorcan P McGarvey; Kelly Weir; Kenneth W Altman; Miles Weinberger; Richard S Irwin; Todd M Adams; Kenneth W Altman; Alan F Barker; Surinder S Birring; Fiona Blackhall; Donald C Bolser; Louis-Philippe Boulet; Sidney S Braman; Christopher Brightling; Priscilla Callahan-Lyon; Brendan J Canning; Anne B Chang; Remy Coeytaux; Terrie Cowley; Paul Davenport; Rebecca L Diekemper; Satoru Ebihara; Ali A El Solh; Patricio Escalante; Anthony Feinstein; Stephen K Field; Dina Fisher; Cynthia T French; Peter Gibson; Philip Gold; Michael K Gould; Cameron Grant; Susan M Harding; Anthony Harnden; Adam T Hill; Richard S Irwin; Peter J Kahrilas; Karina A Keogh; Andrew P Lane; Kaiser Lim; Mark A Malesker; Peter Mazzone; Stuart Mazzone; Douglas C McCrory; Lorcan McGarvey; Alex Molasiotis; M Hassan Murad; Peter Newcombe; Huong Q Nguyen; John Oppenheimer; David Prezant; Tamara Pringsheim; Marcos I Restrepo; Mark Rosen; Bruce Rubin; Jay H Ryu; Jaclyn Smith; Susan M Tarlo; Anne E Vertigan; Gang Wang; Miles Weinberger; Kelly Weir; Renda Soylemez Wiener Journal: Chest Date: 2015-07 Impact factor: 9.410